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Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

Computer Vision and Pattern Recognition · Computer Science 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

Breast cancer is the most common cancer in the world and the second most common type of cancer that causes death in women. The timely and accurate diagnosis of breast cancer using histopathological images is crucial for patient care and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Amira Alotaibi , Tarik Alafif , Faris Alkhilaiwi , Yasser Alatawi , Hassan Althobaiti , Abdulmajeed Alrefaei , Yousef M Hawsawi , Tin Nguyen

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

According to some medical imaging techniques, breast histopathology images called Hematoxylin and Eosin are considered as the gold standard for cancer diagnoses. Based on the idea of dividing the pathologic image (WSI) into multiple…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Tat-Bao-Thien Nguyen , Minh-Vuong Ngo , Van-Phong Nguyen

Breast cancer remains the most commonly diagnosed malignancy among women in the developed world. Early detection through mammography screening plays a pivotal role in reducing mortality rates. While computer-aided diagnosis (CAD) systems…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Accurate tumor segmentation and classification in breast ultrasound (BUS) imaging remain challenging due to low contrast, speckle noise, and diverse lesion morphology. This study presents a multi-task deep learning framework that jointly…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Samuel E. Johnny , Bernes L. Atabonfack , Israel Alagbe , Assane Gueye

Increased levels of tumor infiltrating lymphocytes (TILs) in cancer tissue indicate favourable outcomes in many types of cancer. Manual quantification of immune cells is inaccurate and time consuming for pathologists. Our aim is to leverage…

Mammography is widely recognized as the most reliable technique for early detection of breast cancers. Automated or semi-automated computerized classification schemes can be very useful in assisting radiologists with a second opinion about…

Medical Physics · Physics 2007-05-23 A. Retico , P. Delogu , M. E. Fantacci , P. Kasae

Breast Magnetic Resonance Imaging (MRI) demonstrates the highest sensitivity for breast cancer detection among imaging modalities and is standard practice for high-risk women. Interpreting the multi-sequence MRI is time-consuming and prone…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Luyang Luo , Mingxiang Wu , Mei Li , Yi Xin , Qiong Wang , Varut Vardhanabhuti , Winnie CW Chu , Zhenhui Li , Juan Zhou , Pranav Rajpurkar , Hao Chen

The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

Breast cancer prediction models for mammography assume that annotations are available for individual images or regions of interest (ROIs), and that there is a fixed number of images per patient. These assumptions do not hold in real…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Shreyasi Pathak , Jörg Schlötterer , Jeroen Geerdink , Jeroen Veltman , Maurice van Keulen , Nicola Strisciuglio , Christin Seifert

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

Label-free chemical imaging holds significant promise for improving digital pathology workflows, but data acquisition speed remains a limiting factor. To address this gap, we propose an adaptive strategy-initially scan the low information…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Ji-Hun Oh , Kianoush Falahkheirkhah , Rohit Bhargava

Lymph node metastasis is one of the most significant diagnostic indicators in breast cancer, which is traditionally observed under the microscope by pathologists. In recent years, computerized histology diagnosis has become one of the most…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Huangjing Lin , Hao Chen , Qi Dou , Liansheng Wang , Jing Qin , Pheng-Ann Heng

Patch-wise multi-label classification provides an efficient alternative to full pixel-wise segmentation on high-resolution images, particularly when the objective is to determine the presence or absence of target objects within a patch…

Machine Learning · Computer Science 2025-11-18 Ihab Asaad , Maha Shadaydeh , Joachim Denzler

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Automatic diagnosis of malignant melanoma highly depends on the segmentation methods used for the suspicious lesion. We suggest the parameter selection method (PSM) and maximum area method (MAM) for the segmentation of the lesion to be…

Image and Video Processing · Electrical Eng. & Systems 2020-05-05 Seungmin Park , Hyunju Lee , Kiwoon Kwon

Mammography screening for early detection of breast lesions currently suffers from high amounts of false positive findings, which result in unnecessary invasive biopsies. Diffusion-weighted MR images (DWI) can help to reduce many of these…

The improved diagnostic accuracy of ultrasound breast examinations remains an important goal. In this study, we propose a biophysical feature based machine learning method for breast cancer detection to improve the performance beyond a…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Jihye Baek , Avice M. O'Connell , Kevin J. Parker

Breast cancer has the highest incidence and second highest mortality rate for women in the US. Our study aims to utilize deep learning for benign/malignant classification of mammogram tumors using a subset of cases from the Digital Database…

Computer Vision and Pattern Recognition · Computer Science 2017-05-19 Darvin Yi , Rebecca Lynn Sawyer , David Cohn , Jared Dunnmon , Carson Lam , Xuerong Xiao , Daniel Rubin