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The spreading of bacterial colonies at solid-air interfaces is determined by the physico-chemical properties of the involved interfaces. The production of surfactant molecules by bacteria is a widespread strategy that allows the colony to…

Biological Physics · Physics 2018-07-24 Sarah Trinschek , Karin John , Uwe Thiele

Navigation of microorganisms is controlled by internal processes ultimately sensitive to mechanical or chemical signaling encountered along the path. In many natural environments, such as porous soils or physiological ducts, motile species…

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains…

In natural environments, solid surfaces present both opportunities and challenges for bacteria. On one hand, they serve as platforms for biofilm formation, crucial for bacterial colonization and resilience in harsh conditions. On the other…

Biological Physics · Physics 2025-07-01 Antai Tao , Guangzhe Liu , Rongjing Zhang , Junhua Yuan

Cells coexist together in colonies or as tissues. Their behaviour is controlled by an interplay between intercellular forces and biochemical regulation. We develop a simple model of the cell cycle, the fundamental regulatory network…

Biological Physics · Physics 2021-08-04 Jintao Li , Simon K. Schnyder , Matthew S. Turner , Ryoichi Yamamoto

Tuning cell rearrangements is essential in collective cell movement that underlies cancer progression, wound repair, and embryonic development. A key question is how tissue material properties and morphology emerge from cellular factors…

Biological Physics · Physics 2025-07-15 Soumyadipta Ray , Santidan Biswas , Dipjyoti Das

The duality between deformations of elastic bodies and non-inertial flows in viscous liquids has been a guiding principle in decades of research. However, this duality is broken when a spheroidal or other doubly-curved liquid film is…

Soft Condensed Matter · Physics 2023-07-20 Benny Davidovitch , Avraham Klein

Understanding how growth induces form is a longstanding biological question. Many studies concentrated on the shapes of plant cells, fungi or bacteria. Some others have shown the importance of the mechanical properties of bacterial walls…

Biological Physics · Physics 2007-05-23 Arezki Boudaoud

Through mechanical forces, biological cells remodel the surrounding collagen network, generating striking deformation patterns. Tethers-tracts of high densification and fiber alignment-form between cells, thinner bands emanate from cell…

The recent discovery of a lateral organization in cell membranes due to small structures called 'rafts' has motivated a lot of biological and physico-chemical studies. A new experiment on a model system has shown a spectacular budding…

Subcellular Processes · Quantitative Biology 2009-11-10 Jean-Marc Allain , Martine Ben Amar

Bacteria on surfaces exhibit collective behaviors, such as active turbulence and active stresses, which result from their motility, growth, and interactions with their local surroundings. However, interfacial deformations on soft surfaces…

Soft Condensed Matter · Physics 2022-09-13 Vincent Hickl , Gabriel Juarez

Biofilms are spatially organized microorganism colonies embedded in a self-produced matrix, conferring to the microbial community resistance to environmental stresses. Motile bacteria have been observed swimming in the matrix of pathogenic…

Quantitative Methods · Quantitative Biology 2022-05-24 Guillaume Ravel , Michel Bergmann , Alain Trubuil , Julien Deschamps , Romain Briandet , Simon Labarthe

Formation and rupture of vesicles is a fundamental process underlying diverse phenomena in biology, materials science, and biomedical applications. Vesicles form when the area of a growing disk-like membrane exceeds a critical value at…

Soft Condensed Matter · Physics 2025-11-11 Seungwoo Shin , Federico Cao , Robert A. Pelcovits , Thomas R. Powers , Zvonimir Dogic

We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability. Several shapes are…

Biological Physics · Physics 2012-07-09 Edouard Hannezo , Jean-Francois Joanny , Jacques Prost

In vivo, eukaryotic cells are embedded in a matrix environment, where they grow and develop. Generally, this extracellular matrix (ECM) is an anisotropic fibrous structure, through which macromolecules and biochemical signaling molecules at…

Biological Physics · Physics 2020-01-06 David Gomez , Sari Natan , Yair Shokef , Ayelet Lesman

Controlling and suppressing bacterial accumulation at solid surfaces is essential for preventing biofilm formation and biofouling. Whereas various chemical surface treatments are known to reduce cell accumulation and attachment, the role of…

Biological Physics · Physics 2019-05-29 Rachel Mok , Jörn Dunkel , Vasily Kantsler

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

Statistical Mechanics · Physics 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

We propose a model of antibiotic diffusion through a bacterial biofilm when diffusion and/or absorption barriers develop in the biofilm. The idea of this model is: We deduce details of the diffusion process in a medium in which direct…

Biological Physics · Physics 2020-09-23 Tadeusz Kosztołowicz , Ralf Metzler

Bacterial cellulose is an important class of biomaterials which can be grown in well-controlled laboratory and industrial conditions. The cellulose structure is affected by several biological, chemical and environmental factors, including…

Biological Physics · Physics 2021-07-28 Sung-Ha Hong , Jia Yang , Mahdi Davoodianidalik , Horst Punzmann , Michael Shats , Hua Xia

Cell migration is important in many biological processes, including embryonic development, cancer metastasis, and wound healing. In these tissues, a cell's motion is often strongly constrained by its neighbors, leading to glassy dynamics.…

Biological Physics · Physics 2016-01-20 Dapeng Bi , J. H. Lopez , J. M. Schwarz , M. Lisa Manning
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