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The R package (R Core Team (2016)) genMOSS is specifically designed for the Bayesian analysis of genome-wide association study data. The package implements the mode oriented stochastic search (MOSS) procedure as well as a simple moving…

Computation · Statistics 2016-11-24 Matthew Friedlander , Adrian Dobra , Helene Massam , Laurent Briollais

This paper proposes a new topology optimization method that applies a convolutional neural network (CNN), which is one deep learning technique for topology optimization problems. Using this method, we acquire a structure with a little…

Machine Learning · Computer Science 2020-01-06 Yusuke Takahashi , Yoshiro Suzuki , Akira Todoroki

Sequence comparison and alignment has had an enormous impact on our understanding of evolution, biology, and disease. Comparison and alignment of biological networks will likely have a similar impact. Existing network alignments use…

Molecular Networks · Quantitative Biology 2009-10-08 Oleksii Kuchaiev , Tijana Milenkovic , Vesna Memisevic , Wayne Hayes , Natasa Przulj

Background. Dynamical models of gene regulatory networks (GRNs) are highly effective in describing complex biological phenomena and processes, such as cell differentiation and cancer development. Yet, the topological and functional…

Molecular Networks · Quantitative Biology 2015-08-17 Andrea Paroni , Alex Graudenzi , Giulio Caravagna , Chiara Damiani , Giancarlo Mauri , Marco Antoniotti

Identifying individuals who are at high risk of cancer due to inherited germline mutations is critical for effective implementation of personalized prevention strategies. Most existing models to identify these individuals focus on specific…

This paper introduces an adaptive convolutional neural network (CNN) architecture capable of automating various topology optimization (TO) problems with diverse underlying physics. The proposed architecture has an encoder-decoder-type…

Computational Engineering, Finance, and Science · Computer Science 2024-04-19 Khaish Singh Chadha , Prabhat Kumar

Revealing the structural features of a complex system from the observed collective dynamics is a fundamental problem in network science. In order to compute the various topological descriptors commonly used to characterize the structure of…

Data Analysis, Statistics and Probability · Physics 2021-02-16 Sebastian Raimondo , Manlio De Domenico

Meta-analysis methods are used to combine evidence from multiple studies. Meta-regression as well as model-based meta-analysis are extensions of standard pairwise meta-analysis in which information about study-level covariates and…

Methodology · Statistics 2022-02-02 Burak Kürsad Günhan , Christian Röver , Tim Friede

We revisit the effectiveness of topological descriptors for molecular graph classification and design a simple, yet strong baseline. We demonstrate that a simple approach to feature engineering - employing histogram aggregation of edge…

Machine Learning · Computer Science 2024-07-24 Jakub Adamczyk , Wojciech Czech

We present `latentcor`, an R package for correlation estimation from data with mixed variable types. Mixed variables types, including continuous, binary, ordinal, zero-inflated, or truncated data are routinely collected in many areas of…

Computation · Statistics 2022-04-22 Mingze Huang , Christian L. Müller , Irina Gaynanova

In edge inference, wireless resource allocation and accelerator-level deep neural network (DNN) scheduling have yet to be co-optimized in an end-to-end manner. The lack of coordination between wireless transmission and accelerator-level DNN…

Signal Processing · Electrical Eng. & Systems 2026-03-03 Sai Xu , Kai-Kit Wong , Yanan Du , Hyundong Shin

We develop a statistical theory to characterize correlations in weighted networks. We define the appropriate metrics quantifying correlations and show that strictly uncorrelated weighted networks do not exist due to the presence of…

Disordered Systems and Neural Networks · Physics 2009-11-11 M. Angeles Serrano , Marian Boguna , Romualdo Pastor-Satorras

Background: Time-to-event data with multiple time scales are observed in many epidemiological and clinical studies. While models that allow for simultaneous consideration of multiple time scales for the hazard of an event have been…

Methodology · Statistics 2026-03-16 Angela Carollo , Paul H. C. Eilers , Hein Putter , Jutta Gampe

Clustering is a fundamental task in network analysis, essential for uncovering hidden structures within complex systems. Edge clustering, which focuses on relationships between nodes rather than the nodes themselves, has gained increased…

Computation · Statistics 2025-07-14 Haomin Li , Daniel K. Sewell

In this study, we analyzed the problem of accelerating the linear average consensus algorithm for complex networks. We propose a data-driven approach to tuning the weights of temporal (i.e., time-varying) networks using deep learning…

Optimization and Control · Mathematics 2023-08-29 Masako Kishida , Masaki Ogura , Yuichi Yoshida , Tadashi Wadayama

The matched case-control design, up until recently mostly pertinent to epidemiological studies, is becoming customary in biomedical applications as well. For instance, in omics studies, it is quite common to compare cancer and healthy…

Methodology · Statistics 2024-02-05 Vera Djordjilović , Erica Ponzi , Therese Haugdahl Nøst , Magne Thoresen

Comparative transcriptomics has gained increasing popularity in genomic research thanks to the development of high-throughput technologies including microarray and next-generation RNA sequencing that have generated numerous transcriptomic…

Quantitative Methods · Quantitative Biology 2021-12-01 Wei Vivian Li , Yiling Chen , Jingyi Jessica Li

Signed networks, i.e., networks with positive and negative edges, commonly arise in various domains from social media to epidemiology. Modeling signed networks has many practical applications, including the creation of synthetic data sets…

Quantitative Methods · Quantitative Biology 2022-11-18 Angelina Brilliantova , Hannah Miller , Ivona Bezáková

We introduce CCMnet, an R package designed to generate network ensembles that accurately reflect the uncertainty inherent in empirical data. While traditional network modeling often results in ensembles with fixed property values or…

Computation · Statistics 2026-03-04 Ravi Goyal , Victor De Gruttola , Natasha K. Martin , Lior Rennert , Jukka-Pekka Onnela

Modeling networks can serve as a means of summarizing high-dimensional complex systems. Adapting an approach devised for dense, weighted networks, we propose a new method for generating and estimating unweighted networks. This approach can…

Physics and Society · Physics 2024-04-12 Benjamin Leinwand , Vince Lyzinski