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Understanding control mechanisms in biological systems plays a crucial role in important applications, for instance in cell reprogramming. Boolean modeling allows the identification of possible efficient strategies, helping to reduce the…

Molecular Networks · Quantitative Biology 2021-12-21 Laura Cifuentes-Fontanals , Elisa Tonello , Heike Siebert

We consider the problem of identifying the most influential nodes for a spreading process on a network when prior knowledge about structure and dynamics of the system is incomplete or erroneous. Specifically, we perform a numerical analysis…

Physics and Society · Physics 2018-10-09 Şirag Erkol , Ali Faqeeh , Filippo Radicchi

Discrete dynamic models are a powerful tool for the understanding and modeling of large biological networks. Although a lot of progress has been made in developing analysis tools for these models, there is still a need to find approaches…

Molecular Networks · Quantitative Biology 2013-06-14 Jorge G. T. Zañudo , Réka Albert

Boolean networks are discrete dynamical systems in which the state (zero or one) of each node is updated at each time t to a state determined by the states at time t-1 of those nodes that have links to it. When these systems are used to…

Molecular Networks · Quantitative Biology 2012-02-28 Andrew Pomerance , Michelle Girvan , Ed Ott

Complex diseases can be modeled as damage to intracellular networks that results in abnormal cell behaviors. Network-based dynamic models such as Boolean models have been employed to model a variety of biological systems including those…

Biological Physics · Physics 2016-12-30 Gang Yang , Colin Campbell , Réka Albert

Boolean Networks have been used to study numerous phenomena, including gene regulation, neural networks, social interactions, and biological evolution. Here, we propose a general method for determining the critical behavior of Boolean…

Disordered Systems and Neural Networks · Physics 2009-11-11 Andre A. Moreira , Luis A. N. Amaral

One of the characteristic features of genetic networks is their inherent robustness, that is, their ability to retain functionality in spite of the introduction of random errors. In this paper, we seek to better understand how robustness is…

Molecular Networks · Quantitative Biology 2009-04-29 Arnab Bhattacharyya , Bernhard Haeupler

The functions of complex networks are usually determined by a small set of vital nodes. Finding the best set of vital nodes (eigenshield nodes) is critical to the network's robustness against rumor spreading and cascading failures, which…

Data Analysis, Statistics and Probability · Physics 2022-10-31 Ming-Yang Zhou , Manuel Sebastian Mariani , Hao Liao , Rui Mao , Yi-Cheng Zhang

We investigate the propagation of perturbations in Boolean networks by evaluating the Derrida plot and modifications of it. We show that even small Random Boolean Networks agree well with the predictions of the annealed approximation, but…

Statistical Mechanics · Physics 2009-05-06 Christoph Fretter , Agnes Szejka , Barbara Drossel

The theory of complex networks and of disordered systems is used to study the stability and dynamical properties of a simple model of material flow networks defined on random graphs. In particular we address instabilities that are…

Disordered Systems and Neural Networks · Physics 2009-11-13 Kartik Anand , Tobias Galla

The network of networks(NON) research is focused on studying the properties of n interdependent networks which is ubiquitous in the real world. Identifying the influential nodes in the network of networks is theoretical and practical…

Social and Information Networks · Computer Science 2015-01-26 Meizhu Li , Qi Zhang , Qi Liu , Yong Deng

Dynamical entities interacting with each other on complex networks often exhibit multistability. The stability of a desired steady regime (e.g., a synchronized state) to large perturbations is critical in the operation of many real-world…

Chaotic Dynamics · Physics 2017-03-22 Chiranjit Mitra , Anshul Choudhary , Sudeshna Sinha , Jürgen Kurths , Reik V. Donner

Social networks play an important role in analyzing the impact of individual-level interactions on societal or economic outcomes. We model interactive decision making for a community of individuals with different traits, represented by a…

Physics and Society · Physics 2022-08-09 Pengyu Liu , Jie Jian

We consider the problem of maximizing the spread of influence in a social network by choosing a fixed number of initial seeds --- a central problem in the study of network cascades. The majority of existing work on this problem, formally…

Social and Information Networks · Computer Science 2016-09-22 Rico Angell , Grant Schoenebeck

The harmonic influence is a measure of the importance of nodes in social networks, which can be approximately computed by a distributed message-passing algorithm. In this extended abstract we look at two open questions about this algorithm.…

Optimization and Control · Mathematics 2018-04-20 Wilbert Samuel Rossi , Paolo Frasca

Understanding the network structure, and finding out the influential nodes is a challenging issue in the large networks. Identifying the most influential nodes in the network can be useful in many applications like immunization of nodes in…

Social and Information Networks · Computer Science 2017-01-10 Naveen Gupta , Anurag Singh , Hocine Cherifi

Boolean networks constitute relevant mathematical models to study the behaviours of genetic and signalling networks. These networks define regulatory influences between molecular nodes, each being associated to a Boolean variable and a…

Discrete Mathematics · Computer Science 2025-06-24 José E. R. Cury , Patrícia Tenera Roxo , Vasco Manquinho , Claudine Chaouiya , Pedro T. Monteiro

The complex dynamics of gene expression in living cells can be well-approximated using Boolean networks. The average sensitivity is a natural measure of stability in these systems: values below one indicate typically stable dynamics…

Molecular Networks · Quantitative Biology 2018-10-03 Bryan C. Daniels , Hyunju Kim , Douglas Moore , Siyu Zhou , Harrison Smith , Bradley Karas , Stuart A. Kauffman , Sara I. Walker

The network paradigm is used to gain insight into the structural root causes of the resilience of consensus in dynamic collective behaviors, and to analyze the controllability of the swarm dynamics. Here we devise the dynamic signaling…

Physics and Society · Physics 2014-01-14 Mohammad Komareji , Roland Bouffanais

The problem of finding clusters in complex networks has been extensively studied by mathematicians, computer scientists and, more recently, by physicists. Many of the existing algorithms partition a network into clear clusters, without…

Disordered Systems and Neural Networks · Physics 2009-11-11 David Gfeller , Jean-Cédric Chappelier , Paolo De Los Rios