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Incorrect usage of $p$-values, particularly within the context of significance testing using the arbitrary .05 threshold, has become a major problem in modern statistical practice. The prevalence of this problem can be traced back to the…

Methodology · Statistics 2021-07-19 MaryLena Bleile

We propose novel methodology for testing equality of model parameters between two high-dimensional populations. The technique is very general and applicable to a wide range of models. The method is based on sample splitting: the data is…

Methodology · Statistics 2013-01-17 Nicolas Städler , Sach Mukherjee

Penalized regression models such as the Lasso have proved useful for variable selection in many fields - especially for situations with high-dimensional data where the numbers of predictors far exceeds the number of observations. These…

Methodology · Statistics 2014-03-19 Kasper Brink-Jensen , Claus Thorn Ekstrøm

Prediction-powered inference is a framework for performing valid statistical inference when an experimental dataset is supplemented with predictions from a machine-learning system. The framework yields simple algorithms for computing…

Machine Learning · Statistics 2023-11-10 Anastasios N. Angelopoulos , Stephen Bates , Clara Fannjiang , Michael I. Jordan , Tijana Zrnic

Learning is a distinctive feature of intelligent behaviour. High-throughput experimental data and Big Data promise to open new windows on complex systems such as cells, the brain or our societies. Yet, the puzzling success of Artificial…

Machine Learning · Computer Science 2022-05-04 Matteo Marsili , Yasser Roudi

In the field of multiple hypothesis testing, combining p-values represents a fundamental statistical method. The Cauchy combination test (CCT) (Liu and Xie, 2020) excels among numerous methods for combining p-values with powerful and…

Methodology · Statistics 2024-10-17 Yanyan Ouyang , Xingwei Liu , Lixing Zhu , Wangli Xu

This essay looks at decision-making with interval-valued probability measures. Existing decision methods have either supplemented expected utility methods with additional criteria of optimality, or have attempted to supplement the…

Artificial Intelligence · Computer Science 2013-04-15 Ronald P. Loui

Given a large pool of unlabelled data and a smaller amount of labels, prediction-powered inference (PPI) leverages machine learning predictions to increase the statistical efficiency of confidence interval procedures based solely on…

Machine Learning · Statistics 2025-10-27 Valentin Kilian , Stefano Cortinovis , François Caron

Hypothesis tests calibrated by (re)sampling methods (such as permutation, rank and bootstrap tests) are useful tools for statistical analysis, at the computational cost of requiring Monte-Carlo sampling for calibration. It is common and…

Methodology · Statistics 2024-09-30 Ivo V. Stoepker , Rui M. Castro

What are the criteria that a measure of statistical evidence should satisfy? It is argued that a measure of evidence should be consistent. Consistency is an asymptotic criterion: the probability that if a measure of evidence in data…

Statistics Theory · Mathematics 2011-11-22 M. Grendar

Which type of statistical uncertainty -- statistical (in)significance with a p-value, or a Bayesian probability -- enables people to see the continuous nature of uncertainty more clearly in a policymaking context? An original survey…

Other Statistics · Statistics 2024-02-20 Akisato Suzuki

Data valuation has become an increasingly significant discipline in data science due to the economic value of data. In the context of machine learning (ML), data valuation methods aim to equitably measure the contribution of each data point…

Machine Learning · Computer Science 2023-06-13 Xiang Li , Haocheng Xia , Jinfei Liu

We define some appropriate statistical quantities that indicate the physical significance (reliability) of confidence intervals in the framework of both Frequentist and Bayesian statistical theories. We consider the expectation value of the…

High Energy Physics - Experiment · Physics 2009-10-31 C. Giunti , M. Laveder

In multivariate pattern analysis of neuroimaging data, 'second-level' inference is often performed by entering classification accuracies into a $t$-test vs chance level across subjects. We argue that while the random-effects analysis…

Neurons and Cognition · Quantitative Biology 2016-08-11 Carsten Allefeld , Kai Görgen , John-Dylan Haynes

In this paper we present a new measure for the overlap of two density functions which provides motivation and interpretation currently lacking with benchmark measures based on the proportion of similar response, also known as the overlap…

Methodology · Statistics 2021-06-08 Stephen G Walker

We discuss problems the null hypothesis significance testing (NHST) paradigm poses for replication and more broadly in the biomedical and social sciences as well as how these problems remain unresolved by proposals involving modified…

Methodology · Statistics 2021-07-21 Blakeley B. McShane , David Gal , Andrew Gelman , Christian Robert , Jennifer L. Tackett

Corrected confidence intervals are developed for the mean of the second component of a bivariate normal process when the first component is being monitored sequentially. This is accomplished by constructing a first approximation to a…

Statistics Theory · Mathematics 2007-06-13 R. C. Weng , D. S. Coad

In this paper, we investigate the impact of high-dimensional Principal Component (PC) adjustments on inferring the effects of variables on outcomes, with a focus on applications in genetic association studies where PC adjustment is commonly…

Statistics Theory · Mathematics 2025-06-30 Sohom Bhattacharya , Rounak Dey , Rajarshi Mukherjee

Classical tests for a difference in means control the type I error rate when the groups are defined a priori. However, when the groups are instead defined via clustering, then applying a classical test yields an extremely inflated type I…

Methodology · Statistics 2022-11-01 Lucy L. Gao , Jacob Bien , Daniela Witten

We seek to conduct statistical inference for a large collection of primary parameters, each with its own nuisance parameters. Our approach is partially Bayesian, in that we treat the primary parameters as fixed while we model the nuisance…

Methodology · Statistics 2025-12-10 Nikolaos Ignatiadis , Li Ma
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