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In a number of estimation problems in bioinformatics, accuracy measures of the target problem are usually given, and it is important to design estimators that are suitable to those accuracy measures. However, there is often a discrepancy…

Quantitative Methods · Quantitative Biology 2013-05-21 Michiaki Hamada , Hisanori Kiryu , Wataru Iwasaki , Kiyoshi Asai

Biology-derived algorithms are an important part of computational sciences, which are essential to many scientific disciplines and engineering applications. Many computational methods are derived from or based on the analogy to natural…

Optimization and Control · Mathematics 2010-03-10 Xin-She Yang

Genetic algorithms are modeled after the biological evolutionary processes that use natural selection to select the best species to survive. They are heuristics based and low cost to compute. Genetic algorithms use selection, crossover, and…

Neural and Evolutionary Computing · Computer Science 2020-05-28 Mee Seong Im , Venkat R. Dasari

This paper made a short review of Cloud Computing and Big Data, and discussed the portability of general data mining algorithms to Cloud Computing platform. It revealed the Cloud Computing platform based on Map-Reduce cannot solve all the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-02-07 Yong Wang , Ya Wei Zhao

Co-clustering simultaneously clusters rows and columns, revealing more fine-grained groups. However, existing co-clustering methods suffer from poor scalability and cannot handle large-scale data. This paper presents a novel and scalable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Zihan Wu , Zhaoke Huang , Hong Yan

As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to…

Machine Learning · Computer Science 2019-02-26 Vivek Kumar , Brojo Kishore Mishra , Manuel Mazzara , Dang N. H. Thanh , Abhishek Verma

Artificial intelligence has made remarkable progress in handling complex tasks, thanks to advances in hardware acceleration and machine learning algorithms. However, to acquire more accurate outcomes and solve more complex issues,…

Machine Learning · Computer Science 2023-09-12 Mohammad Dehghani , Zahra Yazdanparast

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

Quantitative Methods · Quantitative Biology 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman

Profiling techniques are used extensively at different parts of the computing stack to achieve many goals. One major goal is to make a piece of software execute more efficiently on a specific hardware platform, where efficiency spans…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-11-07 Chris Quackenbush , Mohamed Zahran

Modern retrieval systems are often driven by an underlying machine learning model. The goal of such systems is to identify and possibly rank the few most relevant items for a given query or context. Thus, such systems are typically…

Machine Learning · Statistics 2017-03-02 Elad ET. Eban , Mariano Schain , Alan Mackey , Ariel Gordon , Rif A. Saurous , Gal Elidan

We introduce computational causal inference as an interdisciplinary field across causal inference, algorithms design and numerical computing. The field aims to develop software specializing in causal inference that can analyze massive…

Computation · Statistics 2020-07-22 Jeffrey C. Wong

Learning interpretable models has become a major focus of machine learning research, given the increasing prominence of machine learning in socially important decision-making. Among interpretable models, rule lists are among the best-known…

Machine Learning · Computer Science 2024-06-19 Leonardo Pellegrina , Fabio Vandin

In the emerging era of big data, larger available clinical datasets and computational advances have sparked a massive interest in machine learning-based approaches. The number of manuscripts related to machine learning or artificial…

Machine Learning · Statistics 2020-06-29 Julius M. Kernbach , Victor E. Staartjes

A variety of large-scale machine learning problems can be cast as instances of constrained submodular maximization. Existing approaches for distributed submodular maximization have a critical drawback: The capacity - number of instances…

Machine Learning · Statistics 2016-06-01 Mario Lucic , Olivier Bachem , Morteza Zadimoghaddam , Andreas Krause

Data-driven algorithm design is a paradigm that uses statistical and machine learning techniques to select from a class of algorithms for a computational problem an algorithm that has the best expected performance with respect to some…

Machine Learning · Computer Science 2024-06-05 Hongyu Cheng , Sammy Khalife , Barbara Fiedorowicz , Amitabh Basu

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

Present day machine learning is computationally intensive and processes large amounts of data. It is implemented in a distributed fashion in order to address these scalability issues. The work is parallelized across a number of computing…

Machine Learning · Computer Science 2017-03-28 Alexander Ulanov , Andrey Simanovsky , Manish Marwah

Bio-inspired algorithms utilize natural processes such as evolution, swarm behavior, foraging, and plant growth to solve complex, nonlinear, high-dimensional optimization problems. However, a plethora of these algorithms require a more…

In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists. Of interest…

Methodology · Statistics 2011-04-13 Xiaodan Fan , Yuan Yuan , Jun S. Liu