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Kidney transplantation is the preferred treatment for people suffering from end-stage renal disease. Successful kidney transplants still fail over time, known as graft failure; however, the time to graft failure, or graft survival time, can…

Machine Learning · Computer Science 2022-11-07 Zhipeng Huang , Kevin S. Xu

The kidney exchange problem (KEP) seeks to find possible exchanges among pairs of patients and their incompatible kidney donors while meeting specific optimization criteria such as maximizing the overall number of possible transplants.…

Cryptography and Security · Computer Science 2024-02-02 Malte Breuer , Ulrike Meyer , Susanne Wetzel

Organ transplants can improve the life expectancy and quality of life for the recipient but carries the risk of serious post-operative complications, such as septic shock and organ rejection. The probability of a successful transplant…

Machine Learning · Computer Science 2016-11-15 Jinsung Yoon , Ahmed M. Alaa , Martin Cadeiras , Mihaela van der Schaar

Renal patients which have a willing but incompatible donor can decide to participate in a kidney exchange program (KEP). The goal of a KEP is to identify sets of such incompatible pairs that can exchange donors, leading to compatible…

Optimization and Control · Mathematics 2023-02-24 Danny Blom , Christopher Hojny , Bart Smeulders

We study dynamic matching in exchange markets with easy- and hard-to-match agents. A greedy policy, which attempts to match agents upon arrival, ignores the positive externality that waiting agents generate by facilitating future matchings.…

Theoretical Economics · Economics 2019-06-14 Itai Ashlagi , Afshin Nikzad , Philipp Strack

Heart transplantation is a viable path for patients suffering from advanced heart failure, but this lifesaving option is severely limited due to donor shortage. Although the current allocation policy was recently revised in 2018, a major…

Machine Learning · Computer Science 2025-12-16 Ioannis Anagnostides , Zachary W. Sollie , Arman Kilic , Tuomas Sandholm

Kidney paired donation programs allow patients registered with an incompatible donor to receive a suitable kidney from another donor, as long as the latter's co-registered patient, if any, also receives a kidney from a different donor. The…

Optimization and Control · Mathematics 2023-03-13 Lizeth Carolina Riascos-Álvarez , Merve Bodur , Dionne M. Aleman

Given AI's growing role in modeling and improving decision-making, how and when to present users with feedback is an urgent topic to address. We empirically examined the effect of feedback from false AI on moral decision-making about donor…

In Kidney Exchange Programs (KEPs), each participating patient is registered together with an incompatible donor. Donors without an incompatible patient can also register. Then, KEPs typically maximize overall patient benefit through donor…

Optimization and Control · Mathematics 2025-03-04 William St-Arnaud , Margarida Carvalho , Golnoosh Farnadi

Incompatibility between patient and donor is a major barrier in kidney transplantation (KT). The increasing shortage of kidney donors has driven the development of desensitization techniques to overcome this immunological challenge.…

Systems and Control · Electrical Eng. & Systems 2025-04-29 Xingyu Ren , Michael C. Fu , Steven I. Marcus

Kidney transplantation is the best treatment for end-stage renal failure patients. The predominant method used for kidney quality assessment is the Cox regression-based, kidney donor risk index. A machine learning method may provide…

Machine Learning · Computer Science 2020-12-08 Eric S. Pahl , W. Nick Street , Hans J. Johnson , Alan I. Reed

A growing body of work in Ethical AI attempts to capture human moral judgments through simple computational models. The key question we address in this work is whether such simple AI models capture {the critical} nuances of moral…

Human-Computer Interaction · Computer Science 2025-03-04 Vijay Keswani , Vincent Conitzer , Walter Sinnott-Armstrong , Breanna K. Nguyen , Hoda Heidari , Jana Schaich Borg

To overcome incompatibility issues, kidney patients may swap their donors. In international kidney exchange programmes (IKEPs), countries merge their national patient-donor pools. We consider a recently introduced credit system. In each…

Computer Science and Game Theory · Computer Science 2023-02-24 Márton Benedek , Péter Biró , Daniël Paulusma , Xin Ye

Balancing fairness and efficiency in resource allocation is a classical economic and computational problem. The price of fairness measures the worst-case loss of economic efficiency when using an inefficient but fair allocation rule; for…

Computer Science and Game Theory · Computer Science 2017-09-11 Duncan C. McElfresh , John P. Dickerson

Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another…

Machine Learning · Computer Science 2022-07-07 Mohammadreza Nemati , Haonan Zhang , Michael Sloma , Dulat Bekbolsynov , Hong Wang , Stanislaw Stepkowski , Kevin S. Xu

We study the allocation of deceased-donor lungs to patients in need of a transplant. Patients make sequential decisions in an order dictated by a priority policy. Using data from a prominent Organ Procurement Organization in the United…

General Economics · Economics 2024-11-19 Laura Doval , Federico Echenique Wanying Huang , Yi Xin

This paper addresses the problem of maximizing the expected size of a matching in the case of unreliable vertices and/or edges. The assumption is that upon failure, remaining vertices that have not been matched may be subject to a new…

Data Structures and Algorithms · Computer Science 2016-05-30 João Pedro Pedroso , Shiro Ikeda

We study the problem of dynamic matching in heterogeneous networks, where agents are subject to compatibility restrictions and stochastic arrival and departure times. In particular, we consider networks with one type of easy-to-match agents…

Machine Learning · Computer Science 2023-03-09 Xiaowu Dai , Hengzhi He

In this paper I explore the human organ procurement system. Which is better for saving lives and limiting black market use, the present altruistic system of donations or a free and open sales market? I explain that there is a risk with…

Other Quantitative Biology · Quantitative Biology 2015-01-14 Michael Hentrich

To this day, there are still some countries where the exchange of kidneys between multiple incompatible patient-donor pairs is restricted by law. Typically, legal regulations in this context are put in place to prohibit coercion and…

Cryptography and Security · Computer Science 2022-06-03 Malte Breuer , Ulrike Meyer , Susanne Wetzel