English
Related papers

Related papers: INtERAcT: Interaction Network Inference from Vecto…

200 papers

We participated, in the Article Classification and the Interaction Method subtasks (ACT and IMT, respectively) of the Protein-Protein Interaction task of the BioCreative III Challenge. For the ACT, we pursued an extensive testing of…

Quantitative Methods · Quantitative Biology 2011-04-25 Anália Lourenço , Michael Conover , Andrew Wong , Azadeh Nematzadeh , Fengxia Pan , Hagit Shatkay , Luis M. Rocha

Motivation: Protein-protein interactions (PPI) are critical to the function of proteins in both normal and diseased cells, and many critical protein functions are mediated by interactions.Knowledge of the nature of these interactions is…

Computation and Language · Computer Science 2022-01-10 Aparna Elangovan , Melissa Davis , Karin Verspoor

Detecting protein-protein interactions (PPIs) is crucial for understanding genetic mechanisms, disease pathogenesis, and drug design. However, with the fast-paced growth of biomedical literature, there is a growing need for automated and…

Computation and Language · Computer Science 2023-12-14 Hasin Rehana , Nur Bengisu Çam , Mert Basmaci , Jie Zheng , Christianah Jemiyo , Yongqun He , Arzucan Özgür , Junguk Hur

Document-Level Biomedical Relation Extraction (Bio-RE) aims to identify relations between biomedical entities within extensive texts, serving as a crucial subfield of biomedical text mining. Existing Bio-RE methods struggle with…

Computation and Language · Computer Science 2025-01-10 Yufei Shang , Yanrong Guo , Shijie Hao , Richang Hong

Word embeddings have found their way into a wide range of natural language processing tasks including those in the biomedical domain. While these vector representations successfully capture semantic and syntactic word relations, hidden…

Detecting keywords in texts is important for many text mining applications. Graph-based methods have been commonly used to automatically find the key concepts in texts, however, relevant information provided by embeddings has not been…

Computation and Language · Computer Science 2022-05-05 Jorge A. V. Tohalino , Thiago C. Silva , Diego R. Amancio

Motivation: The biomedical literature contains a wealth of chemical-protein interactions (CPIs). Automatically extracting CPIs described in biomedical literature is essential for drug discovery, precision medicine, as well as basic…

Computation and Language · Computer Science 2020-04-27 Cong Sun , Zhihao Yang , Leilei Su , Lei Wang , Yin Zhang , Hongfei Lin , Jian Wang

Neural embeddings are a popular set of methods for representing words, phrases or text as a low dimensional vector (typically 50-500 dimensions). However, it is difficult to interpret these dimensions in a meaningful manner, and creating…

Computation and Language · Computer Science 2018-01-10 Neil R. Smalheiser , Gary Bonifield

In recent years extracting relevant information from biomedical and clinical texts such as research articles, discharge summaries, or electronic health records have been a subject of many research efforts and shared challenges. Relation…

Computation and Language · Computer Science 2016-07-01 Sunil Kumar Sahu , Ashish Anand , Krishnadev Oruganty , Mahanandeeshwar Gattu

Understanding how molecular alterations propagate across biological systems to drive disease remains a central challenge. Although high-throughput profiling enables comprehensive characterization of tumor states, most models neglect…

Quantitative Methods · Quantitative Biology 2026-05-11 Kyle Higgins , Guadalupe Gonzalez , Dennis Veselkov , Ivan Laponogov , Kirill Veselkov

Compared to the general news domain, information extraction (IE) from biomedical text requires much broader domain knowledge. However, many previous IE methods do not utilize any external knowledge during inference. Due to the exponential…

Computation and Language · Computer Science 2021-06-02 Tuan Lai , Heng Ji , ChengXiang Zhai , Quan Hung Tran

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

Protein-protein interaction extraction is the key precondition of the construction of protein knowledge network, and it is very important for the research in the biomedicine. This paper extracted directional protein-protein interaction from…

Computation and Language · Computer Science 2014-08-25 Peilei Liu , Ting Wang

In recent years, protein-text models have gained significant attention for their potential in protein generation and understanding. Current approaches focus on integrating protein-related knowledge into large language models through…

Computation and Language · Computer Science 2025-11-11 Juntong Wu , Zijing Liu , He Cao , Hao Li , Bin Feng , Zishan Shu , Ke Yu , Li Yuan , Yu Li

In this research, we present our work participation for the DrugProt task of BioCreative VII challenge. Drug-target interactions (DTIs) are critical for drug discovery and repurposing, which are often manually extracted from the…

Computation and Language · Computer Science 2021-11-09 Jehad Aldahdooh , Ziaurrehman Tanoli , Jing Tang

We address the challenge of building domain-specific knowledge models for industrial use cases, where labelled data and taxonomic information is initially scarce. Our focus is on inductive link prediction models as a basis for practical…

Machine Learning · Computer Science 2023-01-03 Felix Hamann , Adrian Ulges , Maurice Falk

Text mining and information extraction for the medical domain has focused on scientific text generated by researchers. However, their direct access to individual patient experiences or patient-doctor interactions can be limited. Information…

Computation and Language · Computer Science 2022-04-22 Amelie Wührl , Roman Klinger

Capturing the semantics of related biological concepts, such as genes and mutations, is of significant importance to many research tasks in computational biology such as protein-protein interaction detection, gene-drug association…

Computation and Language · Computer Science 2020-07-01 Qingyu Chen , Kyubum Lee , Shankai Yan , Sun Kim , Chih-Hsuan Wei , Zhiyong Lu

Identifying the relations between chemicals and proteins is an important text mining task. BioCreative VII track 1 DrugProt task aims to promote the development and evaluation of systems that can automatically detect relations between…

Computation and Language · Computer Science 2021-12-07 Mehmet Efruz Karabulut , K. Vijay-Shanker , Yifan Peng

The way we analyse clinical texts has undergone major changes over the last years. The introduction of language models such as BERT led to adaptations for the (bio)medical domain like PubMedBERT and ClinicalBERT. These models rely on large…

Computation and Language · Computer Science 2023-09-15 Tom van Sonsbeek , Xiantong Zhen , Marcel Worring