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We present a dynamic learning paradigm for "programming" a general quantum computer. A learning algorithm is used to find the control parameters for a coupled qubit system, such that the system at an initial time evolves to a state in which…

Quantum Physics · Physics 2008-08-12 E. C. Behrman , J. E. Steck , P. Kumar , K. A. Walsh

Binding energy is a fundamental thermodynamic property that governs molecular interactions, playing a crucial role in fields such as healthcare and the natural sciences. It is particularly relevant in drug development, vaccine design, and…

Quantum Physics · Physics 2025-08-06 Erico Souza Teixeira , Lucas Barros Fernandes , Yara Rodrigues Inácio

In this paper, we investigate neural networks applied to multiscale simulations and discuss a design of a novel deep neural network model reduction approach for multiscale problems. Due to the multiscale nature of the medium, the fine-grid…

Numerical Analysis · Mathematics 2024-12-20 Min Wang , Siu Wun Cheung , Wing Tat Leung , Eric T. Chung , Yalchin Efendiev , Mary Wheeler

Numerous molecular systems, including solutions, proteins, and composite materials, can be modeled using mixed-resolution representations, of which the quantum mechanics/molecular mechanics (QM/MM) approach has become the most widely used.…

Chemical Physics · Physics 2018-01-17 Anton V. Sinitskiy , Gregory A. Voth

We construct an efficient autonomous quantum-circuit design algorithm for creating efficient quantum circuits to simulate Hamiltonian many-body quantum dynamics for arbitrary input states. The resultant quantum circuits have optimal space…

Quantum Physics · Physics 2012-10-11 Sadegh Raeisi , Nathan Wiebe , Barry C. Sanders

Protein design is a technique to engineer proteins by modifying their sequence to obtain novel functionalities. In this method, amino acids in the sequence are permutated to find the low energy states satisfying the configuration. However,…

Quantitative Methods · Quantitative Biology 2023-05-10 Mohammad Hassan Khatami , Udson C. Mendes , Nathan Wiebe , Philip M. Kim

A molecule's geometry, also known as conformation, is one of a molecule's most important properties, determining the reactions it participates in, the bonds it forms, and the interactions it has with other molecules. Conventional…

Machine Learning · Computer Science 2020-01-01 Elman Mansimov , Omar Mahmood , Seokho Kang , Kyunghyun Cho

Optimizing high-degree of freedom robotic manipulators requires searching complex, high-dimensional configuration spaces, a task that is computationally challenging for classical methods. This paper introduces a quantum native framework…

Robotics · Computer Science 2025-10-30 Hassen Nigatu , Shi Gaokun , Li Jituo , Wang Jin , Lu Guodong , Howard Li

In the relentless efforts in enhancing medical diagnostics, the integration of state-of-the-art machine learning methodologies has emerged as a promising research area. In molecular biology, there has been an explosion of data generated…

Machine Learning · Computer Science 2024-05-17 Ibrahim Al-Hurani , Abedalrhman Alkhateeb , Salama Ikki

Quantum Key Distribution (QKD) networks require routing methodologies capable of jointly optimizing latency, secret key generation rate, congestion, finite capacity and operational security constraints under dynamically evolving traffic…

Quantum Physics · Physics 2026-05-28 Jose Luis Rosales

We present a deep reinforcement learning-based framework for autonomous microgrid management. tailored for remote communities. Using deep reinforcement learning and time-series forecasting models, we optimize microgrid energy dispatch…

Machine Learning · Computer Science 2025-09-05 Kenny Guo , Nicholas Eckhert , Krish Chhajer , Luthira Abeykoon , Lorne Schell

In this paper, we demonstrate a computationally efficient new approach based on deep learning (DL) techniques for analysis, design, and optimization of electromagnetic (EM) nanostructures. We use the strong correlation among features of a…

Machine Learning · Computer Science 2020-02-13 Yashar Kiarashinejad , Sajjad Abdollahramezani , Ali Adibi

A new self-learning algorithm for accelerated dynamics, reconnaissance metadynamics, is proposed that is able to work with a very large number of collective coordinates. Acceleration of the dynamics is achieved by constructing a bias…

Computational Physics · Physics 2010-10-15 Gareth A. Tribello , Michele Ceriotti , Michele Parrinello

Model calculations of nuclear properties are peformed using quantum computing algorithms on simulated and real quantum computers. The models are a realistic calculation of deuteron binding based on effective field theory, and a simplified…

Nuclear Theory · Physics 2022-05-12 Isaac Hobday , Paul D Stevenson , James Benstead

Machine Learning with deep neural networks has transformed computational approaches to scientific and engineering problems. Central to many of these advancements are precisely tuned neural architectures that are tailored to the domains in…

Quantum Physics · Physics 2025-04-23 Mathias Weiden , Justin Kalloor , John Kubiatowicz , Costin Iancu

A novel and highly efficient computational framework for reconstructing binary-type images suitable for models of various complexity seen in diverse biomedical applications is developed and validated. Efficiency in computational speed and…

Optimization and Control · Mathematics 2024-02-09 Paul R. Arbic , Vladislav Bukshtynov

Quantum key distribution (QKD) has often been hailed as a reliable technology for secure communication in cyber-physical microgrids. Even though unauthorized key measurements are not possible in QKD, attempts to read them can disturb…

Cryptography and Security · Computer Science 2024-05-21 Suman Rath , Neel Kanth Kundu , Subham Sahoo

The autoencoder is one of machine learning algorithms used for feature extraction by dimension reduction of input data, denoising of images, and prior learning of neural networks. At the same time, autoencoders using quantum computers are…

Quantum Physics · Physics 2019-06-05 Kodai Shiba , Katsuyoshi Sakamoto , Koichi Yamaguchi , Dinesh Bahadur Malla , Tomah Sogabe

Studying general quantum many-body systems is one of the major challenges in modern physics because it requires an amount of computational resources that scales exponentially with the size of the system.Simulating the evolution of a state,…

Quantum Physics · Physics 2018-07-03 Andrea Rocchetto , Edward Grant , Sergii Strelchuk , Giuseppe Carleo , Simone Severini

The QMol-grid package provides a suite of routines for performing quantum-mechanical simulations in atomic and molecular systems, currently implemented in one spatial dimension. It supports ground- and excited-state calculations for the…

Computational Physics · Physics 2024-11-19 Francois Mauger , Cristel Chandre
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