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Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Biomolecules · Quantitative Biology 2021-01-26 Stephan Eismann , Raphael J. L. Townshend , Nathaniel Thomas , Milind Jagota , Bowen Jing , Ron O. Dror

A novel code for the approximate computation of long-range forces between N mutually interacting bodies is presented. The code is based on a hierarchical tree of cubic cells and features mutual cell-cell interactions which are calculated…

Astrophysics · Physics 2009-11-07 Walter Dehnen

Numerical quantum transport calculations are commonly based on a tight-binding formulation. A wide class of quantum transport algorithms requires the tight-binding Hamiltonian to be in the form of a block-tridiagonal matrix. Here, we…

Mesoscale and Nanoscale Physics · Physics 2010-10-05 Michael Wimmer , Klaus Richter

Representation learning has become an invaluable approach for learning from symbolic data such as text and graphs. However, while complex symbolic datasets often exhibit a latent hierarchical structure, state-of-the-art methods typically…

Artificial Intelligence · Computer Science 2017-05-29 Maximilian Nickel , Douwe Kiela

Matrix multiplication (MatMul) is the computational backbone of modern machine learning, yet its classical complexity remains a bottleneck for large-scale data processing. We propose a hybrid quantum-classical algorithm for matrix…

Quantum Physics · Physics 2026-04-15 Wladimir Silva

In this work we develop several new simulation algorithms for 1D many-body quantum mechanical systems combining the Matrix Product State variational ansatz with Taylor, Pade and Arnoldi approximations to the evolution operator. By comparing…

Strongly Correlated Electrons · Physics 2007-05-23 Juan Jose Garcia-Ripoll

We consider the Online Boolean Matrix-Vector Multiplication (OMV) problem studied by Henzinger et al. [STOC'15]: given an $n \times n$ Boolean matrix $M$, we receive $n$ Boolean vectors $v_1,\ldots,v_n$ one at a time, and are required to…

Data Structures and Algorithms · Computer Science 2016-05-09 Kasper Green Larsen , Ryan Williams

Spectral methods are widely used in geometry processing of 3D models. They rely on the projection of the mesh geometry on the basis defined by the eigenvectors of the graph Laplacian operator, becoming computationally prohibitive as the…

Signal Processing · Electrical Eng. & Systems 2018-10-08 Gerasimos Arvanitis , Aris S. Lalos , Konstantinos Moustakas

Accurate models of robot dynamics are critical for safe and stable control and generalization to novel operational conditions. Hand-designed models, however, may be insufficiently accurate, even after careful parameter tuning. This…

Robotics · Computer Science 2021-11-29 Thai Duong , Nikolay Atanasov

In this paper, a hierarchical Tucker low-rank (HTLR) matrix is proposed to approximate non-oscillatory kernel functions in linear complexity. The HTLR matrix is based on the hierarchical matrix, with the low-rank blocks replaced by Tucker…

Numerical Analysis · Mathematics 2025-08-11 Yingzhou Li , Jingyu Liu

Employing techniques from scattering amplitudes and effective field theory, we model the dynamics of hierarchical triples, which are three-body systems composed of two bodies separated by a distance $r$ and a third body a distance $\rho$…

High Energy Physics - Theory · Physics 2025-02-07 Mikhail P. Solon , Anna M. Wolz

We present an explicit quantum circuit construction for Hamiltonian simulation of a first-order velocity--stress formulation of the three-dimensional elastic wave equation in homogeneous isotropic media. Previous studies have shown how…

Quantum Physics · Physics 2026-04-23 Kosuke Nakanishi , Hiroshi Yano , Yuki Sato

Efficient solution of 3D elasticity problems is an important part of many industrial and scientific applications. Smoothed aggregation algebraic multigrid using rigid body modes for the tentative prolongation operator construction is an…

Mathematical Software · Computer Science 2022-02-21 Denis Demidov

Elastic filaments are vital to biological, physical and engineering systems, from cilia driving fluid in the lungs to artificial swimmers and micro-robotics. Simulating slender structures requires intricate balance of elastic, body, active,…

Biological Physics · Physics 2023-06-02 Paul Fuchter , Hermes Bloomfield-Gadêlha

The Kinesin family of motor proteins are involved in a variety of cellular processes that transport materials and generate force. With recent advances in experimental techniques, such as optical tweezers which can probe individual…

Soft Condensed Matter · Physics 2023-02-28 P. J. Atzberger , C. S. Peskin

This paper addresses the problem of efficiently computing higher-order variational integrators in simulation and trajectory optimization of mechanical systems as those often found in robotic applications. We develop $O(n)$ algorithms to…

Robotics · Computer Science 2019-04-30 Taosha Fan , Jarvis Schultz , Todd Murphey

An overview of the mathematical structure of the three-dimensional (3D) Ising model is given, from the viewpoints of topologic, algebraic and geometric aspects. By analyzing the relations among transfer matrices of the 3D Ising model,…

General Physics · Physics 2013-05-15 Zhi-dong Zhang

We study the two-dimensional hierarchical rectangle packing problem, motivated by applications in analog integrated circuit layout, facility layout, and logistics. Unlike classical strip or bin packing, the dimensions of the container are…

Computational Geometry · Computer Science 2025-12-24 Josef Grus , Zdeněk Hanzálek , Christian Artigues , Cyrille Briand , Emmanuel Hebrard

In this report, we explore the use of a quantum optimization algorithm for obtaining low energy conformations of protein models. We discuss mappings between protein models and optimization variables, which are in turn mapped to a system of…

Quantum algorithms have been developed for efficiently solving linear algebra tasks. However, they generally require deep circuits and hence universal fault-tolerant quantum computers. In this work, we propose variational algorithms for…

Quantum Physics · Physics 2021-12-28 Xiaosi Xu , Jinzhao Sun , Suguru Endo , Ying Li , Simon C. Benjamin , Xiao Yuan