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A new method is introduced for calibrating lateral force as measured by an atomic force microscope (AFM), making use of both an interferometric detector and an optical beam detector on the same instrument. The method may be implemented…

Mesoscale and Nanoscale Physics · Physics 2025-03-25 Joel Lefever , Aleksander Labuda , Roger Proksch

Atomic force microscopy is based on tip sample interaction, which is determined by the properties of tip and sample. Unfortunately, in particular in ambient conditions the tip as well as the sample are contaminated, and it is not clear how…

Mesoscale and Nanoscale Physics · Physics 2017-12-19 J. Sánchez , L. Almonte , J. Colchero

Knowledge of surface forces is the key to understanding a large number of processes in fields ranging from physics to material science and biology. The most common method to study surfaces is dynamic atomic force microscopy (AFM). Dynamic…

Mesoscale and Nanoscale Physics · Physics 2013-02-06 Daniel Platz , Daniel Forchheimer , Erik A. Tholen , David B. Haviland

The aim of this article is to provide a complete analysis of the behavior of a noncontact atomic force microscope (NC-AFM). We start with a review of the equations of motion of a tip interacting with a surface in which the stability…

Atomic and Molecular Clusters · Physics 2016-08-16 Gérard Couturier , Rodolphe Boisgard , Laurent Nony , Jean-Pierre Aimé

Despite being the dominant force of nature on large scales, gravity remains relatively elusive to experimental measurement. Many questions remain, such as its behavior at small scales or its role in phenomena ascribed to dark matter and…

Atomic Physics · Physics 2024-08-19 Cristian D. Panda , Matthew J. Tao , Miguel Ceja , Holger Müller

Atomic Force Microscopy (AFM) conventional static force curves and Force Feedback Microscopy (FFM) force curves acquired with the same cantilever at the solid/air and solid/liquid interfaces are here compared. The capability of the FFM to…

Mesoscale and Nanoscale Physics · Physics 2013-06-13 Luca Costa , Mario S. Rodrigues , Simon Carpentier , Pieter Jan van Zwol , Joel Chevrier , Fabio Comin

When measuring quadratic values representative of random fluctuations, such as the thermal noise of Atomic Force Microscopy (AFM) cantilevers, the background measurement noise cannot be averaged to zero. We present a signal processing…

Instrumentation and Detectors · Physics 2017-03-09 Basile Pottier , Ludovic Bellon

Atomic force microscopy (AFM) is widely used to measure surface topography of solid, soft, and living matter at the nanoscale. Moreover, by mapping forces as a function of distance to the surface, AFM can provide a wealth of information…

We discuss the influence of external forces on the motion of the tip in dynamic atomic force microscopy (AFM). First, a compact solution for the steady-state problem is derived employing a Fourier approach. Founding on this solution, we…

Mesoscale and Nanoscale Physics · Physics 2019-01-29 Tino Wagner

The native structures of proteins, except for notable exceptions of intrinsically disordered proteins, in general take their most stable conformation in the physiological condition to maintain their structural framework so that their…

Biomolecules · Quantitative Biology 2021-10-26 Lyman Monroe , Daisuke Kihara

We examine the mechanical eigenmodes of a quartz tuning fork (QTF) for the purpose of facilitat- ing its use as a probe for multi-frequency atomic force microscopy (AFM). We perform simulations based on the three-dimensional finite element…

Instrumentation and Detectors · Physics 2017-03-08 Bongsu Kim , Junghoon Jahng , Ryan Muhammad Khan , Sung Park , Eric O. Potma

Recent frequency-modulated atomic force microscopy (FM-AFM) can measure three-dimensional force distribution between a probe and a sample surface in liquid. The force distribution is, in the present circumstances, assumed to be solvation…

Data Analysis, Statistics and Probability · Physics 2013-12-02 Ken-ich Amano , Ohgi Takahash

We investigate the capillary force that applies on a tilted cylinder as a function of its dipping angle i, using a home-built tilting Atomic Force Microscope (AFM) with custom made probes. A micrometric-size rod is glued at the end of an…

Soft Condensed Matter · Physics 2017-02-23 Sebastien Kosgodagan Acharige , Justine Laurent , Audrey Steinberger

Measurements of the deflection induced by thermal noise have been performed on a rectangular atomic force microscope cantilever in air. The detection method, based on polarization interferometry, can achieve a resolution of 1E-14 m/rtHz in…

Statistical Mechanics · Physics 2009-11-17 Pierdomenico Paolino , Bruno Tiribilli , Ludovic Bellon

Surface electric noise, i.e., the non-uniform distribution of charges and potentials on a surface, poses a great experimental challenge in modern precision force measurements. Such a challenge is encountered in a number of different…

Quantum Physics · Physics 2023-05-03 W. J. Kim , U. D. Schwarz

We report a new spin manipulation protocol for periodically reversing the sample magnetization for Magnetic Resonance Force Microscopy. The protocol modulates the microwave excitation frequency synchronously with the position of the…

Mesoscale and Nanoscale Physics · Physics 2011-12-12 K. C. Fong , P. Banerjee , Yu. Obukhov , D. V. Pelekhov , P. C. Hammel

Tapping mode atomic force microscopy is a standard technique for inspection and analysis at the nanometer scale. The understanding of the non-linear dynamics of the system due to the tip sample interaction is an important prerequisite for a…

Instrumentation and Detectors · Physics 2007-05-23 Robert W. Stark

Dynamic-mode atomic force microscopy (AFM) in liquid remains complicated due to the strong viscous damping of the cantilever resonance. Here we show that a high-quality resonance (Q>20) can be achieved in aqueous solution by attaching a…

Instrumentation and Detectors · Physics 2015-05-14 Sebastian Hoof , Nitya Nand Gosvami , Bart W. Hoogenboom

Tapping mode atomic force microscopy (AFM), also known as amplitude modulated (AM) or AC mode, is a proven, reliable and gentle imaging mode with widespread applications. Over the several decades that tapping mode has been in use,…

Mesoscale and Nanoscale Physics · Physics 2017-09-07 Marta Kocun , Aleksander Labuda , Waiman Meinhold , Irene Revenko , Roger Proksch

Atomic force microscopes have proved to be fundamental research tools in many situations where a gentle imaging process is required, and in a variety of environmental conditions, such as the study of biological samples. Among the possible…

Systems and Control · Computer Science 2023-01-05 Marco Coraggio , Martin Homer , Oliver D. Payton , Mario di Bernardo