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Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the…

Instrumentation and Detectors · Physics 2013-06-05 Donald F. Smith , Andras Kiss , Franklin E. Leach , Errol W. Robinson , Ljiljana Paša-Tolić , Ron M. A. Heeren

We proposed a deconvolution optical-resolution photoacoustic microscope for high -resolution imaging of brain. The focal spot of the photoacoustic microscopy is measured to obtain the lateral PSF (point spread function) of the system.…

Medical Physics · Physics 2020-11-05 Xianlin Song , Lingfang Song , Anqing Chen , Jianshuang Wei

Morphology based analysis of cell types has been an area of great interest to the neuroscience community for several decades. Recently, high resolution electron microscopy (EM) datasets of the mouse brain have opened up opportunities for…

We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…

Three-dimensional reconstruction of cortical surfaces from MRI for morphometric analysis is fundamental for understanding brain structure. While high-field MRI (HF-MRI) is standard in research and clinical settings, its limited availability…

Background: Cardiovascular magnetic resonance imaging (CMR) is a well established imaging tool for diagnosing and managing cardiac conditions. The integration of exercise stress with CMR (ExCMR) can enhance its diagnostic capacity. Despite…

Signal Processing · Electrical Eng. & Systems 2025-04-22 Preethi Chandrasekaran , Chong Chen , Yingmin Liu , Syed Murtaza Arshad , Christopher Crabtree , Matthew Tong , Yuchi Han , Rizwan Ahmad

Standard coils can cause inhomogeneities due to the standing wave patterns at ultra high field MRI. This B1 inhomogeneity can be overcome using the travelling-wave MRI (twMRI) approach. The ma- jority of twMRI research has been done with…

Medical Physics · Physics 2015-11-12 Fabian Vazquez , Oscar Marrufo , Rodrigo Martin , Sergio Solis , Alfredo O. Rodriguez

The ability to achieve submillimter isotropic resolution diffusion MR imaging (dMRI) is critically important to study fine-scale brain structures, particularly in the cortex. One of the major challenges in performing submillimeter dMRI is…

Medical Physics · Physics 2020-12-08 Wei-Tang Chang , Khoi Minh Huynh , Pew-Thian Yap , Weili Lin

The loop-gap resonator (LGR) was originally developed to provide a uniform microwave magnetic field on a sample for electron spin resonance (ESR) experiments. The LGR is composed of one or more loops and gaps acting as inductances and…

Applied Physics · Physics 2019-10-29 Matthew M. Libersky , Daniel M. Silevitch , Ammar Kouki

In this work, we present a neuromorphic system that combines for the first time a neural recording headstage with a signal-to-spike conversion circuit and a multi-core spiking neural network (SNN) architecture on the same die for recording,…

Signal Processing · Electrical Eng. & Systems 2021-06-09 Mohammadali Sharifshazileh , Karla Burelo , Johannes Sarnthein , Giacomo Indiveri

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Objective. Exploring neural activity behind synchronization and time locking in brain circuits is one of the most important tasks in neuroscience. Our goal was to design and characterize a microelectrode array (MEA) system specifically for…

Neurons and Cognition · Quantitative Biology 2017-08-03 Gergely Marton , Peter Baracskay , Barbara Cseri , Bela Plosz , Gabor Juhasz , Zoltan Fekete , Anita Pongracz

We present a resonant-mode, transverse-field, radio-frequency (rf) neutron spin flipper design that uses high-temperature superconducting films to ensure sharp transitions between uniform magnetic field regions. Resonant mode allows for low…

Purpose: To address the systematic bias in whole-brain dual flip angle (DFA) T1-mapping at 7T by optimizing the flip angle pair and carefully selecting RF pulse shape and duration. Theory and Methods: Spoiled gradient echoes can be used to…

Medical Physics · Physics 2020-01-28 H. Olsson , M. Andersen , R. Wirestam , J. Lätt , G. Helms

In vivo fluorescence imaging in the second near-infrared window (1.0-1.7 microns) can afford deep tissue penetration and high spatial resolution, owing to the reduced scattering of long-wavelength photons. Here, we synthesize a series of…

Segmenting the fine structure of the mouse brain on magnetic resonance (MR) images is critical for delineating morphological regions, analyzing brain function, and understanding their relationships. Compared to a single MRI modality,…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Ziqi Yu , Xiaoyang Han , Shengjie Zhang , Jianfeng Feng , Tingying Peng , Xiao-Yong Zhang

Magnetic resonance imaging at ultra-low fields (ULF MRI) is a promising new imaging method that uses SQUID sensors to measure the spatially encoded precession of pre-polarized nuclear spin populations at a microtesla-range measurement…

Medical Physics · Physics 2007-10-18 V. S. Zotev , A. N. Matlashov , P. L. Volegov , A. V. Urbaitis , M. A. Espy , R. H. Kraus

To date, brain imaging has largely relied on X-ray computed tomography and magnetic resonance angiography with limited spatial resolution and long scanning times. Fluorescence-based brain imaging in the visible and traditional near-infrared…

Wireless mouse rings offer subtle, reliable pointing interactions for wearable computing platforms. However, the small battery below 27 mAh in the miniature rings restricts the ring's continuous lifespan to just 1-10 hours, because current…

Human-Computer Interaction · Computer Science 2025-07-29 Yifan Li , Masaaki Fukumoto , Mohamed Kari , Shigemi Ishida , Akihito Noda , Tomoyuki Yokota , Takao Someya , Yoshihiro Kawahara , Ryo Takahashi

Neural networks have shown great potential in compressing volume data for visualization. However, due to the high cost of training and inference, such volumetric neural representations have thus far only been applied to offline data…

Graphics · Computer Science 2023-07-03 Qi Wu , David Bauer , Michael J. Doyle , Kwan-Liu Ma