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In many fields of science, generalized likelihood ratio tests are established tools for statistical inference. At the same time, it has become increasingly common that a simulator (or generative model) is used to describe complex processes…

Applications · Statistics 2016-03-21 Kyle Cranmer , Juan Pavez , Gilles Louppe

Gaussian process (GP) models provide a powerful tool for prediction but are computationally prohibitive using large data sets. In such scenarios, one has to resort to approximate methods. We derive an approximation based on a composite…

Machine Learning · Statistics 2018-02-02 Xiuming Liu , Dave Zachariah , Edith C. H. Ngai

Molecular simulation is a scientific tool dealing with challenges in material science and biology. This is reflected in a permanent development and enhancement of algorithms within scientific simulation packages. Here, we present…

Compared to the wide array of advanced Monte Carlo methods supported by modern probabilistic programming languages (PPLs), PPL support for variational inference (VI) is less developed: users are typically limited to a predefined selection…

Programming Languages · Computer Science 2024-06-25 McCoy R. Becker , Alexander K. Lew , Xiaoyan Wang , Matin Ghavami , Mathieu Huot , Martin C. Rinard , Vikash K. Mansinghka

Basic Parallel Processes (BPPs) are a well-known subclass of Petri Nets. They are the simplest common model of concurrent programs that allows unbounded spawning of processes. In the probabilistic version of BPPs, every process generates…

Logic in Computer Science · Computer Science 2014-01-17 Rémi Bonnet , Stefan Kiefer , Anthony W. Lin

Gaussian Processes (GPs) are widely used tools in statistics, machine learning, robotics, computer vision, and scientific computation. However, despite their popularity, they can be difficult to apply; all but the simplest classification or…

Machine Learning · Computer Science 2016-01-06 Ulrich Schaechtle , Ben Zinberg , Alexey Radul , Kostas Stathis , Vikash K. Mansinghka

Simulator-based models are models for which the likelihood is intractable but simulation of synthetic data is possible. They are often used to describe complex real-world phenomena, and as such can often be misspecified in practice.…

Network design problems constitute an important family of combinatorial optimization problems for which numerous exact and heuristic algorithms have been developed over the last few decades. Two central problems in this family are the…

Optimization and Control · Mathematics 2023-12-19 Eric Larsen , Serge Bisaillon , Jean-François Cordeau , Emma Frejinger

Liesel is a new probabilistic programming framework developed with the aim of supporting research on Bayesian inference based on Markov chain Monte Carlo (MCMC) simulations in general and semi-parametric regression specifications in…

Computation · Statistics 2023-12-01 Hannes Riebl , Paul F. V. Wiemann , Thomas Kneib

This thesis focuses on advancing probabilistic logic programming (PLP), which combines probability theory for uncertainty and logic programming for relations. The thesis aims to extend PLP to support both discrete and continuous random…

Artificial Intelligence · Computer Science 2023-02-13 Nitesh Kumar

We present Sequential Neural Variational Inference (SNVI), an approach to perform Bayesian inference in models with intractable likelihoods. SNVI combines likelihood-estimation (or likelihood-ratio-estimation) with variational inference to…

Machine Learning · Statistics 2022-10-20 Manuel Glöckler , Michael Deistler , Jakob H. Macke

Computer models are used to model complex processes in various disciplines. Often, a key source of uncertainty in the behavior of complex computer models is uncertainty due to unknown model input parameters. Statistical computer model…

Methodology · Statistics 2013-08-02 Won Chang , Murali Haran , Roman Olson , Klaus Keller

In programming by example, users "write" programs by generating a small number of input-output examples and asking the computer to synthesize consistent programs. We consider a challenging problem in this domain: learning regular…

Artificial Intelligence · Computer Science 2018-09-28 Long Ouyang

The location, timing, and abundance of gene expression (both mRNA and proteins) within a tissue define the molecular mechanisms of cell functions. Recent technology breakthroughs in spatial molecular profiling, including imaging-based…

Applications · Statistics 2020-12-10 Qiwei Li , Minzhe Zhang , Yang Xie , Guanghua Xiao

Models defined by stochastic differential equations (SDEs) allow for the representation of random variability in dynamical systems. The relevance of this class of models is growing in many applied research areas and is already a standard…

Methodology · Statistics 2014-08-06 Umberto Picchini

Is it possible to make statistical inference broadly accessible to non-statisticians without sacrificing mathematical rigor or inference quality? This paper describes BayesDB, a probabilistic programming platform that aims to enable users…

Artificial Intelligence · Computer Science 2015-12-17 Vikash Mansinghka , Richard Tibbetts , Jay Baxter , Pat Shafto , Baxter Eaves

Simulation-Based Inference (SBI) is a common name for an emerging family of approaches that infer the model parameters when the likelihood is intractable. Existing SBI methods either approximate the likelihood, such as Approximate Bayesian…

Machine Learning · Computer Science 2023-11-29 Theo Gruner , Boris Belousov , Fabio Muratore , Daniel Palenicek , Jan Peters

Recursive calls over recursive data are useful for generating probability distributions, and probabilistic programming allows computations over these distributions to be expressed in a modular and intuitive way. Exact inference is also…

Programming Languages · Computer Science 2023-03-28 David Chiang , Colin McDonald , Chung-chieh Shan

Probabilistic inference is fundamentally hard, yet many tasks require optimization on top of inference, which is even harder. We present a new optimization-via-compilation strategy to scalably solve a certain class of such problems. In…

Programming Languages · Computer Science 2025-04-11 Minsung Cho , John Gouwar , Steven Holtzen

We develop operators for construction of proposals in probabilistic programs, which we refer to as inference combinators. Inference combinators define a grammar over importance samplers that compose primitive operations such as application…

Machine Learning · Statistics 2021-06-18 Sam Stites , Heiko Zimmermann , Hao Wu , Eli Sennesh , Jan-Willem van de Meent