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Accurately assigning folds for divergent protein sequences is a major obstacle to structural studies and underlies the inverse protein folding problem. Herein, we outline our theories for fold-recognition in the "twilight-zone" of sequence…

Quantitative Methods · Quantitative Biology 2010-08-31 Yoojin Hong , Kyung Dae Ko , Gaurav Bhardwaj , Zhenhai Zhang , Damian B. van Rossum , Randen L. Patterson

Stochastic coordinate descent algorithms are efficient methods in which each iterate is obtained by fixing most coordinates at their values from the current iteration, and approximately minimizing the objective with respect to the remaining…

Machine Learning · Statistics 2025-04-02 Eméric Gbaguidi

Learning synaptic weights of spiking neural network (SNN) models that can reproduce target spike trains from provided neural firing data is a central problem in computational neuroscience and spike-based computing. The discovery of the…

Neural and Evolutionary Computing · Computer Science 2019-10-10 Bryce Bagley , Blake Bordelon , Benjamin Moseley , Ralf Wessel

Modern deep neural network (DNN) training jobs use complex and heterogeneous software/hardware stacks. The efficacy of software-level optimizations can vary significantly when used in different deployment configurations. It is onerous and…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-08 Hongyu Zhu , Amar Phanishayee , Gennady Pekhimenko

Recently, the joint design of optical systems and downstream algorithms is showing significant potential. However, existing rays-described methods are limited to optimizing geometric degradation, making it difficult to fully represent the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Zheng Ren , Jingwen Zhou , Wenguan Zhang , Jiapu Yan , Bingkun Chen , Huajun Feng , Shiqi Chen

In object segmentation by active contours, the initial contour is often required. Conventionally, the initial contour is provided by the user. This paper extends the conventional active contour model by incorporating feature matching in the…

Computer Vision and Pattern Recognition · Computer Science 2013-07-25 Junyan Wang , Kap Luk Chan

Learning to autonomously assemble shapes is a crucial skill for many robotic applications. While the majority of existing part assembly methods focus on correctly posing semantic parts to recreate a whole object, we interpret assembly more…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Yun-Chun Chen , Haoda Li , Dylan Turpin , Alec Jacobson , Animesh Garg

Feature matching and finding correspondences between endoscopic images is a key step in many clinical applications such as patient follow-up and generation of panoramic image from clinical sequences for fast anomalies localization.…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Manel Farhat , Houda Chaabouni-Chouayakh , Achraf Ben-Hamadou

Convolutional neural networks (CNNs) are one of the most effective deep learning methods to solve image classification problems, but the best architecture of a CNN to solve a specific problem can be extremely complicated and hard to design.…

Neural and Evolutionary Computing · Computer Science 2018-03-20 Bin Wang , Yanan Sun , Bing Xue , Mengjie Zhang

Novel view synthesis (NVS) approaches such as NeRFs or 3DGS can produce photo-realistic 3D scene representation from a set of images with known extrinsic and intrinsic parameters. The necessary camera poses and calibrations are typically…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jhacson Meza , Martin R. Oswald , Torsten Sattler

We develop a data-driven machine learning approach to identifying parameters with steady-state solutions, locating such solutions, and determining their linear stability for systems of ordinary differential equations and dynamical systems…

Numerical Analysis · Mathematics 2025-03-11 Yimeng Zhang , Alexander Cloninger , Bo Li , Xiaochuan Tian

Automatic matching of job offers and job candidates is a major problem for a number of organizations and job applicants that if it were successfully addressed could have a positive impact in many countries around the world. In this context,…

Other Computer Science · Computer Science 2023-05-08 Jorge Martinez-Gil , Alejandra Lorena Paoletti , Mario Pichler

Audio signal processing algorithms are frequently assessed through subjective listening tests in which participants directly score degraded signals on a unidimensional numerical scale. However, this approach is susceptible to…

Audio and Speech Processing · Electrical Eng. & Systems 2025-08-26 Jack Webb , Lorenzo Picinali

Score matching provides an effective approach to learning flexible unnormalized models, but its scalability is limited by the need to evaluate a second-order derivative. In this paper, we present a scalable approximation to a general family…

Machine Learning · Statistics 2020-02-19 Ziyu Wang , Shuyu Cheng , Yueru Li , Jun Zhu , Bo Zhang

Many existing conditional score-based data generation methods utilize Bayes' theorem to decompose the gradients of a log posterior density into a mixture of scores. These methods facilitate the training procedure of conditional score…

Machine Learning · Computer Science 2022-03-29 Chen-Hao Chao , Wei-Fang Sun , Bo-Wun Cheng , Yi-Chen Lo , Chia-Che Chang , Yu-Lun Liu , Yu-Lin Chang , Chia-Ping Chen , Chun-Yi Lee

Subjective image quality assessment studies are used in many scenarios, such as the evaluation of compression, super-resolution, and denoising solutions. Among the available subjective test methodologies, pair comparison is attracting…

Multimedia · Computer Science 2024-03-19 Shima Mohammadi , João Ascenso

We present a new algorithm for solving optimization problems with objective functions that are the sum of a smooth function and a (potentially) nonsmooth regularization function, and nonlinear equality constraints. The algorithm may be…

Optimization and Control · Mathematics 2024-04-12 Yutong Dai , Xiaoyi Qu , Daniel P. Robinson

High dimensional sparse learning has imposed a great computational challenge to large scale data analysis. In this paper, we are interested in a broad class of sparse learning approaches formulated as linear programs parametrized by a {\em…

Machine Learning · Computer Science 2017-11-28 Haotian Pang , Robert Vanderbei , Han Liu , Tuo Zhao

Schema matching is the process of identifying correspondences between the elements of two given schemata, essential for database management systems, data integration, and data warehousing. For datasets across different scenarios, the…

Databases · Computer Science 2025-03-07 Longyu Feng , Huahang Li , Chen Jason Zhang

Task learning in neural networks typically requires finding a globally optimal minimizer to a loss function objective. Conventional designs of swarm based optimization methods apply a fixed update rule, with possibly an adaptive step-size…

Machine Learning · Computer Science 2022-11-29 Chandrajit Bajaj , Omatharv Bharat Vaidya , Yi Wang
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