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Navigating the complex landscape of single-cell transcriptomic data presents significant challenges. Central to this challenge is the identification of a meaningful representation of high-dimensional gene expression patterns that sheds…

Quantitative Methods · Quantitative Biology 2023-12-13 Mu Qiao

We present Manifold Diffusion Fields (MDF), an approach that unlocks learning of diffusion models of data in general non-Euclidean geometries. Leveraging insights from spectral geometry analysis, we define an intrinsic coordinate system on…

Machine Learning · Computer Science 2024-01-23 Ahmed A. Elhag , Yuyang Wang , Joshua M. Susskind , Miguel Angel Bautista

Topological Data Analysis (TDA) is a recent approach to analyze data sets from the perspective of their topological structure. Its use for time series data has been limited to the field of financial time series primarily and as a method for…

Machine Learning · Computer Science 2019-06-18 Rodrigo Rivera-Castro , Polina Pilyugina , Alexander Pletnev , Ivan Maksimov , Wanyi Wyz , Evgeny Burnaev

Exploring the shape of point configurations has been a key driver in the evolution of TDA (short for topological data analysis) since its infancy. This survey illustrates the recent efforts to broaden these ideas to model spatial…

Computational Geometry · Computer Science 2024-06-07 Sebastiano Cultrera di Montesano , Ondrej Draganov , Herbert Edelsbrunner , Morteza Saghafian

With the development of high-throughput technologies, genomics datasets rapidly grow in size, including functional genomics data. This has allowed the training of large Deep Learning (DL) models to predict epigenetic readouts, such as…

Genomics · Quantitative Biology 2024-05-30 Alexander Rakowski , Remo Monti , Viktoriia Huryn , Marta Lemanczyk , Uwe Ohler , Christoph Lippert

Many real-world applications involve analyzing time-dependent phenomena, which are intrinsically functional, consisting of curves varying over a continuum (e.g., time). When analyzing continuous data, functional data analysis (FDA) provides…

Human-Computer Interaction · Computer Science 2023-06-19 Fnu Shilpika , Takanori Fujiwara , Naohisa Sakamoto , Jorji Nonaka , Kwan-Liu Ma

Topological Data Analysis (TDA) is a novel statistical technique, particularly powerful for the analysis of large and high dimensional data sets. Much of TDA is based on the tool of persistent homology, represented visually via persistence…

Applications · Statistics 2017-11-07 Sarit Agami , Robert J. Adler

Inferring user characteristics such as demographic attributes is of the utmost importance in many user-centric applications. Demographic data is an enabler of personalization, identity security, and other applications. Despite that, this…

Social and Information Networks · Computer Science 2017-12-21 Yehezkel S. Resheff , Moni Shahar

In this paper, a novel technique named random subspace two-dimensional LDA (RS-2DLDA) is developed for face recognition. This approach offers a number of improvements over the random subspace two-dimensional PCA (RS2DPCA) framework…

Computer Vision and Pattern Recognition · Computer Science 2017-11-03 Garrett Bingham

Multiscale transforms have become a key ingredient in many data processing tasks. With technological development, we observe a growing demand for methods to cope with non-linear data structures such as manifold values. In this paper, we…

Numerical Analysis · Mathematics 2021-08-17 Wael Mattar , Nir Sharon

Federated learning (FL) for histopathology image segmentation involving multiple medical sites plays a crucial role in advancing the field of accurate disease diagnosis and treatment. However, it is still a task of great challenges due to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Yuan Zhang , Yaolei Qi , Xiaoming Qi , Lotfi Senhadji , Yongyue Wei , Feng Chen , Guanyu Yang

Complex data objects arise in many areas of modern science including evolutionary biology, nueroscience, dynamics of gene expression and medical imaging. Object oriented data analysis (OODA) is the statistical analysis of datasets of…

Other Statistics · Statistics 2014-11-12 Sean Skwerer

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Manifold learning is a popular and quickly-growing subfield of machine learning based on the assumption that one's observed data lie on a low-dimensional manifold embedded in a higher-dimensional space. This thesis presents a mathematical…

Machine Learning · Computer Science 2020-11-04 Luke Melas-Kyriazi

Federated Domain Adaptation (FDA) is a federated learning (FL) approach that improves model performance at the target client by collaborating with source clients while preserving data privacy. FDA faces two primary challenges: domain shifts…

Machine Learning · Computer Science 2025-09-16 Mrinmay Sen , Ankita Das , Sidhant Nair , C Krishna Mohan

Monocular depth estimation (MDE) has attracted intense study due to its low cost and critical functions for robotic tasks such as localization, mapping and obstacle detection. Supervised approaches have led to great success with the advance…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Shao-Yuan Lo , Wei Wang , Jim Thomas , Jingjing Zheng , Vishal M. Patel , Cheng-Hao Kuo

Personalized facial expression recognition (FER) involves adapting a machine learning model using samples from labeled sources and unlabeled target domains. Given the challenges of recognizing subtle expressions with considerable…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Muhammad Osama Zeeshan , Marco Pedersoli , Alessandro Lameiras Koerich , Eric Granger

This paper proposes an approach to learn generic multi-modal mesh surface representations using a novel scheme for fusing texture and geometric data. Our approach defines an inverse mapping between different geometric descriptors computed…

Computer Vision and Pattern Recognition · Computer Science 2019-04-10 Bilal Taha , Munawar Hayat , Stefano Berretti , Naoufel Werghi

Mask-based annotation of medical images, especially for 3D data, is a bottleneck in developing reliable machine learning models. Using minimal-labor user interactions (UIs) to guide the annotation is promising, but challenges remain on best…

Computer Vision and Pattern Recognition · Computer Science 2020-09-08 Ashwin Raju , Zhanghexuan Ji , Chi Tung Cheng , Jinzheng Cai , Junzhou Huang , Jing Xiao , Le Lu , ChienHung Liao , Adam P. Harrison

Facial Attribute Manipulation (FAM) aims to aesthetically modify a given face image to render desired attributes, which has received significant attention due to its broad practical applications ranging from digital entertainment to…

Computer Vision and Pattern Recognition · Computer Science 2022-10-25 Yunfan Liu , Qi Li , Qiyao Deng , Zhenan Sun , Ming-Hsuan Yang
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