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We have recorded the swarming-like collective migration of a large number of keratocytes (tissue cells obtained from the scales of goldfish) using long-term videomicroscopy. By increasing the overall density of the migrating cells, we have…

Cell Behavior · Quantitative Biology 2009-11-13 Balint Szabo , Gergely J. Szollosi , Balazs Gonci , Zsofi Juranyi , David Selmeczi , Tamas Vicsek

Gastrulation, namely cell internalization, is a significant milestone during the development of metazoans from worm to human, which generates multiple embryonic layers with distinct cell fates and spatial organizations. Although many…

Cell Behavior · Quantitative Biology 2022-01-17 Jiao Miao , Guoye Guan , Chao Tang

Single photon source is one of the key devices for optical quantum information processing. Differing from the usual stimulated Raman adiabatic passage to obtain single-photon radiation, here we propose an approach to produce optical Fock…

Quantum Physics · Physics 2014-12-15 X. Shi , L. F. Wei

The self-organised motion of vast numbers of creatures in a single direction is a spectacular example of emergent order. We recreate this phenomenon using actuated non-living components. We report here that millimetre-sized tapered rods,…

Soft Condensed Matter · Physics 2014-09-23 Nitin Kumar , Harsh Soni , Sriram Ramaswamy , A. K. Sood

We investigate the nonequilibrium dynamics of active matter using a two-dimensional active Brownian particles model. In these systems, self-propelled particles undergo motility-induced phase separation (MIPS), spontaneously segregating into…

Soft Condensed Matter · Physics 2026-02-26 Toranosuke Umemura , Issei Sakai , Takuma Akimoto

Cell sorting, the segregation of cells with different properties into distinct domains, is a key phenomenon in biological processes such as embryogenesis. We use a phase-field model of a confluent cell layer to study the role of activity in…

Biological Physics · Physics 2024-03-05 James N. Graham , Guanming Zhang , Julia M. Yeomans

Using the classical tools of nonlinear dynamics, we study the process of self-organization and the appearance of the chaos in the metabolic process in a cell with the help of a mathematical model of the transformation of steroids by a cell…

Other Quantitative Biology · Quantitative Biology 2018-03-15 V. I. Grytsay , I. V. Musatenko

Concentrated suspensions of swimming microorganisms and other forms of active matter are known to display complex, self-organized spatio-temporal patterns on scales large compared to those of the individual motile units. Despite intensive…

Soft Condensed Matter · Physics 2014-07-15 Enkeleida Lushi , Hugo Wioland , Raymond E Goldstein

The process of programmed cell death, namely apoptosis, is a natural mechanism that regulates healthy tissue, multicellular structures, and homeostasis. An improved understanding of apoptosis can significantly enhance our knowledge of…

Cell Behavior · Quantitative Biology 2026-03-12 Daniel A. Vaughan , Anna M. Piccinini , Mischa Zelzer , Etienne Farcot , Bindi S. Brook , Kris Van-der-Zee , Luis Espath

Controlling the collective motion of epithelial cell populations is fundamental for understanding multicellular self-organization and for advancing tissue engineering. Under spatial confinement, cells are known to exhibit either vortex…

Soft Condensed Matter · Physics 2025-09-09 Ryo Ienaga , Kazuyuki Shigeta , Tatsuya Fukuyama , Kazusa Beppu , Yusuke T. Maeda

In this paper, we use the cell dynamics method to study the dynamics of phase transformation when three phases exist. The system we study is a two-dimensional system. The system is able to achieve three phases coexistence, which for…

Materials Science · Physics 2009-11-11 M. Iwamatsu

Aim. To study the dynamics of auto-oscillations arising at the level of enzyme-substrate interaction in a cell and to find the conditions for the self-organization and the formation of chaos in the metabolic process. Methods. A mathematical…

Adaptation and Self-Organizing Systems · Physics 2018-03-15 V. I. Grytsay , I. V. Musatenko

Biological mixtures such as the cytosol may consist of thousands of distinct components. There is now a substantial body of evidence showing that, under physiological conditions, intracellular mixtures can phase separate into spatially…

Soft Condensed Matter · Physics 2017-03-06 William M. Jacobs , Daan Frenkel

We introduce the notion of cell division-induced activity and show that the cell division generates extensile forces and drives dynamical patterns in cell assemblies. Extending the hydrodynamic models of lyotropic active nematics we…

Soft Condensed Matter · Physics 2015-08-07 Amin Doostmohammadi , Sumesh P. Thampi , Thuan B. Saw , Chwee T. Lim , Benoit Ladoux , Julia M. Yeomans

Cellular differentiation and evolution are stochastic processes that can involve multiple types (or states) of particles moving on a complex, high-dimensional state-space or "fitness" landscape. Cells of each specific type can thus be…

Populations and Evolution · Quantitative Biology 2014-11-17 Tom Chou , Yu Wang

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

Subcellular Processes · Quantitative Biology 2015-05-20 Pierre Sens , Matthew S. Turner

An important component in studying mathematical models in many biochemical systems, such as those found in developmental biology, is phase transition. The purpose of this work is to analyze the phase transition property of a…

Analysis of PDEs · Mathematics 2013-12-19 Masoud Yari

Finding suitable indicators for characterizing quantum phase transitions plays an important role in understanding different phases of matter. It is especially important for fracton phases where a combination of topology and…

Quantum Physics · Physics 2022-07-04 Mohammad Hossein Zarei , Mohammad Nobakht

Upon intense femtosecond photo-excitation, a many-body system can undergo a phase transition through a non-equilibrium route, but understanding these pathways remains an outstanding challenge. Here, we use time-resolved second harmonic…

During the morphogenesis of tissues and tumors, cells often interact with neighbors with different mechanical properties, but the understanding of its role is lacking. We use active Brownian Dynamics simulations to study a model co-culture…

Soft Condensed Matter · Physics 2021-01-07 Supravat Dey , Moumita Das