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The assumption of hazard rates being proportional in covariates is widely made in empirical research and extensive research has been done to develop tests of its validity. This paper does not contribute on this end. Instead, it gives new…

Methodology · Statistics 2025-08-15 Simon M. S. Lo , Ralf A. Wilke , Takeshi Emura

In this paper, we consider multivariate response regression models with high dimensional predictor variables. One way to model the correlation among the response variables is through the low rank decomposition of the coefficient matrix,…

Methodology · Statistics 2015-08-06 Ruiyan Luo , Xin Qi

This paper investigates the high-dimensional linear regression with highly correlated covariates. In this setup, the traditional sparsity assumption on the regression coefficients often fails to hold, and consequently many model selection…

Methodology · Statistics 2019-03-26 Jianqing Fan , Bai Jiang , Qiang Sun

Causal inference is known to be very challenging when only observational data are available. Randomized experiments are often costly and impractical and in instrumental variable regression the number of instruments has to exceed the number…

Methodology · Statistics 2018-06-19 Dominik Rothenhäusler , Peter Bühlmann , Nicolai Meinshausen

The Cox proportional hazards model is a canonical method in survival analysis for prediction of the life expectancy of a patient given clinical or genetic covariates -- it is a linear model in its original form. In recent years, several…

Machine Learning · Statistics 2022-08-23 Xuelin Yang , Louis Abraham , Sejin Kim , Petr Smirnov , Feng Ruan , Benjamin Haibe-Kains , Robert Tibshirani

We study a regression model with a huge number of interacting variables. We consider a specific approximation of the regression function under two ssumptions: (i) there exists a sparse representation of the regression function in a…

Statistics Theory · Mathematics 2009-09-29 Peter J. Bickel , Ya'acov Ritov , Alexander B. Tsybakov

This paper studies a Dantzig-selector type regularized estimator for linear functionals of high-dimensional linear processes. Explicit rates of convergence of the proposed estimator are obtained and they cover the broad regime from i.i.d.…

Statistics Theory · Mathematics 2016-11-23 Xiaohui Chen , Mengyu Xu , Wei Biao Wu

We propose a computationally and statistically efficient divide-and-conquer (DAC) algorithm to fit sparse Cox regression to massive datasets where the sample size $n_0$ is exceedingly large and the covariate dimension $p$ is not small but…

Computation · Statistics 2018-04-04 Yan Wang , Nathan Palmer , Qian Di , Joel Schwartz , Isaac Kohane , Tianxi Cai

This paper develops an approach to inference in a linear regression model when the number of potential explanatory variables is larger than the sample size. The approach treats each regression coefficient in turn as the interest parameter,…

Methodology · Statistics 2022-11-14 Heather S. Battey , Nancy Reid

High-dimensional sparse modeling via regularization provides a powerful tool for analyzing large-scale data sets and obtaining meaningful, interpretable models. The use of nonconvex penalty functions shows advantage in selecting important…

Methodology · Statistics 2016-05-12 Zemin Zheng , Yingying Fan , Jinchi Lv

This paper studies a tensor-structured linear regression model with a scalar response variable and tensor-structured predictors, such that the regression parameters form a tensor of order $d$ (i.e., a $d$-fold multiway array) in…

Machine Learning · Computer Science 2020-11-26 Talal Ahmed , Haroon Raja , Waheed U. Bajwa

This paper studies nonparametric series estimation and inference for the effect of a single variable of interest x on an outcome y in the presence of potentially high-dimensional conditioning variables z. The context is an additively…

Statistics Theory · Mathematics 2020-04-07 Damian Kozbur

Standard penalized methods of variable selection and parameter estimation rely on the magnitude of coefficient estimates to decide which variables to include in the final model. However, coefficient estimates are unreliable when the design…

Methodology · Statistics 2018-02-13 Jonathan P Williams , Jan Hannig

We present biniLasso and its sparse variant (sparse biniLasso), novel methods for prognostic analysis of high-dimensional survival data that enable detection of multiple cut-points per feature. Our approach leverages the Cox proportional…

Methodology · Statistics 2026-02-13 Abdollah Safari , Hamed Halisaz , Peter Loewen

Penalized (or regularized) regression, as represented by Lasso and its variants, has become a standard technique for analyzing high-dimensional data when the number of variables substantially exceeds the sample size. The performance of…

Methodology · Statistics 2019-08-13 Yunan Wu , Lan Wang

Survival analysis often relies on Cox models, assuming both linearity and proportional hazards (PH). This study evaluates machine and deep learning methods that relax these constraints, comparing their performance with penalized Cox models…

Machine Learning · Computer Science 2025-10-21 Ivan Rossi , Flavio Sartori , Cesare Rollo , Giovanni Birolo , Piero Fariselli , Tiziana Sanavia

We consider a flexible semiparametric quantile regression model for analyzing high dimensional heterogeneous data. This model has several appealing features: (1) By considering different conditional quantiles, we may obtain a more complete…

Statistics Theory · Mathematics 2016-01-25 Ben Sherwood , Lan Wang

In the analysis of survival outcome supplemented with both clinical information and high-dimensional gene expression data, use of the traditional Cox proportional hazards model (1972) fails to meet some emerging needs in biomedical…

Computation · Statistics 2018-02-26 Jean Claude Utazirubanda , Tomas Leon , Papa Ngom

The Cox proportional hazards model, commonly used in clinical trials, assumes proportional hazards. However, it does not hold when, for example, there is a delayed onset of the treatment effect. In such a situation, an acute change in the…

Methodology · Statistics 2022-04-22 Ryoto Ozaki , Yoshiyuki Ninomiya

We study large sample properties of Bayesian analysis of the proportional hazard model with neutral to the right process priors on the baseline hazard function. We show that the posterior distribution of the baseline cumulative hazard…

Statistics Theory · Mathematics 2007-06-13 Yongdai Kim