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Related papers: Verticalization of bacterial biofilms

200 papers

Bacterial processes ranging from gene expression to motility and biofilm formation are constantly challenged by internal and external noise. While the importance of stochastic fluctuations has been appreciated for chemotaxis, it is…

Biological Physics · Physics 2011-07-13 Knut Drescher , Jörn Dunkel , Luis H. Cisneros , Sujoy Ganguly , Raymond E. Goldstein

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

Biological Physics · Physics 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

The evolutionary success of bacteria lies in their ability to form complex surface-associated communities in diverse biophysical settings. However, it remains poorly understood how compliance of soft surfaces, measured in terms of their…

Soft Condensed Matter · Physics 2025-08-05 Garima Rani , Anupam Sengupta

A hydrodynamic model is proposed to describe one of the most critical problems in intensive medical care units: the formation of biofilms inside central venous catheters. The incorporation of approximate solutions for the flow-limited…

We study colonies of non-motile, rod-shaped bacteria growing on solid substrates. In our model, bacteria interact purely mechanically, by pushing each other away as they grow, and consume a diffusing nutrient. We show that mechanical…

Biological Physics · Physics 2015-06-15 F. D. C. Farrell , O. Hallatschek , D. Marenduzzo , B. Waclaw

Near-field hydrodynamic interactions between bacteria and no-slip solid surfaces are the main mechanism underlying surface entrapment of bacteria. In this study, we employ a chiral two-body model to simulate bacterial dynamics near the…

Soft Condensed Matter · Physics 2026-02-25 Baopi Liu , Lu Chen , Haiqin Wang

Colonies of rod-shaped bacteria constitute a system of colloidal active matter with nematic properties. As a single initial bacterium multiplies through repeated divisions, the resulting colony quickly loses long-range orientational order,…

Biofilms, bacteria cells surrounded by a self-produced polymeric matrix, are common on medical devices and lead to many hospital infections. The biofilm lifecycle includes disassembly and dispersion, where bacteria clusters detach from the…

Quantitative Methods · Quantitative Biology 2026-05-18 Yuehui Xu , Jasmine A. F. Kreig , Zhuoran Wang , Elizabeth J. Stewart , Rayanne A. Luke , Sarah D. Olson

Bacteria invade surfaces by forming dense colonies encased in a polymer matrix. Successful settlement of founder bacteria, early microcolony development and later macroscopic spreading of these biofilms on surfaces rely on complex physical…

Soft Condensed Matter · Physics 2025-08-27 Anthony Pietz , Karin John , Uwe Thiele

Biofilms are microbial collectives that occupy a diverse array of surfaces. The function and evolution of biofilms are strongly influenced by the spatial arrangement of different strains and species within them, but how spatiotemporal…

Populations and Evolution · Quantitative Biology 2018-07-04 Ricardo Martinez-Garcia , Carey D. Nadell , Raimo Hartmann , Knut Drescher , Juan A. Bonachela

Flagellated bacteria are hydrodynamically attracted to rigid walls, yet past work shows a 'hovering' state where they swim stably at a finite height above surfaces. We use numerics and theory to reveal the physical origin of hovering.…

Biological Physics · Physics 2024-09-17 Pyae Hein Htet , Debasish Das , Eric Lauga

Bacterial attachment to a fluid interface can lead to the formation of a film with physicochemical properties that evolve with time. We study the time evolution of interface (micro)mechanics for interfaces between oil and bacterial…

Soft Condensed Matter · Physics 2015-03-26 Liana Vaccari , Daniel Allan , Nima Sharifi-Mood , Aayush Singh , Robert Leheny , Kathleen Stebe

Microscopic organisms, such as bacteria, have the ability of colonizing surfaces and developing biofilms that can determine diseases and infections. Most bacteria secrete a significant amount of extracellular polymer substances that are…

Biological Physics · Physics 2021-05-19 Francisco Javier Lobo-Cabrera , Alessandro Patti , Fernando Govantes , Alejandro Cuetos

Bacterial colonies are a well-known example of living active matter, exhibiting collective behaviors such as nematic alignment and collective motion that play an important role in the spread of microbial infections. While the underlying…

We study a generic model for the polarisation and motility of self-propelled soft objects, biological cells or biomimetic systems, interacting with a viscous substrate. The active forces generated by the cell on the substrate are modelled…

Soft Condensed Matter · Physics 2015-06-23 M. Leoni , P. Sens

This study explores the application of elongated particle interaction models, traditionally used in liquid crystal phase research, in the context of early bacterial biofilm development. Through computer simulations using an agent-based…

Soft Condensed Matter · Physics 2025-11-05 Gabriel Santos-Díaz , Álvaro Rodríguez-Rivas , Alejandro Cuetos

Mechanical interactions among cells in a growing microbial colony can significantly influence the colony's spatial genetic structure and, thus, evolutionary outcomes such as the fates of rare mutations. Here, we computationally investigate…

Soft Condensed Matter · Physics 2025-01-22 Mateusz Ratman , Jimmy Gonzalez Nuñez , Daniel A. Beller

The sessile microbial communities known as biofilms exhibit varying architectures as environmental factors are varied, which for immersed biofilms includes the shear rate of the surrounding flow. Here we modify an established agent-based…

Biological Physics · Physics 2014-03-11 D. A. Head

Bacterial communities such as biofilms are widely recognised as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can…

Quantitative Methods · Quantitative Biology 2007-05-23 Leah R. Johnson

To provide insight into the basic properties of emerging structures when bacteria or other microorganisms conquer surfaces, it is crucial to analyze their growth behavior during the formation of thin films. In this regard, many theoretical…

Soft Condensed Matter · Physics 2025-05-23 Yuta Kuroda , Takeshi Kawasaki , Andreas M. Menzel