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Nowadays, additive manufacturing processes greatly simplify the production of openwork workpiece providing new opportunities for workpieces design. Based on Nature knowledge, a new bio-inspired workpiece structural optimization approach is…

Medical Physics · Physics 2018-10-29 Clement Audibert , Julien Chaves-Jacob , Jean-Marc Linares , Quentin-Alexis Lopez

In general, there is a mismatch between a finite element model {(FEM)} of a structure and its real behaviour. In aeronautics, this mismatch must be small because {FEM}s are a fundamental part of the development of an aircraft and of…

Computational Engineering, Finance, and Science · Computer Science 2026-04-20 Gabriele Dessena , Alessandro Pontillo , Dmitry I. Ignatyev , James F. Whidborne , Luca Zanotti Fragonara

Topology optimization of microstructures plays a critical role in optimizing functional performance across diverse engineering applications. While metamaterials with enhanced mechanical properties -- such as hyperelasticity, energy…

Soft Condensed Matter · Physics 2025-01-27 Weiming Wang , Yanhao Hou , Renbo Su , Weiguang Wang , Charlie C. L. Wang

Statistical shape analysis of slabular objects like groups of hippocampi is highly useful for medical researchers as it can be useful for diagnoses and understanding diseases. This work proposes a novel object representation based on…

Methodology · Statistics 2024-09-09 Mohsen Taheri , Stephen M. Pizer , Jörn Schulz

A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite…

Tissues and Organs · Quantitative Biology 2017-09-06 Shuji Ishihara , Philippe Marcq , Kaoru Sugimura

A non-isothermal phase field model that captures both displacive and diffusive phase transformations in a unified framework is presented. The model is developed in a formal thermodynamic setting, which provides guidance on admissible…

Materials Science · Physics 2011-12-02 Mirko Maraldi , Garth N. Wells , Luisa Molari

The optimization of porous infill structures via local volume constraints has become a popular approach in topology optimization. In some design settings, however, the iterative optimization process converges only slowly, or not at all even…

Computational Engineering, Finance, and Science · Computer Science 2022-03-22 Junpeng Wang , Jun Wu , Rüdiger Westermann

Cochlear implantation is currently the most effective treatment for patients with severe deafness, but mastering cochlear implantation is extremely challenging because the temporal bone has extremely complex and small three-dimensional…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Xin Hua , Zhijiang Du , Hongjian Yu , Jixin Ma , Fanjun Zheng , Cheng Zhang , Qiaohui Lu , Hui Zhao

This work investigates a two-stage method for constructing projection-based reduced-order models (ROMs) of parameterized partial differential equations (PDEs). Based on established tensorial ROM methodology, the proposed approach reduces…

Numerical Analysis · Mathematics 2026-04-30 Arjun Vijaywargia , Eric C. Cyr , Anthony Gruber

The mechanical behaviour of solid biological tissues has long been described using models based on classical continuum mechanics. However, the classical continuum theories of elasticity and viscoelasticity cannot easily capture the…

Biological Physics · Physics 2017-05-16 Shakti N. Menon , Cameron L. Hall , Scott W. McCue , D. L. Sean McElwain

We study equilibrium shapes and shape transformations of a confined semiflexible chain inside a soft lipid tubule using simulations and continuum theories. The deformed tubular shapes and chain conformations depend on the relative magnitude…

Soft Condensed Matter · Physics 2020-06-11 Subhadip Biswas , Buddhapriya Chakrabarti

Bone remodelling maintains the functionality of skeletal tissue by locally coordinating bone-resorbing cells (osteoclasts) and bone-forming cells (osteoblasts) in the form of Bone Multicellular Units (BMUs). Understanding the emergence of…

Tissues and Organs · Quantitative Biology 2011-05-26 Pascal R Buenzli , Peter Pivonka , David W Smith

In recent decades, the main focus of computer modeling has been on supporting the design and development of engineering prototyes, but it is now ubiquitous in non-traditional areas such as medical rehabilitation. Conventional modeling…

Machine Learning · Computer Science 2024-09-13 Jonas Kneifl , David Rosin , Oliver Röhrle , Jörg Fehr

We devise a generalization of tree approximation that generates conforming meshes, i.e., meshes with a particular structure like edge-to-edge triangulations. A key feature of this generalization is that the choices of the cells to be…

Numerical Analysis · Mathematics 2023-01-26 Peter Binev , Francesca Fierro , Andreas Veeser

A micromorphic computational homogenization framework has recently been developed to deal with materials showing long-range correlated interactions, i.e. displaying patterning modes. Typical examples of such materials are elastomeric…

Soft Condensed Matter · Physics 2024-06-21 S. Maraghechi , O. Rokoš , R. H. J. Peerlings , M. G. D. Geers , J. P. M. Hoefnagels

Phase-field fracture models are known to overestimate the crack area, a discrepancy that compromises the accuracy of fracture predictions. This issue stems from the diffuse crack representation and numerical artifacts, such as strain…

Materials Science · Physics 2026-05-06 M. Castillón , J. Segurado , I. Romero

This work addresses an efficient Global-Local approach supplemented with predictor-corrector adaptivity applied to anisotropic phase-field brittle fracture. The phase-field formulation is used to resolve the sharp crack surface topology on…

Numerical Analysis · Mathematics 2020-02-19 Nima Noii , Fadi Aldakheel , Thomas Wick , Peter Wriggers

Thin-plate splines can be used for interpolation of image values, but can also be used to represent a smooth surface, such as the boundary between two structures. We present a method for partitioning vertebra segmentation masks into two…

Image and Video Processing · Electrical Eng. & Systems 2019-07-27 Nikolas Lessmann , Jelmer M. Wolterink , Majd Zreik , Max A. Viergever , Bram van Ginneken , Ivana Išgum

Structured illumination enables the tailoring of an imaging device's optical transfer function to enhance resolution. We propose the incorporation of a temporal periodic modulation, specifically a rotating mask, to encode multiple transfer…

Optics · Physics 2023-06-27 Guillaume Noetinger , Fabrice Lemoult , Sébastien M. Popoff

Purpose: Conventional MRI is relying on the assumption of the magnetic field being homogeneous in direction and amplitude. However, with the growing interest in portable, affordable point-of-care MRI systems, these assumptions do not…

Medical Physics · Physics 2026-02-17 Fabian Bschorr , Thomas Hüfken , Tobias Lobmeyer , Volker Rasche