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We study a character-based phylogeny reconstruction problem when an incomplete set of data is given. More specifically, we consider the situation under the directed perfect phylogeny assumption with binary characters in which for some…

Data Structures and Algorithms · Computer Science 2012-03-16 Masashi Kiyomi , Yoshio Okamoto , Toshiki Saitoh

The aim of this study is to investigate the relation that can be found between the phylogeny of a large set of complete chloroplast genomes, and the evolution of gene content inside these sequences. Core and pan genomes have been computed…

Genomics · Quantitative Biology 2016-09-21 Bashar Al-Nuaimi , Christophe Guyeux , Bassam AlKindy , Jean-François Couchot , Michel Salomon

Graph-structured data arise ubiquitously in many application domains. A fundamental problem is to quantify their similarities. Graph kernels are often used for this purpose, which decompose graphs into substructures and compare these…

Machine Learning · Computer Science 2020-03-26 Wei Ye , Zhen Wang , Rachel Redberg , Ambuj Singh

The Composition Vector Tree (CVTree) method, developed under the leadership of Professor Hao Bailin, is an alignment-free algorithm for constructing phylogenetic trees. Although initially designed for studying prokaryotic evolution based on…

Populations and Evolution · Quantitative Biology 2025-05-13 Yi-Fei Lu , Xiao-Yang Zhi , Guang-Hong Zuo

Old photos preserve invaluable historical memories, making their restoration and colorization highly desirable. While existing restoration models can address some degradation issues like denoising and scratch removal, they often struggle…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Bingchen Li , Zhixin Wang , Fan Li , Jiaqi Xu , Jiaming Guo , Renjing Pei , Xin Li , Zhibo Chen

In this article, we study directed graphs (digraphs) with a coloring constraint due to Von Neumann and related to Nim-type games. This is equivalent to the notion of kernels of digraphs, which appears in numerous fields of research such as…

Combinatorics · Mathematics 2012-02-06 Cyril Banderier , Jean-Marie Le Bars , Vlady Ravelomanana

Phylogenetic networks are a special type of graph which generalize phylogenetic trees and that are used to model non-treelike evolutionary processes such as recombination and hybridization. In this paper, we consider {\em unrooted}…

Combinatorics · Mathematics 2025-05-21 Katharina T. Huber , Simone Linz , Vincent Moulton

We present the first fixed-parameter algorithm for constructing a tree-child phylogenetic network that displays an arbitrary number of binary input trees and has the minimum number of reticulations among all such networks. The algorithm…

Discrete Mathematics · Computer Science 2019-07-22 Leo van Iersel , Remie Janssen , Mark Jones , Yukihiro Murakami , Norbert Zeh

Phylogenetic networks are necessary to represent the tree of life expanded by edges to represent events such as horizontal gene transfers, hybridizations or gene flow. Not all species follow the paradigm of vertical inheritance of their…

Populations and Evolution · Quantitative Biology 2016-02-15 Claudia Solís-Lemus , Cécile Ané

In Gaussian graphical model selection, noise-corrupted samples present significant challenges. It is known that even minimal amounts of noise can obscure the underlying structure, leading to fundamental identifiability issues. A recent line…

Machine Learning · Statistics 2024-05-09 Abrar Zahin , Rajasekhar Anguluri , Lalitha Sankar , Oliver Kosut , Gautam Dasarathy

In this paper, we introduce flubbles, a new definition of "bubbles" corresponding to variants in a (pan)genome graph $G$. We then show a characterization for flubbles in terms of equivalence classes regarding cycles in an intermediate data…

Data Structures and Algorithms · Computer Science 2024-10-29 Njagi Mwaniki , Erik Garrison , Nadia Pisanti

The supertree construction problem is about combining several phylogenetic trees with possibly conflicting information into a single tree that has all the leaves of the source trees as its leaves and the relationships between the leaves are…

Computational Engineering, Finance, and Science · Computer Science 2020-02-19 Laura Koponen , Emilia Oikarinen , Tomi Janhunen , Laura Säilä

We present practical algorithms for generating universal cycles uniformly at random. In particular, we consider universal cycles for shorthand permutations, subsets and multiset permutations, weak orders, and orientable sequences.…

Discrete Mathematics · Computer Science 2025-12-16 Joe Sawada , Daniel Gabrić

Massively parallel DNA sequencing technologies are revolutionizing genomics research. Billions of short reads generated at low costs can be assembled for reconstructing the whole genomes. Unfortunately, the large memory footprint of the…

Data Structures and Algorithms · Computer Science 2012-07-17 Yang Li , Pegah Kamousi , Fangqiu Han , Shengqi Yang , Xifeng Yan , Subhash Suri

When two-dimensional atomic crystals are brought into close proximity to form a van der Waals heterostructure, neighbouring crystals can start influencing each others electronic properties. Of particular interest is the situation when the…

We present a framework for the design of optimal assembly algorithms for shotgun sequencing under the criterion of complete reconstruction. We derive a lower bound on the read length and the coverage depth required for reconstruction in…

Genomics · Quantitative Biology 2013-02-20 Guy Bresler , Ma'ayan Bresler , David Tse

The main goal of Systems Biology research is to reconstruct biological networks for its topological analysis so that reconstructed networks can be used for the identification of various kinds of disease. The availability of high-throughput…

Systems and Control · Computer Science 2013-07-02 Khalid Raza , Rajni Jaiswal

The de Bruijn torus (or grid) problem looks to find an $n$-by-$m$ binary matrix in which every possible $j$-by-$k$ submatrix appears exactly once. The existence and construction of these binary matrices was determined in the 70's, with…

Combinatorics · Mathematics 2015-11-24 Victoria Horan , Brett Stevens

Decompilation aims to recover the source code form of a binary executable. It has many security applications, such as malware analysis, vulnerability detection, and code hardening. A prominent challenge in decompilation is to recover…

Software Engineering · Computer Science 2024-12-10 Xiangzhe Xu , Zhuo Zhang , Zian Su , Ziyang Huang , Shiwei Feng , Yapeng Ye , Nan Jiang , Danning Xie , Siyuan Cheng , Lin Tan , Xiangyu Zhang

In this paper, we study the parallel query complexity of reconstructing biological and digital phylogenetic trees from simple queries involving their nodes. This is motivated from computational biology, data protection, and computer…

Data Structures and Algorithms · Computer Science 2020-09-10 Ramtin Afshar , Michael T. Goodrich , Pedro Matias , Martha C. Osegueda