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Topology applied to real world data using persistent homology has started to find applications within machine learning, including deep learning. We present a differentiable topology layer that computes persistent homology based on level set…

The Persistent Homology Transform (PHT) summarizes a shape in $\mathbb{R}^m$ by collecting persistence diagrams obtained from linear height filtrations in all directions on $\mathbb{S}^{m-1}$. It enjoys strong theoretical guarantees,…

Computational Geometry · Computer Science 2026-04-10 Michael Kerber , Elena Xinyi Wang

A central problem in data-driven scientific inquiry is how to interpret structure in noisy, high-dimensional data. Topological data analysis (TDA) provides a solution via persistent homology, which encodes features of interest as…

Algebraic Topology · Mathematics 2026-02-04 Christian Lentz , Gregory Henselman-Petrusek , Lori Ziegelmeier

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Persistent topological Laplacians constitute a new class of tools in topological data analysis (TDA). They are motivated by the necessity to address challenges encountered in persistent homology when handling complex data. These Laplacians…

Algebraic Topology · Mathematics 2024-12-12 Xiaoqi Wei , Guo-Wei Wei

One of the primary areas of interest in applied algebraic topology is persistent homology, and, more specifically, the persistence diagram. Persistence diagrams have also become objects of interest in topological data analysis. However,…

Methodology · Statistics 2018-04-06 Eric Berry , Yen-Chi Chen , Jessi Cisewski-Kehe , Brittany Terese Fasy

The predictions of mean-field electrodynamics can now be probed using direct numerical simulations of random flows and magnetic fields. When modelling astrophysical MHD, it is important to verify that such simulations are in agreement with…

Data Analysis, Statistics and Probability · Physics 2018-09-12 Irina Makarenko , Paul Bushby , Andrew Fletcher , Robin Henderson , Nikolay Makarenko , Anvar Shukurov

Features such as photon rings, jets, or hot. spots can leave particular topological signatures in a black hole image. As such, topological data analysis can be used to characterize images resulting from high resolution observations…

High Energy Astrophysical Phenomena · Physics 2022-10-11 Pierre Christian , Chi-kwan Chan , Anthony Hsu , Feryal Ozel , Dimitrios Psaltis , Iniyan Natarajan

Persistent homology (PH) is one of the most popular methods in Topological Data Analysis. Even though PH has been used in many different types of applications, the reasons behind its success remain elusive; in particular, it is not known…

Algebraic Topology · Mathematics 2023-01-18 Renata Turkeš , Guido Montúfar , Nina Otter

The existence of characteristic structure, or shape, in complex data sets has been recognized as increasingly important for mathematical data analysis. This realization has motivated the development of new tools such as persistent homology…

Computer Vision and Pattern Recognition · Computer Science 2016-07-12 Sofya Chepushtanova , Michael Kirby , Chris Peterson , Lori Ziegelmeier

We present a new method for the statistical process control of lattice structures using tools from Topological Data Analysis. Motivated by applications in additive manufacturing, such as aerospace components and biomedical implants, where…

Methodology · Statistics 2025-10-15 Yulin An , Xueqi Zhao , Enrique del Castillo

The persistence diagram is an increasingly useful tool from Topological Data Analysis, but its use alongside typical machine learning techniques requires mathematical finesse. The most success to date has come from methods that map…

Computational Geometry · Computer Science 2023-03-15 Jose A. Perea , Elizabeth Munch , Firas A. Khasawneh

Persistent homology is a branch of computational algebraic topology that studies shapes and extracts features over multiple scales. In this paper, we present an unsupervised approach that uses persistent homology to study divergent behavior…

In this article, we introduce a Topological Data Analysis (TDA) pipeline for neural spike train data. Understanding how the brain transforms sensory information into perception and behavior requires analyzing coordinated neural population…

Methodology · Statistics 2025-12-10 Cagatay Ayhan , Audrey N. Nash , Roberto Vincis , Martin Bauer , Richard Bertram , Tom Needham

Sparse systems are usually parameterized by a tuning parameter that determines the sparsity of the system. How to choose the right tuning parameter is a fundamental and difficult problem in learning the sparse system. In this paper, by…

Methodology · Statistics 2019-01-18 Moo K. Chung , Jamie L. Hanson , Jieping Ye , Richard J. Davidson , Seth D. Pollak

We introduce \emph{topological density estimation} (TDE), in which the multimodal structure of a probability density function is topologically inferred and subsequently used to perform bandwidth selection for kernel density estimation. We…

Methodology · Statistics 2022-03-10 Steve Huntsman

Biomolecular structure comparison not only reveals evolutionary relationships, but also sheds light on biological functional properties. However, traditional definitions of structure or sequence similarity always involve superposition or…

Quantitative Methods · Quantitative Biology 2017-07-13 Kelin Xia

We develop in this paper a theoretical framework for the topological study of time series data. Broadly speaking, we describe geometrical and topological properties of sliding window (or time-delay) embeddings, as seen through the lens of…

Algebraic Topology · Mathematics 2013-11-26 Jose Perea , John Harer

This paper develops the idea of homology for 1-parameter families of topological spaces. We express parametrized homology as a collection of real intervals with each corresponding to a homological feature supported over that interval or,…

Algebraic Topology · Mathematics 2019-03-20 Gunnar Carlsson , Vin de Silva , Sara Kalisnik , Dmitriy Morozov

Topological data analysis (TDA) aims to extract noise-robust features from a data set by examining the number and persistence of holes in its topology. We show that a computational problem closely related to a core task in TDA --…

Quantum Physics · Physics 2024-10-29 Casper Gyurik , Alexander Schmidhuber , Robbie King , Vedran Dunjko , Ryu Hayakawa