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Parameterizing mathematical models of biological systems often requires fitting to stable periodic data. In cardiac electrophysiology this typically requires converging to a stable action potential through long simulations. We explore this…

Quantitative Methods · Quantitative Biology 2025-01-16 Matt J Owen , Gary R Mirams

This paper proposes a model for combination of external and internal stimuli for the action selection in an autonomous agent, based in an action selection mechanism previously proposed by the authors. This combination model includes…

Artificial Intelligence · Computer Science 2007-05-23 Pedro Pablo Gonzalez Perez , Jose Negrete Martinez , Ariel Barreiro Garcia , Carlos Gershenson Garcia

This paper presents an improved version of the previously proposed self-consistent drift-diffusion-reaction model correcting for non-physical behavior at longer time scales. To this end a novel boundary condition is employed that takes into…

Materials Science · Physics 2020-06-19 Behrouz Raftari , Neil Budko , Kees Vuik

The application of existing methods for constructing optimal dynamic treatment regimes is limited to cases where investigators are interested in optimizing a utility function over a fixed period of time (finite horizon). In this manuscript,…

Methodology · Statistics 2015-10-22 Ashkan Ertefaie

A user can be represented as what he/she does along the history. A common way to deal with the user modeling problem is to manually extract all kinds of aggregated features over the heterogeneous behaviors, which may fail to fully represent…

Artificial Intelligence · Computer Science 2017-11-28 Chang Zhou , Jinze Bai , Junshuai Song , Xiaofei Liu , Zhengchao Zhao , Xiusi Chen , Jun Gao

In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a…

Analysis of PDEs · Mathematics 2025-02-11 Marcelo Bongarti , Christian Parkinson , Weinan Wang

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

Biological Physics · Physics 2022-11-22 Tiankai Zhao , Hongyan Yuan

Many chemical processes exhibit diverse timescale dynamics with a strong coupling between timescale sensitive variables. Model predictive control with a non-uniformly spaced optimisation horizon is an effective approach to multi-timescale…

Systems and Control · Electrical Eng. & Systems 2022-05-11 Ryan McCloy , Lai Wei , Jie Bao

The recently developed Life-Space-Foam approach to goal-directed human action deals with individual actor dynamics. This paper applies the model to characterize the dynamics of co-action by two or more actors. This dynamics is modelled by:…

Adaptation and Self-Organizing Systems · Physics 2009-07-01 Vladimir G. Ivancevic , Eugene V. Aidman , Leong Yen

On the basis of a quite realistic ionic Fenton--Karma model of the cardiac tissue we consider the problem of defibrillation by a local weak forcing. In contrast to other systems, this model accurately reproduces the most essential…

Chaotic Dynamics · Physics 2007-05-23 Ekaterina Zhuchkova , Boris Radnaev , Alexander Loskutov

The current work is motivated by the need for robust statistical methods for precision medicine; as such, we address the need for statistical methods that provide actionable inference for a single unit at any point in time. We aim to learn…

Statistics Theory · Mathematics 2021-07-02 Ivana Malenica , Aurelien Bibaut , Mark J. van der Laan

We introduce a theoretical framework for the rational approximation of optical response functions in resonant photonic systems. The framework is based on the AAA algorithm and further allows to solve the underlying nonlinear eigenproblems…

The well-established effective action and effective potential framework from the quantum field theory domain is adapted and successfully applied to classical field theories of the Doi and Peliti type for diffusion controlled reactions.…

Statistical Mechanics · Physics 2008-11-26 David Hochberg , M. -P. Zorzano

We model an overdamped Brownian particle that is subject to resetting facilitated by a ratchet potential on a spatially periodic domain. This asymmetric potential switches on with a constant rate, but switches off again only upon the…

Statistical Mechanics · Physics 2024-07-25 Connor Roberts , Emir Sezik , Eloise Lardet

We present an efficient spacetime optimization method to automatically generate animations for a general volumetric, elastically deformable body. Our approach can model the interactions between the body and the environment and automatically…

Graphics · Computer Science 2017-09-11 Zherong Pan , Dinesh Manocha

In this contribution we are concerned with efficient model reduction for multiscale problems arising in lithium-ion battery modeling with spatially resolved porous electrodes. We present new results on the application of the reduced basis…

Numerical Analysis · Mathematics 2019-10-30 Mario Ohlberger , Stephan Rave , Felix Schindler

We investigate the pushed-to-pulled transition for a minimal model for invasive fronts influence by ``aerotaxis,'' that is, when organisms follow oxygen gradients. We consider two singular reaction-advection-diffusion models for this. The…

Analysis of PDEs · Mathematics 2026-03-31 Mete Demircigil , Christopher Henderson

Inference-time controllable generation is essential for real-world applications of unconditional diffusion models. However, most existing techniques focus on individual samples, struggling in applications that require the sample population…

Machine Learning · Computer Science 2026-05-11 Hao Luan , See-Kiong Ng , Chun Kai Ling

In this paper we present the parameterization of a new interionic potential for stoichiometric, reduced and doped CeO$_2$. We use a dipole-polarizable potential (DIPPIM) and optimize its parameters by fitting them to a series of DFT…

Estimating treatment effects from observational data is of central interest across numerous application domains. Individual treatment effect offers the most granular measure of treatment effect on an individual level, and is the most useful…

Machine Learning · Statistics 2024-08-06 Hengrui Cai , Huaqing Jin , Lexin Li