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With quantum resources a precious commodity, their efficient use is highly desirable. Quantum autoencoders have been proposed as a way to reduce quantum memory requirements. Generally, an autoencoder is a device that uses machine learning…

Quantum Physics · Physics 2019-02-18 Alex Pepper , Nora Tischler , Geoff J. Pryde

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

As we continue to find applications where the currently available noisy devices exhibit an advantage over their classical counterparts, the efficient use of quantum resources is highly desirable. The notion of quantum autoencoders was…

Quantum Physics · Physics 2022-07-08 Abhinav Anand , Jakob S. Kottmann , Alán Aspuru-Guzik

Classical autoencoders are neural networks that can learn efficient low dimensional representations of data in higher dimensional space. The task of an autoencoder is, given an input $x$, is to map $x$ to a lower dimensional point $y$ such…

Quantum Physics · Physics 2017-12-25 Jonathan Romero , Jonathan P. Olson , Alan Aspuru-Guzik

Variational Quantum Circuits (VQC) lie at the forefront of quantum machine learning research. Still, the use of quantum networks for real data processing remains challenging as the number of available qubits cannot accommodate a large…

Quantum Physics · Physics 2024-09-06 G. Maragkopoulos , A. Mandilara , A. Tsili , D. Syvridis

A major challenge in computational chemistry is the generation of novel molecular structures with desirable pharmacological and physiochemical properties. In this work, we investigate the potential use of autoencoder, a deep learning…

Machine Learning · Computer Science 2017-11-22 Thomas Blaschke , Marcus Olivecrona , Ola Engkvist , Jürgen Bajorath , Hongming Chen

Molecular dynamics simulations produce data with complex nonlinear dynamics. If the timestep behavior of such a dynamic system can be represented by a linear operator, future states can be inferred directly without expensive simulations.…

Machine Learning · Computer Science 2021-05-27 Willis Hoke , Daniel Shea , Stephen Casey

The quantum autoencoder is a recent paradigm in the field of quantum machine learning, which may enable an enhanced use of resources in quantum technologies. To this end, quantum neural networks with less nodes in the inner than in the…

Quantum Physics · Physics 2018-10-18 L. Lamata , U. Alvarez-Rodriguez , J. D. Martín-Guerrero , M. Sanz , E. Solano

Quantum machine learning methods often rely on fixed, hand-crafted quantum encodings that may not capture optimal features for downstream tasks. In this work, we study the power of quantum autoencoders in learning data-driven quantum…

Inspired by the success of deep learning techniques in the physical and chemical sciences, we apply a modification of an autoencoder type deep neural network to the task of dimension reduction of molecular dynamics data. We can show that…

Machine Learning · Statistics 2018-04-04 Christoph Wehmeyer , Frank Noé

In the model of quantum cloud computing, the server executes a computation on the quantum data provided by the client. In this scenario, it is important to reduce the amount of quantum communication between the client and the server. A…

Quantum Physics · Physics 2021-12-24 Yan Zhu , Ge Bai , Yuexuan Wang , Tongyang Li , Giulio Chiribella

Quantum geometrical molecular dynamics provides a quantum geometric picture for understanding reactive dynamics, especially excited-state conical intersection dynamics, and also a numerically exact method for strongly correlated…

Chemical Physics · Physics 2026-01-26 Mo Sha , Bing Gu

This paper focuses on addressing challenges posed by non-homogeneous unstructured grids, commonly used in Computational Fluid Dynamics (CFD). Their prevalence in CFD scenarios has motivated the exploration of innovative approaches for…

Computational Engineering, Finance, and Science · Computer Science 2024-05-08 Gabriele Immordino , Andrea Vaiuso , Andrea Da Ronch , Marcello Righi

Matched filtering for signal detection in noisy data requires template banks that capture variation in signal waveforms while minimizing computational cost. Dimensionality reduction of signal waveforms can be important for building…

General Relativity and Quantum Cosmology · Physics 2025-11-20 Giovanni Cabass , Digvijay Wadekar , Matias Zaldarriaga , Zihan Zhou

Computing atomic-scale properties of chemically disordered materials requires an efficient exploration of their vast configuration space. Traditional approaches such as Monte Carlo or Special Quasirandom Structures either entail sampling an…

Materials Science · Physics 2026-03-17 Maciej J. Karcz , Luca Messina , Eiji Kawasaki , Emeric Bourasseau

In recent years, machine learning and deep learning have driven advances in domains such as image classification, speech recognition, and anomaly detection by leveraging multi-layer neural networks to model complex data. Simultaneously,…

Quantum Physics · Physics 2025-11-25 Hibah Agha , Samuel Yen-Chi Chen , Huan-Hsin Tseng , Shinjae Yoo

Quantum machine learning consists in taking advantage of quantum computations to generate classical data. A potential application of quantum machine learning is to harness the power of quantum computers for generating classical data, a…

An autoencoder is used to optimize bit-to-symbol mappings for geometric constellation shaping. The mappings allow for net rate adaptivity without additional hardware complexity, while achieving up to 300km of transmission distance compared…

Signal Processing · Electrical Eng. & Systems 2023-01-04 Ognjen Jovanovic , Metodi P. Yankov , Francesco Da Ros , Darko Zibar

In this paper, we present an efficient adaptive multigrid strategy for the geometry optimization of large-scale three dimensional molecular mechanics. The resulting method can achieve significantly reduced complexity by exploiting the…

Computational Physics · Physics 2022-08-30 Kejie Fu , Mingjie Liao , Yangshuai Wang , Jianjun Chen , Lei Zhang

The de novo design of drug molecules is recognized as a time-consuming and costly process, and computational approaches have been applied in each stage of the drug discovery pipeline. Variational autoencoder is one of the computer-aided…

Quantum Physics · Physics 2021-12-24 Junde Li , Swaroop Ghosh
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