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Tissue biopsy evaluation in the clinic is in need of quantitative disease markers for diagnosis and, most importantly, prognosis. Among the new technologies, quantitative phase imaging (QPI) has demonstrated promise for histopathology…

Current pathology workflow involves staining of thin tissue slices, which otherwise would be transparent, followed by manual investigation under the microscope by a trained pathologist. While the hematoxylin and eosin (H&E) stain is…

Medical Physics · Physics 2021-05-04 Jingfang "Kelly" Zhang , Yuchen R. He , Nahil Sobh , Gabriel Popescu

Breast cancer is one of the factors that cause the increase of mortality of women. The most widely used method for diagnosing this geological disease i.e. breast cancer is the ultrasound scan. Several key features such as the smoothness and…

Artificial Intelligence · Computer Science 2021-08-10 Mohamed Mejri , Aymen Mejri , Oumayma Mejri , Chiraz Fekih

Imaging mass spectrometry (IMS) is a powerful tool for untargeted, highly multiplexed molecular mapping of tissue in biomedical research. IMS offers a means of mapping the spatial distributions of molecular species in biological tissue with…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Yijie Zhang , Luzhe Huang , Nir Pillar , Yuzhu Li , Lukasz G. Migas , Raf Van de Plas , Jeffrey M. Spraggins , Aydogan Ozcan

Breast cancer is one of the most common and prevalent type of cancer that mainly affects the women population. chances of effective treatment increases with early diagnosis. Mammography is considered one of the effective and proven…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Bilal Ahmed Lodhi

In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-shifting interferometer, built onto a phase-contrast microscope, with white-light illumination. As one of the most sensitive quantitative phase…

Optics · Physics 2020-12-17 Xi Chen , Mikhail E. Kandel , Gabriel Popescu

Breast cancer is the most common cancer among women both in developed and developing countries. Early detection and diagnosis of breast cancer may reduce its mortality and improve the quality of life. Computer-aided detection (CADx) and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-23 Sokratis Makrogiannis , Chelsea E. Harris , Keni Zheng

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

Label-free imaging approaches seek to simplify and augment histopathologic assessment by replacing the current practice of staining by dyes to visualize tissue morphology with quantitative optical measurements. Quantitative phase imaging…

Mammograms are commonly employed in the large scale screening of breast cancer which is primarily characterized by the presence of malignant masses. However, automated image-level detection of malignancy is a challenging task given the…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Sarath Chandra K , Arunava Chakravarty , Nirmalya Ghosh , Tandra Sarkar , Ramanathan Sethuraman , Debdoot Sheet

Breast cancer is described as one of the most common types of cancer which has been diagnosed mainly in women. When compared in the ratio of male to female, it has been duly found that the prone of having breast cancer is more in females…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Poulmi Banerjee , Satadal Saha

The differentiation between pathological subtypes of non-small cell lung cancer (NSCLC) is an essential step in guiding treatment options and prognosis. However, current clinical practice relies on multi-step staining and labelling…

Quantitative Methods · Quantitative Biology 2026-03-10 Zhenya Zang , David A Dorward , Katherine E Quiohilag , Andrew DJ Wood , James R Hopgood , Ahsan R Akram , Qiang Wang

Breast cancer is the most common invasive cancer in women, and the second main cause of death. Breast cancer screening is an efficient method to detect indeterminate breast lesions early. The common approaches of screening for women are…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Yuliana Jiménez Gaona , María José Rodriguez-Alvarez , Hector Espinó Morató , Darwin Castillo Malla , Vasudevan Lakshminarayanan

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

Breast cancer is one of the most common cancers among women worldwide, with early detection significantly increasing survival rates. Ultrasound imaging is a critical diagnostic tool that aids in early detection by providing real-time…

Image and Video Processing · Electrical Eng. & Systems 2023-05-23 Mingzhe Hu , Yuheng Li , Xiaofeng Yang

Mammography is the primary imaging modality used for early detection and diagnosis of breast cancer. X-ray mammogram analysis mainly refers to the localization of suspicious regions of interest followed by segmentation, towards further…

Image and Video Processing · Electrical Eng. & Systems 2020-12-09 Yutong Yan , Pierre-Henri Conze , Gwenolé Quellec , Mathieu Lamard , Béatrice Cochener , Gouenou Coatrieux

Ultrasound image diagnosis of breast tumors has been widely used in recent years. However, there are some problems of it, for instance, poor quality, intense noise and uneven echo distribution, which has created a huge obstacle to…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Zhihao Fang , Wanyi Zhang , He Ma

Mitosis count is an important biomarker for prognosis of various cancers. At present, pathologists typically perform manual counting on a few selected regions of interest in breast whole-slide-images (WSIs) of patient biopsies. This task is…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Saad Ullah Akram , Talha Qaiser , Simon Graham , Juho Kannala , Janne Heikkilä , Nasir Rajpoot

Breast cancer is the most common invasive cancer in women. Besides the primary B-mode ultrasound screening, sonographers have explored the inclusion of Doppler, strain and shear-wave elasticity imaging to advance the diagnosis. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Wang Jian , Miao Juzheng , Yang Xin , Li Rui , Zhou Guangquan , Huang Yuhao , Lin Zehui , Xue Wufeng , Jia Xiaohong , Zhou Jianqiao , Huang Ruobing , Ni Dong

Mammography is the most effective and available tool for breast cancer screening. However, the low positive predictive value of breast biopsy resulting from mammogram interpretation leads to approximately 70% unnecessary biopsies with…

Machine Learning · Computer Science 2013-06-04 Sahar A. Mokhtar , Alaa. M. Elsayad
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