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Hypergraphs model higher-order relations that drive real-world decisions, from drug prescriptions to recommendations. A central structural signal in such data, beyond what pairwise relations can express, is interaction compositionality:…

Machine Learning · Computer Science 2026-05-19 Kyrie Zhao , Zehong Wang , Tianyi Ma , Fang Wu , Xiangru Tang , Pietro Lio , Sheng Wang , Yanfang Ye

To improve the classification performance and generalization ability of the hyperspectral image classification algorithm, this paper uses Multi-Scale Total Variation (MSTV) to extract the spectral features, local binary pattern (LBP) to…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Zhixin Yan , Jiawei Huang , Kehua Xiang

Kernel methods approximate nonlinear maps in a data-driven manner by projecting the target map onto a finite-dimensional Hilbert space called the solution space. Traditionally, this space is a subspace of a fixed ambient reproducing kernel…

Numerical Analysis · Mathematics 2026-01-30 Tamás Dózsa , Andrea Angino , Zoltán Szabó , József Bokor , Matthias Voigt

Traditionally, spline or kernel approaches in combination with parametric estimation are used to infer the linear coefficient (fixed effects) in a partially linear mixed-effects model for repeated measurements. Using machine learning…

Methodology · Statistics 2023-04-03 Corinne Emmenegger , Peter Bühlmann

When devising a course of treatment for a patient, doctors often have little quantitative evidence on which to base their decisions, beyond their medical education and published clinical trials. Stanford Health Care alone has millions of…

A critical task in systems biology is the identification of genes that interact to control cellular processes by transcriptional activation of a set of target genes. Many methods have been developed to use statistical correlations in…

Quantitative Methods · Quantitative Biology 2010-11-24 Adam A. Margolin , Kai Wang , Andrea Califano , Ilya Nemenman

The reliability of a high-throughput biological experiment relies highly on the settings of the operational factors in its experimental and data-analytic procedures. Understanding how operational factors influence the reproducibility of the…

Methodology · Statistics 2018-07-04 Feipeng Zhang , Frank Shen , Tao Yang , Qunhua Li

The wide variety of brain imaging technologies allows us to exploit information inherent to different data modalities. The richness of multimodal datasets may increase predictive power and reveal latent variables that otherwise would have…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Alvaro Ulloa , Sergey Plis , Vince Calhoun

Describing the collective activity of neural populations is a daunting task: the number of possible patterns grows exponentially with the number of cells, resulting in practically unlimited complexity. Recent empirical studies, however,…

Neurons and Cognition · Quantitative Biology 2012-02-02 Andrea K. Barreiro , Julijana Gjorgjieva , Fred Rieke , Eric Shea-Brown

We propose Causal Interaction Trees for identifying subgroups of participants that have enhanced treatment effects using observational data. We extend the Classification and Regression Tree algorithm by using splitting criteria that focus…

Methodology · Statistics 2021-12-08 Jiabei Yang , Issa J. Dahabreh , Jon A. Steingrimsson

The problem of controlling higher-order interactions in neural networks is addressed with techniques commonly applied in the cluster analysis of quantum many-particle systems. For multi-neuron synaptic weights chosen according to a…

Disordered Systems and Neural Networks · Physics 2007-05-23 K. E. Kurten , J. W. Clark

Superpixels are higher-order perceptual groups of pixels in an image, often carrying much more information than the raw pixels. There is an inherent relational structure to the relationship among different superpixels of an image such as…

Computer Vision and Pattern Recognition · Computer Science 2022-05-23 Gunjan Chhablani , Abheesht Sharma , Harshit Pandey , Tirtharaj Dash

The functional characterization of different neuronal types has been a longstanding and crucial challenge. With the advent of physical quantum computers, it has become possible to apply quantum machine learning algorithms to translate…

Quantum Physics · Physics 2025-02-11 Xavier Vasques , Hanhee Paik , Laura Cif

To understand collective network behavior in the complex human brain, pairwise correlation networks alone are insufficient for capturing the high-order interactions that extend beyond pairwise interactions and play a crucial role in brain…

Neurons and Cognition · Quantitative Biology 2025-07-01 Qiang Li , Jingyu Liu , Vince D. Calhoun

Motivation: Histone modifications are among the most important factors that control gene regulation. Computational methods that predict gene expression from histone modification signals are highly desirable for understanding their…

Machine Learning · Computer Science 2016-07-08 Ritambhara Singh , Jack Lanchantin , Gabriel Robins , Yanjun Qi

Quantum kernel methods have emerged as a promising approach for leveraging high-dimensional feature spaces in machine learning, particularly in domains where classical kernel methods face scalability limitations. In this work, we present…

Quantum Physics · Physics 2026-05-19 A. Delilbasic , A. Miroszewski , A. Wijata , J. Nalepa , J. Mielczarek , M. Riedel , G. Cavallaro

The mining and utilization of features directly affect the classification performance of models used in the classification and recognition of hyperspectral remote sensing images. Traditional models usually conduct feature mining from a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Yunsong Zhao , Yin Li , Zhihan Chen , Tianchong Qiu , Guojin Liu

Associating genetic markers with a multidimensional phenotype is an important yet challenging problem. In this work, we establish the equivalence between two popular methods: kernel-machine regression (KMR), and kernel distance covariance…

Machine Learning · Statistics 2014-04-03 Wen-Yu Hua , Debashis Ghosh

Multiple kernel learning (MKL) aims to find an optimal, consistent kernel function. In the hierarchical multiple kernel clustering (HMKC) algorithm, sample features are extracted layer by layer from a high-dimensional space to maximize the…

Machine Learning · Computer Science 2024-10-29 Lei Wang , Liang Du , Peng Zhou

Methods to effectively detect multi-locus genetic association are becoming increasingly relevant in the genetic dissection of complex trait in humans. Current approaches typically consider a limited number of hypotheses, most of which are…

Genomics · Quantitative Biology 2007-05-23 Zhong Li , Aris Floratos , David Wang , Andrea Califano