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Randomness is an unavoidable feature of the intracellular environment due to chemical reactants being present in low copy number. That phenomenon, predicted by Delbr\"uck long ago \cite{delbruck40}, has been detected in both prokaryotic…

Molecular Networks · Quantitative Biology 2013-02-11 Alexandre F. Ramos , Jose Eduardo M. Hornos , John Reinitz

From the flashes of fireflies to Josephson junctions and power infrastructure, networks of coupled phase oscillators provide a powerful framework to describe synchronization phenomena in many natural and engineered systems. Most real-world…

Adaptation and Self-Organizing Systems · Physics 2022-03-02 Sherwood Martineau , Tim Saffold , Timothy T. Chang , Henrik Ronellenfitsch

A common assumption in evolutionary thought is that adaptation drives an increase in biological complexity. However, the rules governing evolution of complexity appear more nuanced. Evolution is deeply connected to learning, where…

Populations and Evolution · Quantitative Biology 2025-08-06 Hagai Rappeport , Mor Nitzan

Information maximization has been investigated as a possible mechanism of learning governing the self-organization that occurs within the neural systems of animals. Within the general context of models of neural systems bidirectionally…

Disordered Systems and Neural Networks · Physics 2015-11-18 Takashi Hayakawa , Toshio Aoyagi

Non-equilibrium random fluctuations of non-thermal nature are a salient feature of active matter. In this work, we consider the collective excitations of active systems at high density, focusing on a one-dimensional chain of elastically…

Soft Condensed Matter · Physics 2024-01-17 Umberto Marini Bettolo Marconi , Hartmut Löwen , Lorenzo Caprini

Nonlinear complex network-coupled systems typically have multiple stable equilibrium states. Following perturbations or due to ambient noise, the system is pushed away from its initial equilibrium and, depending on the direction and the…

Adaptation and Self-Organizing Systems · Physics 2023-06-08 Melvyn Tyloo

Noise is a ubiquitous feature of the physical world. As a result, the first prerequisite of life is fault tolerance: maintaining integrity of state despite external bombardment. Recent experimental advances have revealed that biological…

Populations and Evolution · Quantitative Biology 2023-04-14 Trevor McCourt , Ila R. Fiete , Isaac L. Chuang

Spatial patterning and synchronization are pervasive features of plankton communities, yet the mechanisms that allow such patterns to persist coherently under environmental noise remain unresolved. In vertically structured aquatic…

Pattern Formation and Solitons · Physics 2026-03-26 Ju Kang , Yiyuan Niu , Yuanzhi Li , Quan-Xing Liu , Chengjin Chu

Two mathematical models of macroevolution are studied. These models have population dynamics at the species level, and mutations and extinction of species are also included. The population dynamics are updated by difference equations with…

Populations and Evolution · Quantitative Biology 2014-04-16 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold

Noise-induced phase transitions are common in various complex systems, from physics to biology. In this article, we investigate the emergence of crucial events in noise-induced phase transition processes and their potential significance for…

Data Analysis, Statistics and Probability · Physics 2023-06-28 Jacob D. Baxley , David R. Lambert , Mauro Bologna , Bruce J. West , Paolo Grigolini

We perform a numerical investigation of the effect of the disorder associated with randomly located impurities on shot noise in mesoscopic cavities. We show that such a disorder becomes dominant in determining the noise behavior when the…

Mesoscale and Nanoscale Physics · Physics 2013-08-16 Paolo Marconcini , Massimo Totaro , Giovanni Basso , Massimo Macucci

Self-organized network dynamics prevails for systems across physics, biology and engineering. How external signals generate distributed responses in networked systems fundamentally underlies their function, yet is far from fully understood.…

Adaptation and Self-Organizing Systems · Physics 2019-08-05 Xiaozhu Zhang , Sarah Hallerberg , Moritz Matthiae , Dirk Witthaut , Marc Timme

An important characteristic of flocks of birds, school of fish, and many similar assemblies of self-propelled particles is the emergence of states of collective order in which the particles move in the same direction. When noise is added…

Statistical Mechanics · Physics 2015-01-19 M. Aldana , V. Dossetti , C. Huepe , V. M. Kenkre , H. Larralde

Coupling frequently enhances noise-induced coherence and synchronization in interacting nonlinear systems, but it does so separately. In principle collective stochastic coherence and synchronizability are incompatible phenomena, since…

Adaptation and Self-Organizing Systems · Physics 2015-06-17 Pablo Balenzuela , Pau Rué , Stefano Boccaletti , Jordi García-Ojalvo

We study the role of finiteness and fluctuations about average quantities for basic structural properties of growing networks. We first determine the exact degree distribution of finite networks by generating function approaches. The…

Statistical Mechanics · Physics 2009-11-07 P. L. Krapivsky , S. Redner

We study the interplay between diversity and noise in a 3D network of FitzHugh-Nagumo elements, with topology and dimensions chosen to model a pancreatic beta-cell cluster, as an example of an excitable cell network. Our results show that…

Biological Physics · Physics 2022-03-30 Stefano Scialla , Marco Patriarca , Els Heinsalu

We consider a generic class of gene circuits affected by nonlinear extrinsic noise. To address this nonlinearity we introduce a general perturbative methodology based on assuming timescale separation between noise and genes dynamics, with…

Molecular Networks · Quantitative Biology 2023-05-10 Gerardo Aquino , Andrea Rocco

Self-organization through noisy interactions is ubiquitous across physics, mathematics, and machine learning, yet how long-range structure emerges from local noisy dynamics remains poorly understood. Here, we investigate three paradigmatic…

Soft Condensed Matter · Physics 2026-03-31 Satyam Anand , Guanming Zhang , Stefano Martiniani

Phenotypic noise underpins homeostasis and fitness of individual cells. Yet, the extent to which noise shapes cell-to-population properties in microbial active matter remains poorly understood. By quantifying variability in confluent…

Biological Physics · Physics 2023-11-07 Jayabrata Dhar , Anh L. P. Thai , Arkajyoti Ghoshal , Luca Giomi , Anupam Sengupta

We study the effect of extrinsic noise in metabolic networks. We introduce external random fluctuations at the kinetic level, and show how these lead to a stochastic generalization of standard Metabolic Control Analysis. While Summation and…

Subcellular Processes · Quantitative Biology 2015-05-13 Andrea Rocco