English
Related papers

Related papers: Dynamics of a Mathematical Hematopoietic Stem-Cell…

200 papers

We use analytical techniques based on an expansion in the inverse system size to study the stochastic evolutionary dynamics of finite populations of players interacting in a repeated prisoner's dilemma game. We show that a mechanism of…

Populations and Evolution · Quantitative Biology 2012-04-20 Alex J. Bladon , Tobias Galla , Alan J. McKane

We investigate an epidemiological model that incorporates waning of immunity at the individual level and boosting of the immune system upon re-exposure to the pathogen. When immunity is fully restored upon boosting, the system can be…

Dynamical Systems · Mathematics 2025-08-05 Francesca Scarabel , Mónika Polner , Daniel Wylde , Maria Vittoria Barbarossa , Gergely Röst

Double Hopf bifurcation analysis can be used to reveal some complicated dynamical behavior in a dynamical system, such as the existence or coexistence of periodic orbits, quasi-periodic orbits, or even chaos. In this paper, an algorithm for…

Dynamical Systems · Mathematics 2018-11-27 Yanfei Du , Ben Niu , Yuxiao Guo , Junjie Wei

Populations of mammalian stem cells commonly exhibit considerable cell-cell variability. However, the functional role of this diversity is unclear. Here, we analyze expression fluctuations of the stem cell surface marker Sca1 in mouse…

Cell Behavior · Quantitative Biology 2015-10-20 Sonya J. Ridden , Hannah H. Chang , Konstantinos C. Zygalakis , Ben D. MacArthur

In a computational study we reveal a novel dynamical instability of excitation waves in the heartmuscle. The instability manifests itself as gradual local increase in the duration of the actionpotential which causes formation and…

Biological Physics · Physics 2019-08-15 L. D. Weise , A. V. Panfilov

Cell polarization and directional cell migration can display random, persistent and oscillatory dynamic patterns. However, it is not clear if these polarity patterns can be explained by the same underlying regulatory mechanism. Here, we…

Recent progress of symbolic dynamics of one- and especially two-dimensional maps has enabled us to construct symbolic dynamics for systems of ordinary differential equations (ODEs). Numerical study under the guidance of symbolic dynamics is…

chao-dyn · Physics 2009-10-30 Bai-lin Hao , Jun-xian Liu , Wei-mou Zheng

M. Kruskal showed that each nearly-periodic dynamical system admits a formal $U(1)$ symmetry, generated by the so-called roto-rate. We prove that such systems also admit nearly-invariant manifolds of each order, near which rapid…

Dynamical Systems · Mathematics 2021-09-29 J. W. Burby , E. Hirvijoki

We study here the dynamics (and stability) of Probabilistic Population Protocols, via the differential equations approach. We provide a quite general model and we show that it includes the model of Angluin et. al. in the case of very large…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-07-02 Ioannis Chatzigiannakis , Paul G. Spirakis

We consider a class of biologically-motivated stochastic processes in which a unicellular organism divides its resources (volume or damaged proteins, in particular) symmetrically or asymmetrically between its progeny. Assuming the final…

Quantitative Methods · Quantitative Biology 2016-07-20 Andrew Marantan , Ariel Amir

Evolutionary game dynamics are often studied in the context of different population structures. Here we propose a new population structure that is inspired by simple multicellular life forms. In our model, cells reproduce but can stay…

Populations and Evolution · Quantitative Biology 2016-05-26 Kamran Kaveh , Carl Veller , Martin A. Nowak

In this note we prove that a fractional stochastic delay differential equation which satisfies natural regularity conditions generates a continuous random dynamical system on a subspace of a H\"older space which is separable.

Dynamical Systems · Mathematics 2014-01-24 Luu Hoang Duc , Björn Schmalfuss , Stefan Siegmund

We construct stable periodic solutions for a simple form nonlinear delay differential equation (DDE) with a periodic coefficient. The equation involves one underlying nonlinearity with the multiplicative periodic coefficient. The well-known…

Dynamical Systems · Mathematics 2024-02-14 Anatoli Ivanov , Sergiy Shelyag

We study the growth of a periodic pattern in one dimension for a model of spinodal decomposition, the Cahn-Hilliard equation. We particularly focus on the intermediate region, where the non-linearity cannot be negected anymore, and before…

Statistical Mechanics · Physics 2007-05-23 Simon Villain-Guillot , Christophe Josserand

Nonlinear dynamical systems with time delay are abundant in applications, but are notoriously difficult to analyse and predict because delay-induced effects strongly depend on the form of the nonlinearities involved, and on the exact way…

Chaotic Dynamics · Physics 2021-11-03 Natalia B. Janson , Christopher J. Marsden

Athermal disordered systems can exhibit a remarkable response to an applied oscillatory shear: after a relatively few shearing cycles, the system falls into a configuration that had already been visited in a previous cycle. After this point…

Soft Condensed Matter · Physics 2017-08-16 Maxim O. Lavrentovich , Andrea J. Liu , Sidney R. Nagel

The present work revisits the problem of modelling the real gaseous detonation dynamics at the macro-scale by simple steady one-dimensional (1D) models. Experiments of detonations propagating in channels with exponentially expanding…

Fluid Dynamics · Physics 2020-10-21 Qiang Xiao , Matei I. Radulescu

Stem cell heterogeneity is essential for the homeostasis in tissue development. This paper established a general formulation for understanding the dynamics of stem cell regeneration with cell heterogeneity and random transitions of…

Populations and Evolution · Quantitative Biology 2024-07-12 Jinzhi Lei

Collective cell movement, characterized by multiple cells that are in contact for substantial periods of time and undergo correlated motion, plays a central role in cancer and embryogenesis. Recent imaging experiments have provided…

Biological Physics · Physics 2020-06-03 Sumit Sinha , Abdul N Malmi-Kakkada , Xin Li , Himadri S. Samanta , D. Thirumalai

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

Statistical Mechanics · Physics 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden