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Voltage-gated ion channels mediate electrical excitability of cellular membranes. Reduced models of the voltage sensor (VS) of Kv channels produce insight into the electrostatic physics underlying the response of the highly positively…

Biomolecules · Quantitative Biology 2015-03-13 Alexander Peyser

Electrical signaling via voltage-gated ion channels depends upon the function of a voltage sensor (VS), identified with the S1-S4 domain in voltage-gated K+ channels. Here we investigate some energetic aspects of the sliding-helix model of…

Biomolecules · Quantitative Biology 2019-01-18 Alexander Peyser , Wolfgang Nonner

Electrical signaling via voltage-gated ion channels depends upon the function of the voltage sensor (VS), identified with the S1-S4 domain of voltage-gated K channels. Here we investigate some physical aspects of the sliding-helix model of…

Biomolecules · Quantitative Biology 2015-03-13 Alexander Peyser , Wolfgang Nonner

We performed density functional studies of electronic properties and mechanisms of hydrogen transport in Rb3H(SeO4)2 crystal which represents technologically promising class M3H(XO4)2 of proton conductors (M=Rb,Cs, NH4; X=S,Se). The…

Statistical Mechanics · Physics 2015-03-13 N. Pavlenko , A. Pietraszko , A. Pawlowski , M. Polomska , I. V. Stasyuk , B. Hilczer

An intense controversy has surrounded the mechanism of voltage-gating in ion channels. We interpreted the two leading models of voltage-gating with respect to the thermodynamic energetics of membrane insertion of the voltage-sensing…

Biomolecules · Quantitative Biology 2011-04-21 Ashok Palaniappan

The internal image of the proton is unveiled by examining the generalized parton distributions (GPDs) at zero skewness, within the basis light-front quantized environment. Several distributions emerge when a quark is sampled with different…

High Energy Physics - Phenomenology · Physics 2024-01-23 Satvir Kaur , Siqi Xu , Chandan Mondal , Xingbo Zhao , James P. Vary

We investigate transient transport of electrons through a single-quantum-dot controlled by a plunger gate. The dot is embedded in a finite wire that is weakly coupled to leads and strongly coupled to a single cavity photon mode. A…

Mesoscale and Nanoscale Physics · Physics 2013-11-15 Nzar Rauf Abdullah , Chi-Shung Tang , Andrei Manolescu , Vidar Gudmundsson

Standard models of ion channel voltage gating require substantial movement of one transmembrane segment, S4, of the voltage sensing domain. Evidence comes from the accessibility to external methanethiosulfonate (MTS) reagents of the…

Biomolecules · Quantitative Biology 2013-09-06 Alisher M. Kariev , Michael E. Green

Theoretical and experimental evidences support the hypothesis that extremely low-frequency electromagnetic fields can affect voltage-gated channels. Little is known, however, about their effect on potassium channels. Kv1.3, a member of the…

Subcellular Processes · Quantitative Biology 2015-08-26 Claudia Cecchetto , Marta Maschietto , Pasquale Boccaccio , Stefano Vassanelli

We report on the fabrication and electronic transport characterisation of Schottky-gated strongly confined Si/SiGe quantum point contacts (QPC). At zero magnetic field and T=450mK the QPC conductance as a function of gate voltage shows a…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 G. Scappucci , L. Di Gaspare , E. Giovine , A. Notargiacomo , R. Leoni , F. Evangelisti

An exact solution is presented for tunneling through a negative-U d-fold degenerate molecular quantum dot weakly coupled to electrical leads. The tunnel current exhibits hysteresis if the level degeneracy of the negative-U dot is larger…

Mesoscale and Nanoscale Physics · Physics 2009-11-07 A. S. Alexandrov , A. M. Bratkovsky , R. S. Williams

Gateable semiconductor quantum dots (QDs) provide a versatile platform for analog quantum simulations of electronic many-body systems. In particular, QD arrays offer a natural representation of the interacting $\pi$-electron system of small…

Mesoscale and Nanoscale Physics · Physics 2026-05-05 Cecilie Hermansen , Mara Caltapanides , Volker Meden , Jens Paaske

Ge/SiGe quantum well heterostructures confining a high-mobility two-dimensional hole gas (2DHG) have emerged as a compelling platform for hybrid superconductor(S)-semiconductor(Sm) quantum devices. Here, we investigate the low-temperature…

We study the low-temperature transport properties of the systems of parallel quantum dots described by the N-impurity Anderson model. We calculate the quasiparticle scattering phase shifts, spectral functions and correlations as a function…

Mesoscale and Nanoscale Physics · Physics 2009-03-05 Rok Zitko , Janez Bonca

The four-electron oxygen reduction reaction on Pt catalyst in alkaline solution undergoes proton transfer via tunneling mechanism. The hydrogen/deuterium kinetic isotopic rate constant ratio (kH/kD ) = 32 in a low overpotential region,…

Chemical Physics · Physics 2018-12-10 Ken Sakaushi , Andrey Lyalin , Tetsuya Taketsugu , Kohei Uosaki

Hydrated excess protons under hydrophobic confinement are a critical component of charge transport behavior and reactivity in nanoporous materials and biomolecular systems. Herein excess proton confinement effects are computationally…

Soft Condensed Matter · Physics 2020-06-04 Xinyou Ma , Chenghan Li , Alex B. F. Martinson , Gregory A. Voth

Many voltage-gated potassium (Kv) channels display a time-dependent phenomenon called C-type inactivation, whereby prolonged activation by voltage leads to the inhibition of ionic conduction, a process that involves a conformational change…

The potential energy surface of the H13 proton in base cytosine of the DNA molecules is calculated {\it ab initio} at the Gaussian98 MP2/6-311G(d,p) level. Two potential wells are found. One corresponds to the normal cytosine, while the…

Biological Physics · Physics 2009-11-11 Zhen-Min Zhao , Qi-Ren Zhang , Chun-Yuan Gao , Yi-Zhong Zhuo

We present a detailed study of the surface acoustic wave mediated quantized transport of electrons through a split gate device containing an impurity potential defined quantum dot within the split gate channel. A new regime of quantized…

Mesoscale and Nanoscale Physics · Physics 2009-11-10 N. E. Fletcher , J. Ebbecke , T. J. B. M. Janssen , F. J. Ahlers , M. Pepper , H. E. Beere , D. A. Ritchie

A numerically exact calculation of the T=0 transport properties of a quantum wire interacting with a lateral two-level quantum dot is presented. The wire conductance is calculated for all different states of charge and spin of the quantum…

Strongly Correlated Electrons · Physics 2007-05-23 Maria A. Davidovich , E. V. Anda , C. A. Busser , G. Chiappe
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