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Cellular electron cryo-tomography enables the 3D visualization of cellular organization in the near-native state and at submolecular resolution. However, the contents of cellular tomograms are often complex, making it difficult to…

Quantitative Methods · Quantitative Biology 2017-12-29 Xiangrui Zeng , Miguel Ricardo Leung , Tzviya Zeev-Ben-Mordehai , Min Xu

Quantum autoencoder is an efficient variational quantum algorithm for quantum data compression. However, previous quantum autoencoders fail to compress and recover high-rank mixed states. In this work, we discuss the fundamental properties…

Quantum Physics · Physics 2021-05-07 Chenfeng Cao , Xin Wang

The transition to 100% renewable energy requires new techniques for managing energy networks, such as dividing them into sensible subsets of prosumers called micro-grids. Doing so in an optimal manner is a difficult optimization problem, as…

Dynamic quantum simulation is a leading application for achieving quantum advantage. However, high circuit depths remain a limiting factor on near-term quantum hardware. We present a compilation algorithm based on Matrix Product Operators…

Quantum Physics · Physics 2025-07-16 Joe Gibbs , Lukasz Cincio

Quantum dynamics compilation is an important task for improving quantum simulation efficiency: It aims to synthesize multi-qubit target dynamics into a circuit consisting of as few elementary gates as possible. Compared to deterministic…

Quantum Physics · Physics 2024-09-26 Yuxuan Zhang , Roeland Wiersema , Juan Carrasquilla , Lukasz Cincio , Yong Baek Kim

Quantum machine learning aims to release the prowess of quantum computing to improve machine learning methods. By combining quantum computing methods with classical neural network techniques we aim to foster an increase of performance in…

High Energy Physics - Phenomenology · Physics 2021-03-17 Andrew Blance , Michael Spannowsky

Quantum computing has recently emerged as a transformative technology. Yet, its promised advantages rely on efficiently translating quantum operations into viable physical realizations. In this work, we use generative machine learning…

Quantum Physics · Physics 2024-05-22 Florian Fürrutter , Gorka Muñoz-Gil , Hans J. Briegel

Tiered latent representations and latent spaces for molecular graphs provide a simple but effective way to explicitly represent and utilize groups (e.g., functional groups), which consist of the atom (node) tier, the group tier and the…

Machine Learning · Computer Science 2019-08-26 Daniel T. Chang

Quantum computing requires the optimization of control pulses to achieve high-fidelity quantum gates. We propose a machine learning-based protocol to address the challenges of evaluating gradients and modeling complex system dynamics. By…

Quantum Physics · Physics 2026-01-27 Paul Surrey , Julian D. Teske , Tobias Hangleiter , Hendrik Bluhm , Pascal Cerfontaine

Considering recent advancements and successes in the development of efficient quantum algorithms for electronic structure calculations --- alongside impressive results using machine learning techniques for computation --- hybridizing…

Quantum Physics · Physics 2018-10-24 Rongxin Xia , Sabre Kais

Accurate prediction of protein active-site structures remains a central challenge in structural biology, particularly for short and flexible peptide fragments where conventional and simulation-based methods often fail. Here, we present a…

Prediction of a molecule's 3D conformer ensemble from the molecular graph holds a key role in areas of cheminformatics and drug discovery. Existing generative models have several drawbacks including lack of modeling important molecular…

In order to efficiently explore the chemical space of all possible small molecules, a common approach is to compress the dimension of the system to facilitate downstream machine learning tasks. Towards this end, we present a data driven…

Biomolecules · Quantitative Biology 2024-01-23 Paula Mercurio , Di Liu

We present a comprehensive investigation into the learning capabilities of a simple d-level system (qudit). Our study is specialized for classification tasks using real-world databases, specifically the Iris, breast cancer, and MNIST…

Quantum Physics · Physics 2025-03-26 Sebastián Roca-Jerat , Juan Román-Roche , David Zueco

Transformers have become methods of choice in many applications thanks to their ability to represent complex interactions between elements. However, extending the Transformer architecture to non-sequential data such as molecules and…

Machine Learning · Computer Science 2022-04-27 Yoni Choukroun , Lior Wolf

Autoencoders are neural network formulations where the input and output of the network are identical and the goal is to identify the hidden representation in the provided datasets. Generally, autoencoders project the data nonlinearly onto a…

Signal Processing · Electrical Eng. & Systems 2019-07-10 Debjani Bhowick , Deepak K. Gupta , Saumen Maiti , Uma Shankar

We show how techniques from machine learning and optimization can be used to find circuits of photonic quantum computers that perform a desired transformation between input and output states. In the simplest case of a single input state,…

A key challenge for molecular dynamics simulations is efficient exploration of free energy landscapes over relevant collective variables (CV). Common methods for enhancing sampling become prohibitively inefficient beyond only a few CVs; in…

Chemical Physics · Physics 2026-05-29 Nils E. Strand , Siyao Yang , Yuehaw Khoo , Aaron R. Dinner

Quantum machine learning (QML) has great potential for the analysis of chemical datasets. However, conventional quantum data-encoding schemes, such as fingerprint encoding, are generally unfeasible for the accurate representation of…

Quantum Physics · Physics 2025-11-18 Choy Boy , Edoardo Altamura , Dilhan Manawadu , Ivano Tavernelli , Stefano Mensa , David J. Wales

We present a novel algorithm to reduce tensor compute required by a conditional image generation autoencoder without sacrificing quality of photo-realistic image generation. Our method is device agnostic, and can optimize an autoencoder for…

Computer Vision and Pattern Recognition · Computer Science 2022-10-17 Nisarg A. Shah , Gaurav Bharaj