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As molecular scientists have made progress in their ability to engineer nano-scale molecular structure, we are facing new challenges in our ability to engineer molecular dynamics (MD) and flexibility. Dynamics at the molecular scale differs…

Molecular dynamics (MD) simulations are a crucial computational tool for researchers to understand and engineer molecular structure and function in areas such as drug discovery, protein engineering, and material design. Despite their…

The potential of virtual reality (VR) to contribute to drug design and development has been recognised for many years. Hardware and software developments now mean that this potential is beginning to be realised, and VR methods are being…

Biomolecules · Quantitative Biology 2022-02-09 Rebecca K. Walters , Ella M. Gale , Jonathan Barnoud , David R. Glowacki , Adrian J. Mulholland

Simulating drug binding and unbinding is a challenge, as the rugged energy landscapes that separate bound and unbound states require extensive sampling that consumes significant computational resources. Here, we describe the use of…

This paper presents a molecular mechanics study using a molecular dynamics software (NAMD) coupled to virtual reality (VR) techniques for intuitive Bio-NanoRobotic prototyping. Using simulated Bio-Nano environments in VR, the operator can…

Biological Physics · Physics 2007-08-15 Mustapha Hamdi , Gaurav Sharma , A. Ferreira , Constantinos Mavroidis

An adventure at engineering design and modeling is possible with a Virtual Reality Environment (VRE) that uses multiple computer-generated media to let a user experience situations that are temporally and spatially prohibiting. In this…

Computational Engineering, Finance, and Science · Computer Science 2007-08-15 L. -V. Bochkareva , M. -V. Kireitseu , G. R. Tomlinson , H. Altenbach , V. Kompis , D. Hui

As computer simulations progress to increasingly complex, non-linear, and three-dimensional systems and phenomena, intuitive and immediate visualization of their results is becoming crucial. While Virtual Reality (VR) and Natural User…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-09-09 Aryaman Gupta , Ulrik Günther , Pietro Incardona , Ata Deniz Aydin , Raimund Dachselt , Stefan Gumhold , Ivo F. Sbalzarini

In this paper, we present the design of a multimodal interaction framework for intelligent virtual agents in wearable mixed reality environments, especially for interactive applications at museums, botanical gardens, and similar places.…

Human-Computer Interaction · Computer Science 2025-03-26 Ghazanfar Ali , Hong-Quan Le , Junho Kim , Seoung-won Hwang , Jae-In Hwang

Physics students now have access to interactive molecular dynamics simulations that can model and animate the motions of hundreds of particles, such as noble gas atoms, that attract each other weakly at short distances but repel strongly…

Physics Education · Physics 2015-02-27 Daniel V. Schroeder

3D modeling is becoming a well-developed field of medicine, but its applicability can be limited due to the lack of software allowing for easy utilizations of generated 3D visualizations. By leveraging recent advances in virtual reality, we…

Human-Computer Interaction · Computer Science 2020-12-07 Alex J. Deakyne , Erik N. Gaasedelen , Tinen L. Iles , Paul A. Iaizzo

The ability to precisely visualize the atomic geometry of the interactions between a drug and its protein target in structural models is critical in predicting the correct modifications in previously identified inhibitors to create more…

Biomolecules · Quantitative Biology 2018-08-14 Erick Martins Ratamero , Dom Bellini , Christopher G. Dowson , Rudolf A. Roemer

Molecular visualization software has long supported research and education in chemical and structural sciences, but consumer devices constrained to 2D inputs and outputs pose two major challenges: they poorly convey 3D nature, and 3D…

Chemical Physics · Physics 2025-09-05 Luciano A. Abriata

To fill the lack of research efforts in virtual assembly of modules and training, this paper presents a virtual manipulation of building objects in an Immersive Virtual Environment (IVE). A worker wearing a Virtual Reality (VR) head-mounted…

Computers and Society · Computer Science 2019-02-15 Mojtaba Noghabaei , Khashayar Asadi , Kevin Han

Molecular dynamics (MD) simulations provide crucial insight into molecular interactions and biomolecular function. With interactive MD simulations in VR (iMD-VR), chemists can now interact with these molecular simulations in real-time. Our…

Human-Computer Interaction · Computer Science 2024-09-13 Rhoslyn Roebuck Williams , Jonathan Barnoud , Luis Toledo , Till Holzapfel , David R. Glowacki

During VR demos we have performed over last few years, many participants (in the absence of any haptic feedback) have commented on their perceived ability to 'feel' differences between simulated molecular objects. The mechanisms for such…

Human-Computer Interaction · Computer Science 2020-05-08 Rhoslyn Roebuck Williams , Xan Varcoe , Becca R. Glowacki , Ella M. Gale , Alexander Jamieson-Binnie , David R. Glowacki

The application and implementation of collaborative embodiment in virtual reality (VR) are a critical aspect of the computer science landscape, aiming to enhance multi-user interaction and teamwork in immersive environments. A notable and…

Human-Computer Interaction · Computer Science 2025-07-28 Hongyu Zhou , Yihao Dong , Masahiko Inami , Zhanna Sarsenbayeva , Anusha Withana

Drawing tools for Virtual Reality (VR) enable users to model 3D designs from within the virtual environment itself. These tools employ sketching and sculpting techniques known from desktop-based interfaces and apply them to hand-based…

Human-Computer Interaction · Computer Science 2019-11-06 Daniele Giunchi , Stuart james , Donald Degraen , Anthony Steed

This paper presents a molecular mechanics study for new nanorobotic structures using molecular dynamics (MD) simulations coupled to virtual reality (VR) techniques. The operator can design and characterize through molecular dynamics…

Materials Science · Physics 2007-08-13 M. Hamdi , A. Ferreira

A large number of powerful, high-quality, and open-source simulation packages exist to efficiently perform molecular dynamics simulations, and their prevalence has greatly accelerated discoveries across a wide range of scientific domains.…

Soft Condensed Matter · Physics 2024-05-01 Toler H. Webb , Daniel M. Sussman

Recent advancements in virtual reality (VR) technology have enabled the creation of immersive learning environments that provide engineering students with hands-on, interactive experiences. This paper presents a novel framework for virtual…

Human-Computer Interaction · Computer Science 2026-03-30 Rafael Padilla , Özgür Keleş
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