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Reactive chemistry of molecular hydrogen at surfaces, notably dissociative sticking and hydrogen evolution, plays a crucial role in energy storage and fuel cells. Theoretical studies can help to decipher underlying mechanisms and reaction…

Accurately predicting chemical reactions is essential for driving innovation in synthetic chemistry, with broad applications in medicine, manufacturing, and agriculture. At the same time, reaction prediction is a complex problem which can…

Machine Learning · Computer Science 2025-04-23 Ryan J. Miller , Alexander E. Dashuta , Brayden Rudisill , David Van Vranken , Pierre Baldi

The theory of representation learning aims to build methods that provably invert the data generating process with minimal domain knowledge or any source of supervision. Most prior approaches require strong distributional assumptions on the…

Machine Learning · Computer Science 2022-06-03 Kartik Ahuja , Jason Hartford , Yoshua Bengio

Describing chemical reactions in solution on a molecular level is a challenging task due to the high mobility of weakly interacting solvent molecules which requires configurational sampling. For instance, polar and protic solvents can…

Chemical Physics · Physics 2025-10-22 Paul L. Türtscher , Markus Reiher

A sustainable burn platform through inertial confinement fusion (ICF) has been an ongoing challenge for over 50 years. Mitigating engineering limitations and improving the current design involves an understanding of the complex coupling of…

We propose a unified framework that allows for the full mechanistic reconstruction of chemical reaction networks (CRNs) from concentration data. The framework utilizes an integral formulation of the differential equations governing the…

Numerical Analysis · Mathematics 2026-02-13 Abraham Reyes-Velazquez , Stefan Güttel , Igor Larrosa , Jonas Latz

We consider stochastic reaction networks modeled by continuous-time Markov chains. Such reaction networks often contain many reactions, potentially occurring at different time scales, and have unknown parameters (kinetic rates, total…

Probability · Mathematics 2023-02-20 Linard Hoessly , Carsten Wiuf

We demonstrate a machine learning approach designed to extract hidden chemistry/physics to facilitate new materials discovery. In particular, we propose a novel method for learning latent knowledge from material structure data in which…

Materials Science · Physics 2021-08-03 Tien-Cuong Nguyen , Van-Quyen Nguyen , Van-Linh Ngo , Quang-Khoat Than , Tien-Lam Pham

Transformer architectures have achieved remarkable success across language, vision, and multimodal tasks, and there is growing demand for them to address in-context compositional learning tasks. In these tasks, models solve the target…

Machine Learning · Computer Science 2025-11-26 Wei Chen , Jingxi Yu , Zichen Miao , Qiang Qiu

Information thermodynamics relates the rate of change of mutual information between two interacting subsystems to their thermodynamics when the joined system is described by a bipartite stochastic dynamics satisfying local detailed balance.…

Statistical Mechanics · Physics 2022-08-05 Emanuele Penocchio , Francesco Avanzini , Massimiliano Esposito

Causal discovery is challenging in general dynamical systems because, without strong structural assumptions, the underlying causal graph may not be identifiable even from interventional data. However, many real-world systems exhibit…

Machine Learning · Computer Science 2026-04-07 Panayiotis Panayiotou , Özgür Şimşek

Stochastic evolution of Chemical Reactions Networks (CRNs) over time is usually analysed through solving the Chemical Master Equation (CME) or performing extensive simulations. Analysing stochasticity is often needed, particularly when some…

Logic in Computer Science · Computer Science 2015-09-11 Luca Laurenti , Luca Cardelli , Marta Kwiatkowska

Classification methods based on sparse estimation have drawn much attention recently, due to their effectiveness in processing high-dimensional data such as images. In this paper, a method to improve the performance of a sparse…

Machine Learning · Statistics 2018-10-24 Babak Barazandeh , Mohammadhussein Rafieisakhaei , Sunwook Kim , Zhenyu , Kong , Maury A. Nussbaum

A new line of research for feature selection based on neural networks has recently emerged. Despite its superiority to classical methods, it requires many training iterations to converge and detect informative features. The computational…

Machine Learning · Computer Science 2022-11-29 Ghada Sokar , Zahra Atashgahi , Mykola Pechenizkiy , Decebal Constantin Mocanu

Recent advances in deep learning highlight the need for personalized models that can learn from small samples, handle high-dimensional features, and remain interpretable. To address this, we propose the Sparse Deep Additive Model with…

Machine Learning · Statistics 2026-05-19 Yi-Ting Hung , Li-Hsiang Lin , Vince D. Calhoun

Motivation: A Chemical Reaction Network (CRN) is a set of chemical reactions, which can be very complex and difficult to analyze. Indeed, dynamical properties of CRNs can be described by a set of non-linear differential equations that…

Computational Engineering, Finance, and Science · Computer Science 2021-07-02 Lucia Nasti , Roberta Gori , Paolo Milazzo , Federico Poloni

We outline a machine learning strategy for determining the effective interaction in the condensed phases of matter using scattering. Via a case study of colloidal suspensions, we showed that the effective potential can be probabilistically…

Soft Condensed Matter · Physics 2021-03-30 Chi-Huan Tung , Shou-Yi Chang , Jan-Michael Carrillo , Bobby G. Sumpter , Changwoo Do , Wei-Ren Chen

Sensitivity analysis of biochemical reactions aims at quantifying the dependence of the reaction dynamics on the reaction rates. The computation of the parameter sensitivities, however, poses many computational challenges when taking…

Molecular Networks · Quantitative Biology 2018-11-07 Vo Hong Thanh , Roberto Zunino , Corrado Priami

Modeling complex spatiotemporal dynamical systems, such as the reaction-diffusion processes, have largely relied on partial differential equations (PDEs). However, due to insufficient prior knowledge on some under-explored dynamical…

Machine Learning · Computer Science 2023-05-23 Chengping Rao , Pu Ren , Qi Wang , Oral Buyukozturk , Hao Sun , Yang Liu

Raman spectroscopy is an effective, low-cost, non-intrusive technique often used for chemical identification. Typical approaches are based on matching observations to a reference database, which requires careful preprocessing, or supervised…

Machine Learning · Computer Science 2022-10-12 Bo Li , Mikkel N. Schmidt , Tommy S. Alstrøm