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We introduce TempoCave, a novel visualization application for analyzing dynamic brain networks, or connectomes. TempoCave provides a range of functionality to explore metrics related to the activity patterns and modular affiliations of…

Human-Computer Interaction · Computer Science 2020-01-16 Ran Xu , Manu Mathew Thomas , Alex Leow , Olusola Ajilore , Angus G. Forbes

Objective: Endophenotypes such as brain age and fluid intelligence are important biomarkers of disease status. However, brain imaging studies to identify these biomarkers often encounter limited numbers of subjects and high dimensional…

Quantitative Methods · Quantitative Biology 2022-12-29 Anton Orlichenko , Gang Qu , Gemeng Zhang , Binish Patel , Tony W. Wilson , Julia M. Stephen , Vince D. Calhoun , Yu-Ping Wang

Understanding brain connectivity in a network-theoretic context has shown much promise in recent years. This type of analysis identifies brain organisational principles, bringing a new perspective to neuroscience. At the same time, large…

Neural and Evolutionary Computing · Computer Science 2016-11-28 Sarah Parisot , Jonathan Passerat-Palmbach , Markus D. Schirmer , Boris Gutman

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

The contribution of structural connectivity to functional brain states remains poorly understood. We present a mathematical and computational study suited to assess the structure--function issue, treating a system of Jansen--Rit neural-mass…

Neurons and Cognition · Quantitative Biology 2020-07-10 Michael Forrester , Stephen Coombes , Jonathan J. Crofts , Stamatios N. Sotiropoulos , Reuben D. O'Dea

Contemporary accounts of ongoing thought recognise it as a heterogeneous and multidimensional construct, varying in both form and content. An emerging body of evidence demonstrates that distinct types of experience are associated with…

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

Pain is an inherent part of human existence, manifesting as both physical and emotional experiences, and can be categorized as either acute or chronic. Over the years, extensive research has been conducted to understand the causes of pain…

Computation and Language · Computer Science 2025-07-14 Ancita Maria Andrade , Tanvi Banerjee , Ramakrishna Mundugar

The physical basis of consciousness is one of the most intriguing open questions that contemporary science aims to solve. By approaching the brain as an interactive information system, complex network theory has greatly contributed to…

The process of integration of inputs from several sensory modalities in the human brain is referred to as multisensory integration. Age-related cognitive decline leads to a loss in the ability of the brain to conceive multisensory inputs.…

Signal Processing · Electrical Eng. & Systems 2023-05-02 Prerna Singh , Ayush Tripathi , Lalan Kumar , Tapan Kumar Gandhi

The functional network of the brain continually adapts to changing environmental demands. The environmental changes closely connect with changes of active cognitive processes. In recent years, the network approach has emerged as a promising…

Neurons and Cognition · Quantitative Biology 2024-03-13 Ilya Ernston , Arsenii Onuchin , Timofey Adamovich

Deep, classical graph-theoretical parameters, like the size of the minimum vertex cover, the chromatic number, or the eigengap of the adjacency matrix of the graph were studied widely by mathematicians in the last century. Most researchers…

Neurons and Cognition · Quantitative Biology 2017-09-18 Balazs Szalkai , Balint Varga , Vince Grolmusz

This study leverages large-scale travel surveys for over 200,000 residents across Boston, Chicago, Hong Kong, London, and Sao Paulo. With rich individual-level data, we make systematic comparisons and reveal patterns in social mixing, which…

Artificial Intelligence · Computer Science 2026-04-15 Z. Fan , B. P. Y. Loo , F. Duarte , C. Ratti , E. Moro

The study of healthy brain development helps to better understand the brain transformation and brain connectivity patterns which happen during childhood to adulthood. This study presents a sparse machine learning solution across whole-brain…

Machine Learning · Computer Science 2019-04-03 Peyman Hosseinzadeh Kassani , Alexej Gossmann , Yu-Ping Wang

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Recently, individual-based models originally used for biological purposes revealed interesting insights into processes of the competition of languages. Within this new field of population dynamics a model considering sexual populations with…

Physics and Society · Physics 2015-06-26 Veit Schwämmle

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

Network neuroscience shed some light on the functional and structural modifications occurring to the brain associated with the phenomenology of schizophrenia. In particular, resting-state functional networks have helped our understanding of…

Neurons and Cognition · Quantitative Biology 2021-04-30 Rossana Mastrandrea , Fabrizio Piras , Andrea Gabrielli , Nerisa Banaj , Guido Caldarelli , Gianfranco Spalletta , Tommaso Gili

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Adaptive behavior, cognition and emotion are the result of a bewildering variety of brain spatiotemporal activity patterns. An important problem in neuroscience is to understand the mechanism by which the human brain's 100 billion neurons…

Neurons and Cognition · Quantitative Biology 2011-05-09 Paul Expert , Renaud Lambiotte , Dante R. Chialvo , Kim Christensen , Henrik Jeldtoft Jensen , David J. Sharp , Federico Turkheimer