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The diversity of the immune repertoire is initially generated by random rearrangements of the receptor gene during early T and B cell development. Rearrangement scenarios are composed of random events -- choices of gene templates, base pair…

Genomics · Quantitative Biology 2016-06-29 Yuval Elhanati , Quentin Marcou , Thierry Mora , Aleksandra M. Walczak

A partial differential equation is derived, describing the replicator dynamics with mutations of games with a continuous strategy space. This equation is then applied to continuous versions of symmetric 2x2 games, such as the Prisoners…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 M. Ruijgrok , T. W. Ruijgrok

Well-calibrated probabilistic regression models are a crucial learning component in robotics applications as datasets grow rapidly and tasks become more complex. Unfortunately, classical regression models are usually either probabilistic…

Machine Learning · Computer Science 2023-09-12 Hany Abdulsamad , Peter Nickl , Pascal Klink , Jan Peters

Hidden Markov Models, HMM's, are mathematical models of Markov processes with state that is hidden, but from which information can leak. They are typically represented as 3-way joint-probability distributions. We use HMM's as denotations of…

Logic in Computer Science · Computer Science 2023-06-22 Annabelle McIver , Carroll Morgan , Tahiry Rabehaja

We present two variants of a multi-agent reinforcement learning algorithm based on evolutionary game theoretic considerations. The intentional simplicity of one variant enables us to prove results on its relationship to a system of ordinary…

Machine Learning · Computer Science 2024-05-29 Johann Bauer , Sheldon West , Eduardo Alonso , Mark Broom

We consider a quantum particle, moving on a lattice with a tight-binding Hamiltonian, which is subjected to measurements to detect it's arrival at a particular chosen set of sites. The projective measurements are made at regular time…

Quantum Physics · Physics 2015-06-19 Shrabanti Dhar , Subinay Dasgupta , Abhishek Dhar , Diptiman Sen

Under constant selection, each trait has a fixed fitness, and small mutation rates allow populations to efficiently exploit the optimal trait. Therefore it is reasonable to expect mutation rates will evolve downwards. However, we find this…

Populations and Evolution · Quantitative Biology 2022-08-23 Brian Mintz , Feng Fu

Neuroscientists have long criticised deep learning algorithms as incompatible with current knowledge of neurobiology. We explore more biologically plausible versions of deep representation learning, focusing here mostly on unsupervised…

Machine Learning · Computer Science 2016-08-10 Yoshua Bengio , Dong-Hyun Lee , Jorg Bornschein , Thomas Mesnard , Zhouhan Lin

Extending classical probabilistic reasoning using the quantum mechanical view of probability has been of recent interest, particularly in the development of hidden quantum Markov models (HQMMs) to model stochastic processes. However, there…

Machine Learning · Computer Science 2019-12-05 Sandesh Adhikary , Siddarth Srinivasan , Geoff Gordon , Byron Boots

This contribution is concerned with mathematical models for the dynamics of the genetic composition of populations evolving under recombination. Recombination is the genetic mechanism by which two parent individuals create the mixed type of…

Populations and Evolution · Quantitative Biology 2011-01-12 Ellen Baake

Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analysis. Improved understanding of these clusters is of utmost importance,…

Machine Learning · Computer Science 2010-01-25 Tomáš Vinař , Broňa Brejová , Giltae Song , Adam Siepel

Psychological change processes, such as university student dropout in math, often exhibit discrete latent state transitions and can be studied using regime-switching models with intensive longitudinal data (ILD). Recently, regime-switching…

Methodology · Statistics 2025-12-23 Kento Okuyama , Tim Fabian Schaffland , Pascal Kilian , Holger Brandt , Augustin Kelava

Probabilistic programming is related to a compositional approach to stochastic modeling by switching from discrete to continuous time dynamics. In continuous time, an operator-algebra semantics is available in which processes proceeding in…

Artificial Intelligence · Computer Science 2012-12-05 Eric Mjolsness

There is a large body of evidence that decision makers frequently depart from Bayesian updating. This paper introduces a model, robust maximum likelihood (RML) updating, where deviations from Bayesian updating are due to multiple…

Theoretical Economics · Economics 2025-12-17 Elchin Suleymanov

Hidden Markov Models (HMMs) are one of the most fundamental and widely used statistical tools for modeling discrete time series. In general, learning HMMs from data is computationally hard (under cryptographic assumptions), and…

Machine Learning · Computer Science 2012-07-10 Daniel Hsu , Sham M. Kakade , Tong Zhang

The deterministic dynamics of randomly connected neural networks are studied, where a state of binary neurons evolves according to a discreet-time synchronous update rule. We give a theoretical support that the overlap of systems' states…

Statistical Mechanics · Physics 2015-03-10 Taro Toyoizumi , Haiping Huang

In this paper, we study the existence and the property of the Hopf bifurcation in the two-strategy replicator dynamics with distributed delays. In evolutionary games, we assume that a strategy would take an uncertain time delay to have a…

Systems and Control · Computer Science 2017-03-21 Nesrine Ben Khalifa , Rachid El Azouzi , Yezekael Hayel

The evolution of two species with different fitness is investigated on degree-heterogeneous graphs. The population evolves either by one individual dying and being replaced by the offspring of a random neighbor (voter model (VM) dynamics)…

Populations and Evolution · Quantitative Biology 2009-11-13 T. Antal , S. Redner , V. Sood

We address the problem of analyzing sets of noisy time-varying signals that all report on the same process but confound straightforward analyses due to complex inter-signal heterogeneities and measurement artifacts. In particular we…

Industrial processes generate a massive amount of monitoring data that can be exploited to uncover hidden time losses in the system. This can be used to enhance the accuracy of maintenance policies and increase the effectiveness of the…

Applications · Statistics 2025-08-27 Fernando Miguelez , Josu Doncel , Maria Dolores Ugarte