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Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to…
High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…
Current spectroscopic optical coherence tomography (OCT) methods rely on a posteriori numerical calculation. We present an alternative for accessing optically the spectroscopic information in OCT, i.e. without any post-processing, by using…
We demonstrate that simultaneous application of optical clearing agents (OCAs) and complex wavefront shaping in optical coherence tomography (OCT) can provide significant enhancement of the penetration depth and imaging quality. OCA reduces…
Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…
Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…
On-invasive optical imaging techniques are essential diagnostic tools in many fields. Although various recent methods have been proposed to utilize and control light in multiple scattering media, non-invasive optical imaging through and…
The development of optical nanofibers (ONF) and the study and control of their optical properties when coupling atoms to their electromagnetic modes has opened new possibilities for their use in quantum optics and quantum information…
We present a finite difference time domain (FDTD) model for computation of A line scans in time domain optical coherence tomography (OCT). By simulating only the end of the two arms of the interferometer and computing the interference…
Orbital angular momentum (OAM) recognition of vortex beams is critical for applications ranging from optical communications to quantum technologies. However, conventional approaches designed for free-space propagation struggle when light…
Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…
We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…
While scattered light conveys most of the information we perceive, scattering may also distort that information before it reaches our detectors. The problem is acute in many applications, such as in high-resolution microscopy of biological…
Automatic and accurate segmentation for retinal and choroidal layers of Optical Coherence Tomography (OCT) is crucial for detection of various ocular diseases. However, because of the variations in different equipments, OCT data obtained…
We apply three optical coherence tomography (OCT) image analysis techniques to extract morphometric information from OCT images obtained on peripheral nerves of rat. The accuracy of each technique is evaluated against histological…
Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital…
Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…
Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…
Quantum Optical Coherence Tomography (Q-OCT) presents many advantages over its classical counterpart, Optical Coherence Tomography (OCT): it provides an increased axial resolution and is immune to even orders of dispersion. The core of…
Optical diffraction tomography (ODT) is a powerful non-invasive 3D imaging technique, but its combination with broadband light sources is difficult. In this study, we introduce ultrabroadband ODT, covering over 150 nm of visible spectral…