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Mirror symmetry is among the most fundamental concepts of physics and its spontaneous breaking at the molecular level allows chiral molecules to exist in two enantiomers that are mirror images of each other. The majority of chiro-optical…

Optics · Physics 2021-09-29 Alessandro Ciattoni

We optically trap freestanding single metallic chiral nanoparticles using a standing-wave optical tweezer. We also incorporate within the trap a polarimetric setup that allows to perform in situ chiral recognition of single enantiomers.…

Chirality is ubiquitous in nature and fundamental in science, from particle physics to metamaterials.The most established technique of chiral discrimination - photoabsorption circular dichroism - relies on the magnetic properties of a…

The separation of physical forces acting on the tip of a magnetic force microscope (MFM) is essential for correct magnetic imaging. Electrostatic forces can be modulated by varying the tip-sample potential and minimized to map the local…

We propose an enantio-detection method of chiral molecules in a cavity with external drive. The chiral molecules are coupled with a quantized cavity field and two classical light fields to form the cyclic three-level systems. The…

Quantum Physics · Physics 2022-02-15 Yu-Yuan Chen , Jian-Jian Cheng , Chong Ye , Yong Li

Optical nanofibers are waveguides known for their unique property to produce intense evanescent fields which have subwavelength transverse confinement easily extendable over thousands of wavelengths along the fiber axis. Moreover,…

Recently, we proposed a metasurface design for chiral sensing that (i) results in enhanced chiroptical signals by more than two orders of magnitude for ultrathin, subwavelength, chiral samples over a uniform and accessible area, (ii) allows…

Optics · Physics 2021-08-18 Sotiris Droulias , Lykourgos Bougas

Chiral discrimination of enantiomeric biomolecules is vital in chemistry, biology, and medicine. Conventional methods, relying on circularly polarized light, face weak chiroptical signals and potential photodamage. Despite extensive efforts…

Quantum Physics · Physics 2026-01-21 Yiquan Yang , Xiaolong Hu , Wei Du , Shuhe Wu , Peiyu Yang , Guzhi Bao , Weiping Zhang

A simple yet effective achiral platform using elliptical nanoholes for chiroptical analysis is demonstrated. Under linearly polarized excitation, an elliptical nanohole in a thin gold film can generate a localized chiral optical field for…

Optics · Physics 2021-01-13 Zhan-Hong Lin , Jiwei Zhang , Jer-Shing Huang

Chiral spectroscopy is a powerful technique that enables to identify the chirality of matter through optical means. So far, experiments to check the chirality of matter or nanostructures have been carried out using free-space propagating…

Optics · Physics 2019-11-26 J. Enrique Vázquez-Lozano , Alejandro Martínez

Optically active achiral metasurfaces offer a promising way to detect chiral molecules based on chiroptic methods. The combination of plasmonic enhanced circular dichroism and reversible optical activity would boost the sensitivity and…

The enhancement of the inherently weak optical activity of solvated molecules by superchiral fields, crucial for detecting their chirality, is a research frontier of photonics and the basis of novel chiroptical detection schemes. Here, we…

Detecting and controlling the chirality of materials play an essential role in exploring nature, providing new avenues for material creation, discrimination, and manipulation. In such tasks, chiral reagents are essential in defining or…

Optimally-chiral electromagnetic fields with maximized helicity density, recently introduced in [1], enable chirality characterization of optically small nanoparticles. Here, we demonstrate a technique to obtain optimally-chiral nearfields…

Applied Physics · Physics 2020-12-02 Mina Hanifeh , Mohammad Albooyeh , Filippo Capolino

The detection and discrimination of molecular chirality are essential for advancing pharmaceutical and biological applications. While nanophotonic platforms offer a route to enhance chiral light-matter interactions, existing device concepts…

Optics · Physics 2025-11-21 Zhongjun Jiang , Soyaib Sohag , You Zhou

A highly-efficient method for optical detection and separation of left- and right-handed chiral molecules is presented. The method utilizes a closed-loop three-state system in which the population dynamics depends on the phases of the three…

Quantum Physics · Physics 2019-05-08 Nikolay V. Vitanov , Michael Drewsen

Distinguishing between enantiomers is crucial in the study of chiral molecules in chemistry and pharmacology. Many optical approaches rely on enantiospecific cyclic electric-dipole transitions induced by three microwave or laser beams.…

Quantum Physics · Physics 2025-12-11 Fen Zou , Yong Li , Peng Zhang

Chiral nanomaterials offer intriguing possibilities for novel electronic and chemical applications. Here, we report the discovery of an enantiomer-selective magnetoresistance effect in chiral gold nanocrystals. Based on precise control of…

Mesoscale and Nanoscale Physics · Physics 2025-03-03 Fengxia Wu , Ying Wang , Yufei Zhao , Zhenyu Yang , Yu Tian , Zuoti Xie , Wenxin Niu , Binghai Yan , Cunlan Guo

Tip enhanced IR spectra and imaging have been widely used in cutting-edge studies for the in-depth understanding of the composition, structure and function of interfaces at the nanoscale. However, molecular monolayer sensitivity has only…

Chiral optical forces present an exciting avenue into the separation of enantiomers in an all-optical fashion. In this work, we explore via numerical simulations and analytical calculations the feasibility of the separation of chiral…