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The conformations and dynamics of semiflexible filaments subject to a homogeneous external (gravitational) field, e.g., in a centrifuge, are studied numerically and analytically. The competition between hydrodynamic drag and bending…

Biological Physics · Physics 2016-08-23 G. Saggiorato , J. Elgeti , R. G. Winkler , G. Gompper

Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the action of internal molecular motors and are typically found in dense arrays. These active filaments coordinate their beating to generate…

Soft Condensed Matter · Physics 2022-01-28 Brato Chakrabarti , Sebastian Fürthauer , Michael J. Shelley

Synchronization plays a crucial role in the dynamics of living organisms, from fireflies flashing in unison to pacemaker cells that jointly generate heartbeats. Uncovering the mechanism behind these phenomena requires an understanding of…

Adaptation and Self-Organizing Systems · Physics 2024-05-16 Aleksandre Japaridze , Victor Struijk , Kushal Swamy , Irek Roslon , Oriel Shoshani , Cees Dekker , Farbod Alijani

We study the over-damped dynamics of individual one-dimensional elastic filaments subjected to a chiral active force which propels each point of the filament at a fixed angle relative to the tangent vector of the filament at that point.…

Soft Condensed Matter · Physics 2026-03-09 Chanania Steinbock , Daniel A. Beller

A living cell actively generates traction forces on its environment with its actin cytoskeleton. These forces deform the cell elastic substrate which, in turn, affects the traction forces exerted by the cell and can consequently modify the…

Biological Physics · Physics 2022-02-03 H. Chelly , A. Jahangiri , M. Mireux , J. Étienne , D. K. Dysthe , C. Verdier , P. Recho

Active matter systems evade the constraints of thermal equilibrium, leading to the emergence of intriguing collective behavior. A paradigmatic example is given by motor-filament mixtures, where the motion of motor proteins drives alignment…

Soft Condensed Matter · Physics 2024-09-11 Filippo De Luca , Ivan Maryshev , Erwin Frey

Fluid-structure interactions between active and passive components are important for many biological systems to function. A particular example is chromatin in the cell nucleus, where ATP-powered processes drive coherent motions of the…

Soft Condensed Matter · Physics 2024-02-15 Scott Weady , David B. Stein , Alexandra Zidovska , Michael J. Shelley

Asymmetries and anisotropies are widespread in biological systems, including in the structure and dynamics of cilia and eukaryotic flagella. These microscopic, hair-like appendages exhibit asymmetric beating patterns that break…

Soft Condensed Matter · Physics 2025-08-22 Bethany Clarke , Yongyun Hwang , Eric E Keaveny

Systems with two species of active molecular motors moving on (cytoskeletal) filaments into opposite directions are studied theoretically using driven lattice gas models. The motors can unbind from and rebind to the filaments. Two motors…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

Many biological microorganisms and artificial microswimmers react to external cues of environmental gradients by changing their swimming directions. We study here the behavior of eukarytic flagellated microswimmers in linear viscosity…

Soft Condensed Matter · Physics 2026-05-29 Shubham Anand , Jens Elgeti , Gerhard Gompper

We study phase separation between coexisting active and passive fluids in three-dimensions, using numerical simulation and experiments. Chaotic flows of the active phase drive giant interfacial deformations, causing the co-existing phases…

Soft Condensed Matter · Physics 2026-02-16 Paarth Gulati , Liang Zhao , Michio Tateno , Omar A. Saleh , Zvonimir Dogic , M. Cristina Marchetti

The interplay between cytoskeletal architecture and the nonlinearity of the interactions due to bucklable filaments plays a key role in modulating the cell's mechanical stability and affecting its structural rearrangements. We study a model…

Statistical Mechanics · Physics 2011-07-01 Shenshen Wang , Tongye Shen , Peter G. Wolynes

Flagella and cilia are cellular appendages that inherit essential functions of microbial life including sensing and navigating the environment. In order to propel a swimming microorganism they displace the surrounding fluid by means of…

Dynamic organization of the cytoskeletal filaments and rod-like proteins in the cell membrane and other biological interfaces occurs in many cellular processes. Previous modeling studies have considered the dynamics of a single rod on fluid…

Fluid Dynamics · Physics 2022-06-17 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

Biological systems are robust to perturbations at both the genetic and environmental levels. Yet, these same perturbations can elicit variation in behavior. The interplay between functional robustness and behavioral variability is…

Biological Physics · Physics 2021-06-03 Veikko Geyer , Jonathon Howard , Pablo Sartori

Fiberboids are active filaments trapped at the interface of two phases, able of harnessing energy (and matter) fluxes across the interface in order to produce a rolling-like self-propulsion. We discuss several table-top examples and develop…

Soft Condensed Matter · Physics 2020-05-19 Antony Bazir , Arthur Baumann , Falko Ziebert , Igor M. Kulic

Peritrichous bacteria swim in viscous fluids by rotating multiple helical flagellar filaments. As the bacterium swims forward, all its flagella rotate in synchrony behind the cell in a helical bundle. When the bacterium changes its…

Fluid Dynamics · Physics 2017-11-16 Yi Man , William Page , Robert J. Poole , Eric Lauga

Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling…

Fluid Dynamics · Physics 2018-06-13 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

The deformations of flagella are important in the motility of single- and multi-flagellated bacteria. Existing numerical methods have treated flagella as extensible filaments with a large extensional modulus, resulting in a stiff numerical…

Fluid Dynamics · Physics 2020-07-15 Mehdi Jabbarzadeh , Henry C. Fu

Buckling plays a critical role in the transport and dynamics of elastic microfilaments in Stokesian fluids. However, previous work has only considered filaments with homogeneous structural properties. Filament backbone stiffness can be…

Soft Condensed Matter · Physics 2023-01-20 Thomas Nguyen , Harishankar Manikantan