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The diagnosis of prostate cancer is challenging due to the heterogeneity of its presentations, leading to the over diagnosis and treatment of non-clinically important disease. Accurate diagnosis can directly benefit a patient's quality of…

By 2025, holotomography (HT) has matured from a niche optical modality into a versatile platform for quantitative, label-free imaging in biomedicine. By reconstructing the three-dimensional refractive-index (RI) distribution of cells and…

Biological Physics · Physics 2026-01-07 YongKeun Park

Histopathology refers to the examination by a pathologist of biopsy samples. Histopathology images are captured by a microscope to locate, examine, and classify many diseases, such as different cancer types. They provide a detailed view of…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Naira Elazab , Hassan Soliman , Shaker El-Sappagh , S. M. Riazul Islam , Mohammed Elmogy

Histopathological images (HIs) are the gold standard for evaluating some types of tumors for cancer diagnosis. The analysis of such images is not only time and resource consuming, but also very challenging even for experienced pathologists,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jonathan de Matos , Steve Tsham Mpinda Ataky , Alceu de Souza Britto , Luiz Eduardo Soares de Oliveira , Alessandro Lameiras Koerich

MRI (Magnetic Resonance Imaging) is a technique used to analyze and diagnose the problem defined by images like cancer or tumor in a brain. Physicians require good contrast images for better treatment purpose as it contains maximum…

Computer Vision and Pattern Recognition · Computer Science 2020-03-17 Sakshi Patel , Bharath K P , Rajesh Kumar Muthu

Conventional haematoxylin, eosin and saffron (HES) histopathology, currently the gold-standard for pathological diagnosis of cancer, requires extensive sample preparations that are achieved within time scales that are not compatible with…

Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews…

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Histopathological imaging is vital for cancer research and clinical practice, with multiplexed Immunofluorescence (MxIF) and Hematoxylin and Eosin (H&E) providing complementary insights. However, aligning different stains at the cell level…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jun Jiang , Raymond Moore , Brenna Novotny , Leo Liu , Zachary Fogarty , Ray Guo , Markovic Svetomir , Chen Wang

Histopathologic Images (HI) are the gold standard for evaluation of some tumors. However, the analysis of such images is challenging even for experienced pathologists, resulting in problems of inter and intra observer. Besides that, the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Jonathan de Matos , Alceu de Souza Britto , Luiz E. S. Oliveira , Alessandro L. Koerich

Non-invasive imaging plays a crucial role in the early detection, diagnosis, and treatment of numerous medical conditions. This article discusses recent advancements in coherent imaging techniques.The article begins by discussing the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-04 Boyang Li

Medical imaging plays an important role in the medical sector in identifying diseases. X-ray, computed tomography (CT) scans, and magnetic resonance imaging (MRI) are a few examples of medical imaging. Most of the time, these imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Mosabbir Bhuiyan , MD Abdullah Al Nasim , Sarwar Saif , Kishor Datta Gupta , Md Jahangir Alam , Sajedul Talukder

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several indications has yielded improved prognosis for cases where traditional therapy has shown limited efficiencey. However, many patients still fail to…

Medical Physics · Physics 2023-08-08 Nikita Vladimirov , Or Perlman

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Label-free imaging approaches seek to simplify and augment histopathologic assessment by replacing the current practice of staining by dyes to visualize tissue morphology with quantitative optical measurements. Quantitative phase imaging…

Histopathology, the current gold standard for cancer diagnosis, involves the manual examination of tissue samples after chemical staining, a time-consuming process requiring expert analysis. Raman spectroscopy is an alternative, stain-free…

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Tissue biopsy evaluation in the clinic is in need of quantitative disease markers for diagnosis and, most importantly, prognosis. Among the new technologies, quantitative phase imaging (QPI) has demonstrated promise for histopathology…

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady
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