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Peripheral membrane proteins can reversibly and specifically bind to biological membranes to carry out functions such as cell signalling, enzymatic activity, or membrane remodelling. Structures of these proteins and of their lipid-binding…

Biological Physics · Physics 2023-11-14 Andreas Haahr Larsen , Laura H. John , Mark S. P. Sansom , Robin A. Corey

Spherical symmetry is ubiquitous in nature. It's therefore unfortunate that spherical system simulations are so hard, and require complete spheres with millions of interacting particles. Here we introduce an approach to model spherical…

Materials Science · Physics 2011-10-07 Pekka Koskinen , Oleg O. Kit

In this review we discuss the recent progress in the simulation of soft active matter systems and in particular the hydrodynamics of microswimmers using the method of multiparticle collision dynamics, which solves the hydrodynamic flows…

Soft Condensed Matter · Physics 2020-09-03 Andreas Zöttl

Coarse-grained continuous descriptions for lipid bilayers are typically based on minimizing the Helfrich energy. Such models consider the fluid properties of these structures only implicitly and have been shown to nicely reproduce…

Soft Condensed Matter · Physics 2026-04-29 Ingo Nitschke , Jan Magnus Sischka , Axel Voigt

Lipid bilayer membranes have a native (albeit small) permeability for water molecules. Under an external load, provided that the bilayer structure stays intact and does not suffer from poration or rupture, a lipid membrane deforms and its…

Soft Condensed Matter · Physics 2021-07-14 Bryan Quaife , Ashley Gannon , Y. -N. Young

We study, using dissipative particle dynamics simulations, the effect of active lipid flip-flop on model fluid bilayer membranes. We consider both cases of symmetric as well as asymmetric flip-flops. Symmetric flip-flop leads to a steady…

Soft Condensed Matter · Physics 2009-11-13 Sanoop Ramachandran , P. B. Sunil Kumar , Mohamed Laradji

Simulating protein-membrane interactions is an important and dynamic area of research. A proper definition of electrostatic forces on membrane surfaces is necessary for developing electromechanical models of protein-membrane interactions.…

Analysis of PDEs · Mathematics 2013-09-24 Michael Mikucki , Y. C. Zhou

Gaining access to the cell interior is fundamental for many applications, such as electrical recording, drug and biomolecular delivery. A very promising technique consists of culturing cells on nano/micro pillars. The tight adhesion and…

Simple models for spherical particles with a soft shell have been shown to self-assemble into numerous crystal phases and even quasicrystals. However, most of these models rely on a simple pairwise interaction, which is usually a valid…

Soft Condensed Matter · Physics 2020-09-03 Emanuele Boattini , Nina Bezem , Sudeep N. Punnathanam , Frank Smallenburg , Laura Filion

Measurements with an atomic force microscope (AFM) offer a direct way to probe elastic properties of lipid bilayer membranes locally: provided the underlying stress-strain relation is known, material parameters such as surface tension or…

Soft Condensed Matter · Physics 2007-05-23 Davood Norouzi , Martin Michael Mueller , Markus Deserno

We have constructed a model for the kinetics of rupture of membranes under tension, applying physical principles relevant to lipid bilayers held together by hydrophobic interactions. The membrane is characterized by the bulk compressibility…

Biological Physics · Physics 2009-11-07 Luc Fournier , Bela Joos

We construct a coarse-grained (CG) model for dipalmitoylphosphatidylcholine (DPPC)/cholesterol bilayers and apply it to large-scale simulation studies of lipid membranes. Our CG model is a two-dimensional representation of the membrane,…

Soft Condensed Matter · Physics 2009-11-10 Teemu Murtola , Emma Falck , Michael Patra , Mikko Karttunen , Ilpo Vattulainen

A surrogate model for particle-in-cell plasma simulations based on a graph neural network is presented. The graph is constructed in such a way as to enable the representation of electromagnetic fields on a fixed spatial grid. The model is…

Plasma Physics · Physics 2025-03-04 Marin Mlinarević , George K. Holt , Adriano Agnello

We consider a model of bilayer lipid membrane with bola-lipids. The bola-lipid is modeled by linking tails of the hydrophobic chains in the opposite monolayers within bilayer as a first approximation. A number of thermodynamical…

Biomolecules · Quantitative Biology 2016-02-26 Sergei I. Mukhin , Boris B. Kheyfets

We use molecular dynamics simulations to study the evaporation of particle-laden droplets on a heated surface. The droplets are composed of a Lennard-Jones fluid containing rigid particles which are spherical sections of an atomic lattice,…

Soft Condensed Matter · Physics 2015-06-04 Weikang Chen , Joel Koplik , Ilona Kretzschmar

We study the linearized hydrodynamics of a two-component fluid membrane near a repulsive wall, via a model which incorporates curvature- concentration coupling as well as hydrodynamic interactions. This model is a simplified version of a…

Soft Condensed Matter · Physics 2009-11-07 Sumithra Sankararaman , Gautam I. Menon , P. B. Sunil Kumar

We consider the lateral diffusion of a protein interacting with the curvature of the membrane. The interaction energy is minimized if the particle is at a membrane position with a certain curvature that agrees with the spontaneous curvature…

Soft Condensed Matter · Physics 2008-12-10 Stefan M. Leitenberger , Ellen Reister-Gottfried , Udo Seifert

Certain sequences of peptoid polymers (synthetic analogs of peptides) assemble into bilayer nanosheets via a nonequilibrium assembly pathway of adsorption, compression, and collapse at an air-water interface. As with other large-scale…

Biological Physics · Physics 2014-10-01 Thomas K. Haxton , Ranjan V. Mannige , Ronald N. Zuckermann , Stephen Whitelam

Heterogeneities in the cell membrane due to coexisting lipid phases have been conjectured to play a major functional role in cell signaling and membrane trafficking. Thereby the material properties of multiphase systems, such as the line…

Soft Condensed Matter · Physics 2013-04-17 Stefan Semrau , Timon Idema , Laurent Holtzer , Thomas Schmidt , Cornelis Storm

First, a meshless simulation method is presented for multiphase fluid-particle flows with a two-way coupled Smoothed Particle Hydrodynamics (SPH) for the fluid and the Discrete Element Method (DEM) for the solid phase. The unresolved fluid…

Fluid Dynamics · Physics 2014-02-28 Martin Robinson , Stefan Luding , Marco Ramaioli
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