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Brain Age (BA) estimation via Deep Learning has become a strong and reliable bio-marker for brain health, but the black-box nature of Neural Networks does not easily allow insight into the features of brain ageing.We trained a ResNet model…

Neurons and Cognition · Quantitative Biology 2022-07-26 Daniel Taylor , Jonathan Shock , Deshendran Moodley , Jonathan Ipser , Matthias Treder

Creativity is a core cognitive capacity underlying innovation and adaptive problem solving, yet how it is represented in the brain's intrinsic functional architecture is not fully understood. While resting-state fMRI studies have identified…

Neurons and Cognition · Quantitative Biology 2026-01-21 Samir Damji , Simrut Kurry , Shazia'Ayn Babul , Joydeep Bhattacharya , Naznin Virji-Babul

In order to understand the complex cognitive functions of the human brain, it is essential to study the structural connectome, i.e., the wiring of different brain regions to each other through axonal pathways. However, the high degree of…

Neurons and Cognition · Quantitative Biology 2021-01-25 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

The functional brain network emerges from the complex, coordinated activity of distinct yet connected regions, which underlie the diverse repertoire of human cognitive functions. Structural Balance Theory (SBT) has been successfully applied…

Neurons and Cognition · Quantitative Biology 2025-09-09 Fahimeh Ahmadi , Zahra Moradimanesh , Reza Khosrowabadi , G. Reza Jafari

Activity in the human brain moves between diverse functional states to meet the demands of our dynamic environment, but fundamental principles guiding these transitions remain poorly understood. Here, we capitalize on recent advances in…

There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with…

Machine Learning · Statistics 2021-09-14 Meimei Liu , Zhengwu Zhang , David B. Dunson

In our previous study we have shown that the female connectomes have significantly better, deep graph-theoretical parameters, related to superior "connectivity", than the connectome of the males. Since the average female brain is smaller…

Neurons and Cognition · Quantitative Biology 2015-12-04 Balázs Szalkai , Bálint Varga , Vince Grolmusz

We introduce an innovative, data-driven topological data analysis (TDA) technique for estimating the state spaces of dynamically changing functional human brain networks at rest. Our method utilizes the Wasserstein distance to measure…

Algebraic Topology · Mathematics 2024-04-18 Moo K. Chung , Shih-Gu Huang , Ian C. Carroll , Vince D. Calhoun , H. Hill Goldsmith

We study possible relations between the structure of the connectome, white matter connecting different regions of brain, and Alzheimer disease. Regression models in covariates including age, gender and disease status for the extent of white…

Methodology · Statistics 2021-04-22 Arkaprava Roy , Subhashis Ghosal , Jeffrey Prescott , Kingshuk Roy Choudhury

Structures of brain arterial networks (BANs) - that are complex arrangements of individual arteries, their branching patterns, and inter-connectivities - play an important role in characterizing and understanding brain physiology. One would…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Xiaoyang Guo , Aditi Basu Bal , Tom Needham , Anuj Srivastava

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

Neurons and Cognition · Quantitative Biology 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser

At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

In this paper, we present a novel and versatile method to study the dynamics of resting-state fMRI brain connectivity with a high temporal sensitivity. Whereas most existing methods often rely on dividing the time-series into larger…

Neurons and Cognition · Quantitative Biology 2016-01-14 William Hedley Thompson , Peter Fransson

Human brain anatomy and function display a combination of modular and hierarchical organization, suggesting the importance of both cohesive structures and variable resolutions in the facilitation of healthy cognitive processes. However,…

Neurons and Cognition · Quantitative Biology 2015-06-18 Christian Lohse , Danielle S. Bassett , Kelvin O. Lim , Jean M. Carlson

Elucidating the intricate relationship between brain structure and function, both in healthy and pathological conditions, is a key challenge for modern neuroscience. Recent technical and methodological progress in neuroimaging has helped…

Neurons and Cognition · Quantitative Biology 2015-05-01 Ibai Diez , Paolo Bonifazi , Iñaki Escudero , Beatriz Mateos , Miguel A. Muñoz , Sebastiano Stramaglia , Jesus M. Cortes

Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many contact surveys have been conducted to measure changes in human interactions in the face of the pandemic and non-pharmaceutical interventions. These…

Principles of network topology have been widely studied in the human connectome. Of particular interest is the modularity of the human brain, where the connectome is divided into subnetworks and subsequently changes with development, aging…

Neurons and Cognition · Quantitative Biology 2019-02-05 Markus D. Schirmer , Ai Wern Chung , P. Ellen Grant , Natalia S. Rost

This paper introduces a novel, scalable methodology to measure individual perceptions of gaps in mental load -- the cognitive and emotional burden associated with organizing household and childcare tasks -- within heterosexual couples.…

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

Neurons and Cognition · Quantitative Biology 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan
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