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In a mathematical model of interacting biological organisms, where external interventions may alter behavior over time, traditional models that assume fixed parameters usually do not capture the evolving dynamics. In oncology, this is…

Machine Learning · Computer Science 2025-12-18 Kayode Olumoyin , Lamees El Naqa , Katarzyna Rejniak

A biological regulatory network can be modeled as a discrete function that contains all available information on network component interactions. From this function we can derive a graph representation of the network structure as well as of…

Discrete Mathematics · Computer Science 2009-10-09 Heike Siebert

In the big data era, the relationship between entries becomes more and more complex. Many graph (or network) algorithms have already paid attention to dynamic networks, which are more suitable than static ones for fitting the complex…

Machine Learning · Computer Science 2022-11-17 Dongqi Fu , Jingrui He

Emerging technologies like hypersonic aircraft, space exploration vehicles, and batteries avail fluid circulation in embedded microvasculatures for efficient thermal regulation. Modeling is vital during these engineered systems' design and…

Numerical Analysis · Mathematics 2023-05-16 N. V. Jagtap , M. K. Mudunuru , K. B. Nakshatrala

Accurate forecasting of viral disease outbreaks is crucial for guiding public health responses and preventing widespread loss of life. In recent years, Physics-Informed Neural Networks (PINNs) have emerged as a promising framework that can…

Quantitative Methods · Quantitative Biology 2025-08-12 Bikram Das , Rupchand Sutradhar , D C Dalal

Physics-informed machine learning (PIML) is emerging as a potentially transformative paradigm for modeling complex biomedical systems by integrating parameterized physical laws with data-driven methods. Here, we review three main classes of…

Machine Learning · Computer Science 2025-10-08 Nazanin Ahmadi , Qianying Cao , Jay D. Humphrey , George Em Karniadakis

Systems biology and systems neurophysiology in particular have recently emerged as powerful tools for a number of key applications in the biomedical sciences. Nevertheless, such models are often based on complex combinations of multiscale…

Neural and Evolutionary Computing · Computer Science 2022-09-27 Matteo Ferrante , Andera Duggento , Nicola Toschi

The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the interpretation of clinical data. However, high-resolution and…

Considering the growing necessity for precise modeling of power electronics amidst operational and environmental uncertainties, this paper introduces an innovative methodology that ingeniously combines model-driven and data-driven…

Systems and Control · Electrical Eng. & Systems 2024-06-25 Peifeng Hui , Chenggang Cui , Pengfeng Lin , Amer M. Y. M. Ghias , Xitong Niu , Chuanlin Zhang

This paper introduces a novel approach to solve inverse problems by leveraging deep learning techniques. The objective is to infer unknown parameters that govern a physical system based on observed data. We focus on scenarios where the…

Machine Learning · Computer Science 2023-10-02 Sidney Besnard , Frédéric Jurie , Jalal M. Fadili

Click-through rate prediction is an essential task in industrial applications, such as online advertising. Recently deep learning based models have been proposed, which follow a similar Embedding\&MLP paradigm. In these methods large scale…

Machine Learning · Statistics 2018-09-14 Guorui Zhou , Chengru Song , Xiaoqiang Zhu , Ying Fan , Han Zhu , Xiao Ma , Yanghui Yan , Junqi Jin , Han Li , Kun Gai

Varying power-infeed from converter-based generation units introduces great uncertainty on system parameters such as inertia and damping. As a consequence, system operators face increasing challenges in performing dynamic security…

Systems and Control · Electrical Eng. & Systems 2021-04-16 Jochen Stiasny , George S. Misyris , Spyros Chatzivasileiadis

Opinion formation and propagation are crucial phenomena in social networks and have been extensively studied across several disciplines. Traditionally, theoretical models of opinion dynamics have been proposed to describe the interactions…

Social and Information Networks · Computer Science 2022-07-11 Maya Okawa , Tomoharu Iwata

Traditional neural networks, while powerful, rely on biologically implausible learning mechanisms such as global backpropagation. This paper introduces the Structurally Adaptive Predictive Inference Network (SAPIN), a novel computational…

Neural and Evolutionary Computing · Computer Science 2026-02-11 Brennen A. Hill

A dynamic logic method was developed to analyze molecular networks of cells by combining Kauffman and Thomas's logic operations with molecular interaction parameters. The logic operations characterize the discrete interactions between…

Quantitative Methods · Quantitative Biology 2008-06-11 Suping Lyu

Dynamic models of signaling networks allow the formulation of hypotheses on the topology and kinetic rate laws characterizing a given molecular network, in-depth exploration and confrontation with kinetic biological data. Despite its…

Molecular Networks · Quantitative Biology 2018-08-01 Romain Yvinec , Mohammed Akli Ayoub , Francesco De Pascali , Pascale Crépieux , Eric Reiter , Anne Poupon

We develop improved physics-informed neural networks (PINNs) for high-order and high-dimensional power system models described by nonlinear ordinary differential equations. We propose some novel enhancements to improve PINN training and…

Machine Learning · Computer Science 2024-10-11 Vineet Jagadeesan Nair

Identifying accurate dynamic models is required for the simulation and control of various technical systems. In many important real-world applications, however, the two main modeling approaches often fail to meet requirements: first…

Machine Learning · Computer Science 2021-04-19 Manuel A. Roehrl , Thomas A. Runkler , Veronika Brandtstetter , Michel Tokic , Stefan Obermayer

In personalized recommendation systems, accurately capturing users' evolving interests and combining them with contextual information is a critical research area. This paper proposes a novel model called the Deep Adaptive Interest Network…

Information Retrieval · Computer Science 2024-12-25 Shuaishuai Huang , Haowei Yang , You Yao , Xueting Lin , Yuming Tu

Network science has become an essential interdisciplinary tool for understanding complex biological systems. However, because these systems undergo continuous, often stimulus-driven changes in both structure and function, traditional static…

Molecular Networks · Quantitative Biology 2025-05-19 Abir Khazaal , Fatemeh Vafaee