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We design a flexible algorithm that exploits deceased donor kidneys to initiate chains of living donor kidney paired donations, combining deceased and living donor allocation mechanisms to improve the quantity and quality of kidney…

Tissues and Organs · Quantitative Biology 2019-01-09 Cristina Cornelio , Lucrezia Furian , Antonio Nicolo' , Francesca Rossi

Kidney exchange programs have been developed to find compatible kidneys for recipients who have incompatible donors. On the other hand, patients who do not have a living donor depend upon deceased donor (DD) donations to get a kidney…

Optimization and Control · Mathematics 2020-10-13 Utkarsh Verma , Narayan Rangaraj

The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the…

Computers and Society · Computer Science 2019-08-22 Ehsan Khan , Avishek Choudhury , Amy L Friedman , Daehan Won

Kidney transplants are sharply overdemanded in the United States. A recent innovation to address organ shortages is a kidney exchange, in which willing but medically incompatible patient-donor pairs swap donors so that two successful…

Computer Science and Game Theory · Computer Science 2019-12-24 Irena Gao

Kidney donations from living donors form an attractive alternative to long waiting times on a list for a post-mortem donation. However, even if a living donor for a given patient is found, the donor's kidney might not meet the patient's…

Cryptography and Security · Computer Science 2020-11-11 Malte Breuer , Ulrike Meyer , Susanne Wetzel , Anja Mühlfeld

Kidney transplantation is the preferred treatment for end-stage renal disease, yet the scarcity of donors and inefficiencies in allocation systems create major bottlenecks, resulting in prolonged wait times and alarming mortality rates.…

Computer Science and Game Theory · Computer Science 2024-10-15 Sean Berry , Berk Gorgulu , Sait Tunc , Mucahit Cevik , Matthew J Ellis

We consider a well-studied online random graph model for kidney exchange, where nodes representing patient-donor pairs arrive over time, and the probability of a directed edge is p. We assume existence of a single altruistic donor, who…

Computer Science and Game Theory · Computer Science 2020-10-06 Avrim Blum , Yishay Mansour

A kidney exchange program, also called a kidney paired donation program, can be viewed as a repeated, dynamic trading and allocation mechanism. This suggests that a dynamic algorithm for transplant exchange selection may have superior…

Optimization and Control · Mathematics 2023-09-26 Margarida Carvalho , Alison Caulfield , Yi Lin , Adrian Vetta

The kidney paired donation (KPD) program provides an innovative solution to overcome incompatibility challenges in kidney transplants by matching incompatible donor-patient pairs and facilitating kidney exchanges. To address unequal access…

Methodology · Statistics 2026-01-21 Mingrui Zhang , Xiaowu Dai , Lexin Li

A kidney exchange is a centrally-administered barter market where patients swap their willing yet incompatible donors. Modern kidney exchanges use 2-cycles, 3-cycles, and chains initiated by non-directed donors (altruists who are willing to…

Computer Science and Game Theory · Computer Science 2017-05-29 Gabriele Farina , John P. Dickerson , Tuomas Sandholm

AI algorithms increasingly make decisions that impact entire groups of humans. Since humans tend to hold varying and even conflicting preferences, AI algorithms responsible for making decisions on behalf of such groups encounter the problem…

Artificial Intelligence · Computer Science 2020-06-18 Rachel Freedman

Algorithms for exchange of kidneys is one of the key successful applications in market design, artificial intelligence, and operations research. Potent immunosuppressant drugs suppress the body's ability to reject a transplanted organ up to…

Computer Science and Game Theory · Computer Science 2021-03-04 Haris Aziz , Agnes Cseh , John P. Dickerson , Duncan C. McElfresh

The efficient and fair allocation of limited resources is a classical problem in economics and computer science. In kidney exchanges, a central market maker allocates living kidney donors to patients in need of an organ. Patients and donors…

Artificial Intelligence · Computer Science 2020-05-21 Rachel Freedman , Jana Schaich Borg , Walter Sinnott-Armstrong , John P. Dickerson , Vincent Conitzer

In barter exchanges, participants swap goods with one another without exchanging money; exchanges are often facilitated by a central clearinghouse, with the goal of maximizing the aggregate quality (or number) of swaps. Barter exchanges are…

Artificial Intelligence · Computer Science 2020-10-26 Duncan C McElfresh , Michael Curry , Tuomas Sandholm , John P Dickerson

In this paper, I summarize our work on online fair division. In particular, I present two models for online fair division: (1) one existing model for fair division in food banks and (2) one new model for fair division of deceased organs to…

Computer Science and Game Theory · Computer Science 2017-02-21 Martin Aleksandrov

Motivated by kidney exchange, we study the following mechanism-design problem: On a directed graph (of transplant compatibilities among patient-donor pairs), the mechanism must select a simple path (a chain of transplantations) starting at…

Computer Science and Game Theory · Computer Science 2021-06-23 Avrim Blum , Paul Gölz

We propose a simulation-optimization-based methodology to improve the way that organ transplant offers are made to potential recipients. Our policy can be applied to all types of organs, is implemented starting at the local level, is…

Medical Physics · Physics 2022-12-01 Ignacio Erazo , David Goldsman , Pinar Keskinocak , Joel Sokol

A kidney exchange is an organized barter market where patients in need of a kidney swap willing but incompatible donors. Determining an optimal set of exchanges is theoretically and empirically hard. Traditionally, exchanges took place in…

Data Structures and Algorithms · Computer Science 2016-06-14 John P. Dickerson , David F. Manlove , Benjamin Plaut , Tuomas Sandholm , James Trimble

Relatives and friends of an end-stage renal disease patient who offer to donate a kidney are often found to be incompatible with their intended recipients. Kidney paired donation matches one patient and his incompatible donor with another…

Computer Science and Game Theory · Computer Science 2017-10-24 Sommer Gentry , Michal Mankowski , T. S. Michael , Dorry Segev

The Kidney Exchange Problem is a prominent challenge in healthcare and economics, arising in the context of organ transplantation. It has been extensively studied in artificial intelligence and optimization. In a kidney exchange, a set of…

Data Structures and Algorithms · Computer Science 2026-05-12 Kangyi Tian , Mingyu Xiao
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