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Text mining the relations between chemicals and proteins is an increasingly important task. The CHEMPROT track at BioCreative VI aims to promote the development and evaluation of systems that can automatically detect the chemical-protein…

Computation and Language · Computer Science 2018-02-06 Yifan Peng , Anthony Rios , Ramakanth Kavuluru , Zhiyong Lu

Information retrieval (IR) is essential in biomedical knowledge acquisition and clinical decision support. While recent progress has shown that language model encoders perform better semantic retrieval, training such models requires…

Information Retrieval · Computer Science 2024-01-17 Qiao Jin , Won Kim , Qingyu Chen , Donald C. Comeau , Lana Yeganova , W. John Wilbur , Zhiyong Lu

Current methods for investigation of receptor - ligand interactions in drug discovery are based on three-dimensional complementarity of receptor and ligand surfaces, and they include pharmacophore modelling, QSAR, molecular docking etc.…

Biomolecules · Quantitative Biology 2020-04-16 Milan Sencanski , Neven Sumonja , Vladimir Perovic , Sanja Glisic , Nevena Veljkovic , Veljko Veljkovic

We present RepRank, an unsupervised graph-based ranking model for extractive multi-document summarization in which the similarity between words, sentences, and word-to-sentence can be estimated by the distances between their vector…

Computation and Language · Computer Science 2023-07-25 Zongyi Li , Xiaoqing Zheng , Jun He

Generating useful network summaries is a challenging and important problem with several applications like sensemaking, visualization, and compression. However, most of the current work in this space do not take human feedback into account…

Information retrieval (IR) for precision medicine (PM) often involves looking for multiple pieces of evidence that characterize a patient case. This typically includes at least the name of a condition and a genetic variation that applies to…

Computation and Language · Computer Science 2020-12-18 Jiho Noh , Ramakanth Kavuluru

Gene/protein interactions provide critical information for a thorough understanding of cellular processes. Recently, considerable interest and effort has been focused on the construction and analysis of genome-wide gene networks. The large…

Molecular Networks · Quantitative Biology 2022-04-25 Xin Li , Hsinchun Chen , Zan Huang , Hua Su , Jesse D. Martinez

Telecom services are at the core of today's societies' everyday needs. The availability of numerous online forums and discussion platforms enables telecom providers to improve their services by exploring the views of their customers to…

Computation and Language · Computer Science 2025-04-21 Hesham Abdelmotaleb , Craig McNeile , Malgorzata Wojtys

The Internet has become a very powerful platform where diverse medical information are expressed daily. Recently, a huge growth is seen in searches like symptoms, diseases, medicines, and many other health related queries around the globe.…

Multiagent Systems · Computer Science 2021-01-26 Nilanjan Sinhababu , Rahul Saxena , Monalisa Sarma , Debasis Samanta

Deep learning-based computational methods have achieved promising results in predicting protein-protein interactions (PPIs). However, existing benchmarks predominantly focus on isolated pairwise evaluations, overlooking a model's capability…

Machine Learning · Computer Science 2025-10-23 Xinzhe Zheng , Hao Du , Fanding Xu , Jinzhe Li , Zhiyuan Liu , Wenkang Wang , Tao Chen , Wanli Ouyang , Stan Z. Li , Yan Lu , Nanqing Dong , Yang Zhang

Traditional biomedical version of embeddings obtained from pre-trained language models have recently shown state-of-the-art results for relation extraction (RE) tasks in the medical domain. In this paper, we explore how to incorporate…

Computation and Language · Computer Science 2020-12-23 Ishani Mondal

The best evidence concerning comparative treatment effectiveness comes from clinical trials, the results of which are reported in unstructured articles. Medical experts must manually extract information from articles to inform…

Computation and Language · Computer Science 2022-01-11 Benjamin E. Nye , Jay DeYoung , Eric Lehman , Ani Nenkova , Iain J. Marshall , Byron C. Wallace

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

Computation and Language · Computer Science 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

Nature has inspired various ground-breaking technological developments in applications ranging from robotics to aerospace engineering and the manufacturing of medical devices. However, accessing the information captured in scientific…

Computation and Language · Computer Science 2020-05-27 Ruben Kruiper , Julian F. V. Vincent , Jessica Chen-Burger , Marc P. Y. Desmulliez , Ioannis Konstas

A major difficulty in applying word vector embeddings in IR is in devising an effective and efficient strategy for obtaining representations of compound units of text, such as whole documents, (in comparison to the atomic words), for the…

Information Retrieval · Computer Science 2016-06-28 Dwaipayan Roy , Debasis Ganguly , Mandar Mitra , Gareth J. F. Jones

Objective: Medical relations are the core components of medical knowledge graphs that are needed for healthcare artificial intelligence. However, the requirement of expert annotation by conventional algorithm development processes creates a…

Machine Learning · Computer Science 2020-09-09 Yucong Lin , Keming Lu , Yulin Chen , Chuan Hong , Sheng Yu

In dialog system, dialog act recognition and sentiment classification are two correlative tasks to capture speakers intentions, where dialog act and sentiment can indicate the explicit and the implicit intentions separately. Most of the…

Computation and Language · Computer Science 2020-08-18 Libo Qin , Wanxiang Che , Yangming Li , Minheng Ni , Ting Liu

Protein analysis tasks arising in healthcare settings often require accurate reasoning under protein sequence constraints, involving tasks such as functional interpretation of disease-related variants, protein-level analysis for clinical…

Artificial Intelligence · Computer Science 2026-03-03 Congying Liu , Taihao Li , Ming Huang , Xingyuan Wei , Peipei Liu , Yiqing Shen , Yanxu Mao , Tiehan Cui

Knowledge of a disease includes information of various aspects of the disease, such as signs and symptoms, diagnosis and treatment. This disease knowledge is critical for many health-related and biomedical tasks, including consumer health…

Computation and Language · Computer Science 2020-10-09 Yun He , Ziwei Zhu , Yin Zhang , Qin Chen , James Caverlee

Manually labelling large collections of text data is a time-consuming, expensive, and laborious task, but one that is necessary to support machine learning based on text datasets. Active learning has been shown to be an effective way to…

Computation and Language · Computer Science 2019-10-11 Jinghui Lu , Maeve Henchion , Brian Mac Namee