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Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from revealing the proteins' common origin. Moreover, when a large number of…

Quantitative Methods · Quantitative Biology 2011-01-18 Marta L. Gîrdea , Laurent Noé , Gregory Kucherov

The density estimation is one of the core problems in statistics. Despite this, existing techniques like maximum likelihood estimation are computationally inefficient due to the intractability of the normalizing constant. For this reason an…

Machine Learning · Computer Science 2021-01-14 Tsimboy Olga , Yermek Kapushev , Evgeny Burnaev , Ivan Oseledets

Feature subset selection, as a special case of the general subset selection problem, has been the topic of a considerable number of studies due to the growing importance of data-mining applications. In the feature subset selection problem…

Machine Learning · Computer Science 2014-11-13 Tofigh Naghibi , Sarah Hoffmann , Beat Pfister

Semantic clone detection is the process of finding program elements with similar or equal runtime behavior. For example, detecting the semantic equality between the recursive and iterative implementation of the factorial computation.…

Software Engineering · Computer Science 2022-05-24 Hannes Thaller , Lukas Linsbauer , Alexander Egyed

Image matching, which establishes correspondences between two-view images to recover 3D structure and camera geometry, serves as a cornerstone in computer vision and underpins a wide range of applications, including visual localization, 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Shihua Zhang , Zizhuo Li , Kaining Zhang , Yifan Lu , Yuxin Deng , Linfeng Tang , Xingyu Jiang , Jiayi Ma

Gradient-based dimension reduction decreases the cost of Bayesian inference and probabilistic modeling by identifying maximally informative (and informed) low-dimensional projections of the data and parameters, allowing high-dimensional…

Computation · Statistics 2025-06-02 Ricardo Baptista , Michael Brennan , Youssef Marzouk

Motivation. Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process, a design scoring function is critically…

Biomolecules · Quantitative Biology 2007-05-23 Changyu Hu , Xiang Li , Jie Liang

Differentiable rendering aims to compute the derivative of the image rendering function with respect to the rendering parameters. This paper presents a novel algorithm for 6-DoF pose estimation through gradient-based optimization using a…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Ramchander Rao Bhaskara , Roshan Thomas Eapen , Manoranjan Majji

Protein structure similarity search (PSSS), which tries to search proteins with similar structures, plays a crucial role across diverse domains from drug design to protein function prediction and molecular evolution. Traditional…

Machine Learning · Computer Science 2024-11-14 Jin Han , Wu-Jun Li

Graph matching is a fundamental tool in computer vision and pattern recognition. In this paper, we introduce an algorithm for graph matching based on the proximal operator, referred to as differentiable proximal graph matching (DPGM).…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Haoru Tan , Chuang Wang , Xu-Yao Zhang , Cheng-Lin Liu

Non-negative matrix factorization (NMF) is a key technique for feature extraction and widely used in source separation. However, existing algorithms may converge to poor local minima, or to one of several minima with similar objective value…

Machine Learning · Computer Science 2024-10-30 Youdong Guo , Timothy E. Holy

Existing supervised action segmentation methods depend on the quality of frame-wise classification using attention mechanisms or temporal convolutions to capture temporal dependencies. Even boundary detection-based methods primarily depend…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Kamel Aouaidjia , Wenhao Zhang , Aofan Li , Chongsheng Zhang

Protein tertiary structure defines its functions, classification and binding sites. Similar structural characteristics between two proteins often lead to the similar characteristics thereof. Determining structural similarity accurately in…

Computer Vision and Pattern Recognition · Computer Science 2016-10-05 Rezaul Karim , Md. Momin Al Aziz , Swakkhar Shatabda , M. Sohel Rahman

Feature matching between image pairs is a fundamental problem in computer vision that drives many applications, such as SLAM. Recently, semi-dense matching approaches have achieved substantial performance enhancements and established a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Xiaolong Wang , Lei Yu , Yingying Zhang , Jiangwei Lao , Lixiang Ru , Liheng Zhong , Jingdong Chen , Yu Zhang , Ming Yang

We propose a novel method of deep spatial matching (DSM) for image retrieval. Initial ranking is based on image descriptors extracted from convolutional neural network activations by global pooling, as in recent state-of-the-art work.…

Computer Vision and Pattern Recognition · Computer Science 2019-11-19 Oriane Siméoni , Yannis Avrithis , Ondrej Chum

Image alignment tasks require accurate pixel correspondences, which are usually recovered by matching local feature descriptors. Such descriptors are often derived using supervised learning on existing datasets with ground truth…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Jing Dong , Byron Boots , Frank Dellaert , Ranveer Chandra , Sudipta N. Sinha

Stochastic gradient descent algorithms for training linear and kernel predictors are gaining more and more importance, thanks to their scalability. While various methods have been proposed to speed up their convergence, the model selection…

Machine Learning · Computer Science 2014-06-17 Francesco Orabona

In general, deep neural network (DNN) pruning methods fall into two categories: 1) Weight-based deterministic constraints, and 2) Probabilistic frameworks. While each approach has its merits and limitations there are a set of common…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Madan Ravi Ganesh , Dawsin Blanchard , Jason J. Corso , Salimeh Yasaei Sekeh

Probabilistic inference in pairwise Markov Random Fields (MRFs), i.e. computing the partition function or computing a MAP estimate of the variables, is a foundational problem in probabilistic graphical models. Semidefinite programming…

Machine Learning · Computer Science 2021-05-04 Chirag Pabbaraju , Po-Wei Wang , J. Zico Kolter

Sampling and quantization are standard practices in signal and image processing, but a theoretical understanding of their impact is incomplete. We consider discrete image registration when the underlying function is a one-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Serap A. Savari