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Polymer translocation in crowded environments is a ubiquitous phenomenon in biological systems. We studied polymer translocation through a pore in free, one-sided (asymmetric), and two-sided (symmetric) crowded environments. Extensive…

Soft Condensed Matter · Physics 2024-03-01 Vrinda Garg , Rejoy Mathew , Riyan Ibrahim , Kulveer Singh , Surya K. Ghosh

Finite-size scaling arguments naturally lead us to introduce a coordinate-dependent diffusion coefficient in a Fokker-Planck description of the late stage dynamics of unbiased polymer translocation through a membrane pore. The solution for…

Statistical Mechanics · Physics 2015-06-17 Giovanni Brandani , Fulvio Baldovin , Enzo Orlandini , Attilio L. Stella

We study the model of a partially directed flexible or semi-flexible homopolymer on a square lattice, subject to an externally applied force, in a direction either parallel to, or perpendicular to the preferred direction. The polymer is…

Statistical Mechanics · Physics 2015-05-19 Pui-Man Lam , Yi Zhen

In recent years polymer translocation, i.e., transport of polymeric molecules through nanometer-sized pores and channels embedded in membranes, has witnessed strong advances. It is now possible to observe single-molecule polymer dynamics…

Soft Condensed Matter · Physics 2013-09-13 Debabrata Panja , Gerard T. Barkema , Anatoly B. Kolomeisky

By embedding inert tracer particles (TPs) in a growing multicellular spheroid the local stresses on the cancer cells (CCs) can be measured. In order for this technique to be effective the unknown effect of the dynamics of the TPs on the CCs…

Biological Physics · Physics 2020-10-20 Himadri S. Samanta , Sumit Sinha , D. Thirumalai

Two phase picture is a simple and effective methodology to capture the nonequilibrium dynamics of polymer associated with tension propagation. When applying it to the driven translocation process, there is a point to be noted, as briefly…

Soft Condensed Matter · Physics 2012-11-26 Takuya Saito , Takahiro Sakaue

When a flexible polymer is sucked into a localized small hole, the chain can initially respond only locally and the sequential nonequilibrium processes follow in line with the propagation of the tensile force along the chain backbone. We…

Soft Condensed Matter · Physics 2009-11-13 Takahiro Sakaue

Polymer translocation in three dimensions out of planar confinements is studied in this paper. Three membranes are located at $z=-h$, $z=0$ and $z=h_1$. These membranes are impenetrable, except for the middle one at $z=0$, which has a…

Soft Condensed Matter · Physics 2008-01-29 Debabrata Panja , Gerard T. Barkema , Robin C. Ball

We investigate the translocation dynamics of heteropolymers driven through a nanopore using a constant temperature Langevin thermostat. Specifically, we consider heteropolymers consisting of two types of monomers labeled A and B, which are…

Soft Condensed Matter · Physics 2007-05-23 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Aniket Bhattacharya

In this work a stochastic model of gaseous transfer in polymer/CNT nanocomposites is presented. The model takes into account interfacial areas, i.e. polymer depletion regions. The local regime of transport is controlled by the density of…

Materials Science · Physics 2023-11-09 Polina Kalashnikova , Ilia Kalashnikov , Konstantin Khromov

We develop a theoretical description of the topological disentanglement occurring when torus knots reach the ends of a semi-flexible polymer under tension. These include decays into simpler knots and total unknotting. The minimal number of…

Statistical Mechanics · Physics 2020-11-04 Michele Caraglio , Boris Marcone , Fulvio Baldovin , Enzo Orlandini , Attilio L. Stella

Chaperone-assisted translocation through a nanopore embedded in membrane holds a prominent role in the transport of biopolymers. Inspired by classical Brownian ratchet, we develop a theoretical framework characterizing such translocation…

Biological Physics · Physics 2020-02-17 Xining Xu , Yunxin Zhang

We study the passage (translocation) of a self-avoiding polymer through a membrane pore in two dimensions. In particular, we numerically measure the probability distribution Q(T) of the translocation time T, and the distribution P(s,t) of…

Statistical Mechanics · Physics 2009-02-12 Clément Chatelain , Yacov Kantor , Mehran Kardar

We explore the transport features of a single flexible polymer chain that walks on a periodic ratchet potential coupled with spatially varying temperature. At steady state the polymer exhibits a fast unidirectional motion where the…

Soft Condensed Matter · Physics 2015-07-20 Mesfin Asfaw Taye

Charge-carrier transport in a paradigmatic semicrystalline polymer semiconductor (P3HT) is important for both fundamental understanding and applications. In samples with enhanced structural disorder due to ad-hoc point defects, the mobility…

Soft Condensed Matter · Physics 2016-07-20 Breanndan O. Conchuir , Carlo Tarantini , Chris R. McNeill , Sven Hüttner , Alessio Zaccone

We study unbiased translocation of a flexible polymer chain through a membrane pore under the influence of active noise and steric exclusion using Langevin dynamics simulations. The active noise is incorporated by introducing nonchiral and…

Soft Condensed Matter · Physics 2022-07-19 Zahra Fazli , Ali Naji

We study the diffusion of a linear polymer in the presence of permeable membranes without excluded volume interactions, using scaling theory and Monte Carlo simulations. We find that the average time it takes for a chain with polymerization…

Condensed Matter · Physics 2016-08-31 Hyoungsoo Yoon , J. M. Deutsch

We investigate the phase behavior of athermal polymer/nanoparticle blends near a hard substrate. We apply the density functional theory of Tripathi and Chapman to these blends. We find a first order phase transition where the nanoparticles…

Soft Condensed Matter · Physics 2009-11-13 E. S. McGarrity , A. L. Frischknecht , L. J. D. Frink , M. E. Mackay

Polymer translocation through a nanometer-scale pore assisted by chaperones binding to the polymer is a process encountered in vivo for proteins. Studying the relevant models by computer simulations is computationally demanding.…

Biological Physics · Physics 2017-12-18 P. M. Suhonen , R. P. Linna

The purpose of this paper is to investigate several analytical methods of solving first passage (FP) problem for the Rouse model, a simplest model of a polymer chain. We show that this problem has to be treated as a multi-dimensional…

Soft Condensed Matter · Physics 2015-12-09 Jing Cao , Jian Zhu , Zuowei Wang , Alexei E. Likhtman