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An alternative approach to ultrasound computed tomography (USCT) for medical imaging is proposed, with the intent to (i) shorten acquisition time for devices with a large number of emitters, (ii) eliminate the calibration step, and (iii)…
In X-ray imaging, photons are transmitted through and absorbed by the subject, but are also scattered in significant quantities. Previous attempts to use scattered photons for biological imaging used pencil or fan beam illumination. Here we…
Hybrid photon counting detectors (HPCDs) have unlocked new capabilities for x-ray-based measurements at synchrotrons around the world in the last 30 years. By leveraging independently optimized sensor and readout layers, they offer high…
Compact coherent x-ray sources have been the focus of extensive research efforts over the past decades. As a result, several novel schemes like optical and nano-undulators for generating x-ray emissions in "table-top" setups are proposed,…
An imaging system based on single photon counting and compressive sensing (ISSPCCS) is developed to reconstruct a sparse image in absolute darkness. The single photon avalanche detector and spatial light modulator (SLM) of aluminum…
X-rays have widespread applications in science and industry, but developing a simple, compact, and high-quality X-ray source remains a challenge. Our collaboration has explored the possible use of channeling radiation driven by a 50 MeV…
Quantifying material mass and electron density from computed tomography (CT) reconstructions can be highly valuable in certain medical practices, such as radiation therapy planning. However, uniquely parameterising the X-ray attenuation in…
Spectral CT has great potential for a variety of clinical applications due to the improved material discrimination with respect to conventional CT. Many clinical and preclinical spectral CT systems have two spectral channels for dual-energy…
We present a workbench for the study of real-time quantum imaging by measuring the frame-by-frame quantum noise reduction of multi-spatial-mode twin beams generated by four wave mixing in Rb vapor. Exploiting the multiple spatial modes of…
We describe a feasible implementation of a novel X-ray detector for highly energetic x-ray photons with a large solid angle coverage, optimal for the detection of Compton x-ray scattered photons. The device consists of a 20~cm-thick…
Photon-Counting Computed Tomography (PCCT) is a novel imaging modality that simultaneously acquires volumetric data at multiple X-ray energy levels, generating separate volumes that capture energy-dependent attenuation properties.…
The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve…
X-ray phase contrast tomography (XPCT) is widely used for 3D imaging of objects with weak contrast in X-ray absorption index but strong contrast in refractive index decrement. To reconstruct an object imaged using XPCT, phase retrieval…
We describe a full-field coherent imaging approach suitable for hard X-rays based on a classical (i.e. Galilean) X-ray microscope. The method combines a series of low-resolution images acquired at different transverse lens positions into a…
Mask-based lensless imagers use simple optics and computational reconstruction to design compact form factor cameras with compressive imaging ability. However, these imagers generally suffer from poor reconstruction quality. Here, we…
In clinical CT system, the x-ray tube emits polychromatic x-rays, and the x-ray detectors operate in the current-integrating mode. This physical process is accurately described by an energy-dependent non-linear integral equation. However,…
We report on the design, construction and operation of a low background x-ray detection line composed of a shielded Micromegas (micromesh gaseous structure) detector of the microbulk technique. The detector is made from radiopure materials…
We present a practical experimental realization of transmission x-ray ghost imaging using synchrotron light. Hard x-rays from an undulator were split by a Si 200 crystal in Laue geometry to produce two copies of a speckled incident beam.…
Future hard (10 -100 keV) X-ray telescopes (SIMBOL-X, Con-X, HEXIT-SAT, XEUS) will implement focusing optics with multilayer coatings: in view of the production of these optics we are exploring several deposition techniques for the…
While model-based reconstruction methods have been successfully applied to flat-panel cone-beam CT (FP-CBCT) systems, typical implementations ignore both spatial correlations in the projection data as well as system blurs due to the…