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Positronium-based imaging requires realistic modelling of positronium (Ps) decay in matter. We introduce a modular Ps decay model implemented in GATE 9.4 and GATE 10, enabling the definition of an arbitrary number of decay channels…

In this work, we present modeling and imaging performance of a dual panel limited-angle TOF-PET system for intraoperative surgical applications using GATE monte carlo toolkit. Several detector parameters such as detector pixel dimensions,…

Medical Physics · Physics 2024-02-13 Salar Sajedi , Yuemeng Feng , Hamid Sabet

Position Emission Tomography (PET) is an advanced clinical diagnostic imaging technique for nuclear medicine. Small animal PET is increasingly uesd for studying the animal model of disease, new drugs and new therapies. A prototype of…

Instrumentation and Detectors · Physics 2019-09-26 Peipei Deng , Lei Zhao , Jiaming Lu , Bowen Li , Ruoshi Dong , Shubin Liu , Qi An

The low cost and high resolution gas-based Multi-gap Resistive Plate Chamber (MRPC) opens a new possibility to find an efficient alternative detector for Time of Flight (TOF) based Positron Emission Tomography, where the sensitivity of the…

Instrumentation and Detectors · Physics 2011-06-30 A. Banerjee , S. Chattopadhyay

The aim of this study was to optimize the design of a monolithic LGSO scintillation crystal and micro parallel-hole collimator for the development of a small-animal single photon emission computed tomography (SPECT) system with compact…

Medical Physics · Physics 2015-03-13 Joong Hyun Kim , Mikiko Ito , Soo Mee Kim , Seong Jong Hong , Jae Sung Lee

We present a method and preliminary results of the image reconstruction in the Jagiellonian PET tomograph. Using GATE (Geant4 Application for Tomographic Emission), interactions of the 511 keV photons with a cylindrical detector were…

We report on the measurements performed using a 22Na source on a detector element for an MRI-compatible TOF-PET endorectal prostate probe, with Depth-Of-Interaction sensitivity. It is made from a LYSO scintillator crystal, wrapped with…

Instrumentation and Detectors · Physics 2015-06-11 Luigi Cosentino , Paolo Finocchiaro , Alfio Pappalardo , Franco Garibaldi

A systematic study is conducted to understand the coincident resolving time (CRT) for a pair of Lutetium-yttrium oxyorthosilicate (LYSO) and the plastic scintillation detector bars under the Geant4 framework. Crystals are coupled to a…

Instrumentation and Detectors · Physics 2025-10-17 Davinder Siwal , P. K. Mohanty , D. Bose , A. Jain

Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

18F-fluorodeoxyglucose (18F-FDG) Positron Emission Tomography (PET) imaging usually needs a full-dose radioactive tracer to obtain satisfactory diagnostic results, which raises concerns about the potential health risks of radiation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Yu Fu , Shunjie Dong , Yi Liao , Le Xue , Yuanfan Xu , Feng Li , Qianqian Yang , Tianbai Yu , Mei Tian , Cheng Zhuo

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

Depth-of-interaction (DOI) encoding is an effective strategy for reducing parallax error and preserving spatial resolution in positron emission tomography (PET), particularly in compact small-animal scanners. To enable efficient…

Medical Physics · Physics 2026-03-10 Satzhan Sitmukhambetov , Junwei Du , Mingwu Jin , Yujie Chi

J-PET is a photon detector built of plastic scintillators, which already has been commissioned for CPT studies in the decays of positronium. In the first experiment, J-PET has achieved a sensitivity to CPT violation at a level of 10^{-4},…

High Energy Physics - Phenomenology · Physics 2023-02-28 Neha Chug , Aleksander Gajos

Cadmium zinc telluride (CdZnTe, CZT) radiation detectors are suitable for a variety of applications, due to their high spatial resolution and spectroscopic energy performance at room temperature. However, state-of-the-art detector systems…

Instrumentation and Detectors · Physics 2016-10-13 P. Födisch , M. Berthel , B. Lange , T. Kirschke , W. Enghardt , P. Kaever

We present results from a detailed GEANT4 simulation of a proposed Muon Tomography System that employs compact Micro Pattern Gas Detectors with high spatial resolution. A basic Point-Of-Closest-Approach algorithm is applied to reconstructed…

Instrumentation and Detectors · Physics 2016-11-15 Kondo Gnanvo , Patrick Ford , Jennifer Helsby , Richie Hoch , Debasis Mitra , Marcus Hohlmann

The aim of this study is to design and evaluate a simple free running Analog-Digital Converter (ADC) based on the Field Programmable Gate Array (FPGA) device to accomplish the energy and position readout of the silicon photomultiplier…

Instrumentation and Detectors · Physics 2021-08-19 Cong Ma , Xue Dong , Li Yu , Wubin Wang , Xiaokun Zhao , Xing Li , Zhenqing Huang , Guocheng Wu , Lei Lu , Hansheng Chen

We study the potential of the MCP-PMT read-out to detect single photo-electron using transmission lines. Such a solution limits the number of read-out channels, has a uniform time resolution across the PMT surface and provides…

Instrumentation and Detectors · Physics 2022-01-26 M. Follin , R. Chyzh , C. -H. Sung , D. Breton , J. Maalmi , T. Chaminade , E. Delagnes , K. Schäfers , C. Weinheimer , D. Yvon , V. Sharyy

Positron emission tomography (PET) is widely used to assess metabolic activity, but its application is limited by the availability of radiotracers. 18F-labeled fluorodeoxyglucose (18F-FDG) is the most commonly used tracer but shows limited…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Fang Chen , Weifeng Zhang , Xingyu Ai , BingXuan Li , An Li , Qiegen Liu

The TT-PET collaboration is developing an MRI-compatible small animal PET scanner in which the sensitive element is a monolithic silicon pixel ASIC targeting 30 ps RMS time resolution. The photon-detection technique is based on a stack of…

PETALO (Positron Emission TOF Apparatus based on Liquid xenOn) exploits the unique characteristics of liquid xenon as a scintillator for use in a PET detector. Here initial simulation studies are detailed which highlight the potential of…