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An increase of static friction during stationary contacts of two solids due to interfacial chemical bonding has been reported in multiple experiments. However, the physics underlying such frictional aging is still not fully understood…

Soft Condensed Matter · Physics 2018-08-03 Zhuohan Li , Izabela Szlufarska

Aging changes including age spots and atherosclerotic plaques develop in an inhomogeneous and accelerated manner. For understanding this phenomenon, some aging changes are analyzed by Misrepair mechanism, a mechanism proposed in…

Other Quantitative Biology · Quantitative Biology 2018-02-07 Jicun Wang-Michelitsch , Thomas Michelitsch

Throughout the process of aging, deterioration of bone macro- and micro-architecture, as well as material decomposition result in a loss of strength and therefore in an increased likelihood of fractures. To date, precise contributions of…

Quantitative Methods · Quantitative Biology 2020-02-19 Pouyan Asgharzadeh , Oliver Röhrle , Bettina M. Willie , Annette I. Birkhold

Mineralized collagen microfibrils in human bone provide its mechanical properties (stiffness, elasticity, ductility, energy dissipation and strength). However, detailed 3D finite element models describing the mechanical behaviour of the…

Tissues and Organs · Quantitative Biology 2012-03-01 Ridha Hambli , Abdelwahed Barkaoui

Crosslinked polyurethane adhesives show large deformation viscoelastic behaviour and age under the moisture influence because of their hygroscopic behaviour. The viscoelastic behaviour of the material is modelled with the micromechanical…

Materials Science · Physics 2024-06-11 S. P. Josyula , M. Brede , O. Hesebeck , K. Koschek , W. Possart , A. Wulf , B. Zimmer , S. Diebels

We propose a three dimensional mechanical model of embryonic tissue dynamics. Mechanically coupled adherent cells are represented as particles interconnected with elastic beams which can exert non-central forces and torques. Tissue…

Biological Physics · Physics 2015-06-22 Andras Czirok , Dona Greta Isai

We develop theoretical equivalences between stochastic and deterministic models for populations of individual cells stratified by age. Specifically, we develop a hierarchical system of equations describing the full dynamics of an…

Populations and Evolution · Quantitative Biology 2022-06-29 Joshua C. Kynaston , Chris Guiver , Christian A. Yates

A new class of micromechanically motivated chain network models for soft biological tissues is presented. On the microlevel, it is based on the statistics of long chain molecules. A wormlike chain model is applied to capture the behavior of…

Quantitative Methods · Quantitative Biology 2009-11-10 E. Kuhl , K. Garikipati , E. M. Arruda , K. Grosh

The complex Ginzburg-Landau equation with additive noise is a stochastic partial differential equation that describes a remarkably wide range of physical systems which include coupled non-linear oscillators subject to external noise near a…

Statistical Mechanics · Physics 2020-01-27 Weigang Liu , Uwe C. Täuber

The skin microbiome plays an important role in the maintenance of a healthy skin. It is an ecosystem, composed of several species, competing for resources and interacting with the skin cells. Imbalance in the cutaneous microbiome, also…

Quantitative Methods · Quantitative Biology 2022-06-22 Eléa Thibault Greugny , Georgios N Stamatas , François Fages

This work presents a general unified theory for coupled nonlinear elastic and inelastic deformations of curved thin shells. The coupling is based on a multiplicative decomposition of the surface deformation gradient. The kinematics of this…

Classical Physics · Physics 2019-09-12 Roger A. Sauer , Reza Ghaffari , Anurag Gupta

Actin filaments, crosslinkers and myosin molecular motors form contractile networks. For instance, the cell cortex is a thin network below the cell membrane ; contraction of the cell cortex allows cells to round up during cell division.…

We develop a tensorial constitutive model for dense, shear-thickening particle suspensions subjected to time-dependent flow. Our model combines a recently proposed evolution equation for the suspension microstructure in rate-independent…

Soft solids with tunable mechanical response are at the core of new material technologies, but a crucial limit for applications is their progressive aging over time, which dramatically affects their functionalities. The generally accepted…

Soft Condensed Matter · Physics 2017-08-02 Mehdi Bouzid , Jader Colombo , Lucas Vieira Barbosa , Emanuela Del Gado

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set-point. This phenomenon is often referred to as mechanical homeostasis. In contradiction…

Computational Engineering, Finance, and Science · Computer Science 2021-09-23 Jonas F. Eichinger , Maximilian J. Grill , Iman Davoodi Kermani , Roland C. Aydin , Wolfgang A. Wall , Jay D. Humphrey , Christian J. Cyron

Skin contraction is an important biophysical process that takes place during and after the recovery of deep tissue injury. This process is mainly caused by fibroblasts (skin cells) and myofibroblasts (differentiated fibroblasts) that exert…

Numerical Analysis · Mathematics 2021-05-20 Q. Peng , F. J. Vermolen

We propose a two-scale model to resolve essential features of developmental tissue deformations. The model couples individual cellular behavior to the mechanics at tissue scale. This is realized by a multiphase-field model addressing the…

Soft Condensed Matter · Physics 2025-06-25 Lea Happel , Axel Voigt

A complete approach for the determination of the complex constitutive behaviour of textile composites through finite element simulation is presented in this paper. In this work, simulations of different loading cases are carried out on…

Soft Condensed Matter · Physics 2008-12-18 Damien Durville

Bone remodeling involves the coordinated removal of bone by osteoclasts and addition of bone by osteoblasts, a process that is modulated by the prevailing mechanical environment. In this paper a fully coupled model of bone remodeling is…

Tissues and Organs · Quantitative Biology 2012-08-02 Stefan Scheiner , Peter Pivonka , Christian Hellmich , David W. Smith

Statically indeterminate systems are experimentally demonstrated to be in fact dynamical at the microscopic scale. Take the classic ladder-wall problem, for instance. Depending on the Young's modulus of the wall, it may take up to twenty…

Soft Condensed Matter · Physics 2022-11-09 Jr-Jiun Lin , Chi-Chun Cheng , Yu-Chuan Cheng , Jih-Chiang Tsai , Tzay-Ming Hong