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The large-time asymptotics of weak solutions to Maxwell--Stefan diffusion systems for chemically reacting fluids with different molar masses and reversible reactions are investigated. The diffusion matrix of the system is generally neither…

Analysis of PDEs · Mathematics 2019-07-29 Esther S. Daus , Ansgar Jüngel , Bao Quoc Tang

In this paper we perform a formal asymptotic analysis on a kinetic model for reactive mixtures in order to derive a reaction-diffusion system of Maxwell-Stefan type. More specifically, we start from the kinetic model of simple reacting…

Fluid Dynamics · Physics 2019-11-20 Benjamin Anwasia , Patrícia Gonçalves , Ana Jacinta Soares

We study the long-time behavior of the solutions of a two-component reaction-diffusion system on the real line, which describes the basic chemical reaction $A <=> 2 B$. Assuming that the initial densities of the species $A, B$ are bounded…

Analysis of PDEs · Mathematics 2021-06-30 Thierry Gallay , Sinisa Slijepcevic

Chemical reaction network theory is a powerful framework to describe and analyze chemical systems. While much about the concentration profile in an equilibrium state can be determined in terms of the graph structure, the overall reaction's…

Molecular Networks · Quantitative Biology 2024-02-29 Tomoharu Suda

Enzyme kinetics is very often characterised by the irreversible Michaelis-Menten (MM) equation. However, in open chemical reaction networks such as metabolic pathways, this approach can lead to significant kinetic and thermodynamic…

Biological Physics · Physics 2020-06-12 Valérie Voorsluijs , Francesco Avanzini , Massimiliano Esposito

We recall the perturbation expansion for Michaelis-Menten kinetics, beyond the standard quasi-steady-state approximation (sQSSA). Against this background, we are able to appropriately apply the alternative approach to the study of…

Chemical Physics · Physics 2016-11-16 Barbara Coluzzi , Alberto Maria Bersani , Enrico Bersani

Moment approximation methods are gaining increasing attention for their use in the approximation of the stochastic kinetics of chemical reaction systems. In this paper we derive a general moment expansion method for any type of propensities…

Molecular Networks · Quantitative Biology 2015-06-15 Angelique Ale , Paul Kirk , Michael P. P. Stumpf

In this paper, we consider concentration phenomenon of semiclassical states to the following $2M$-component reaction-diffusion system in $\R \times \R^N$, \begin{align*} \left\{ \begin{aligned} \partial_t u &=\eps^2 \Delta_x u-u-V(x)v +…

Analysis of PDEs · Mathematics 2022-12-29 Tianxiang Gou , Zhitao Zhang

There are many mathematical models of biochemical cell signaling pathways that contain a large number of elements (species and reactions). This is sometimes a big issue for identifying critical model elements and describing the model…

Molecular Networks · Quantitative Biology 2021-09-15 Hemn Mohammed Rasool , Sarbaz H. A. Khoshnaw

We consider a spatially extended mesoscopic FitzHugh-Nagumo model with strong local interactions and prove that its asymptotic limit converges towards the classical nonlocal reaction-diffusion FitzHugh-Nagumo system. As the local…

Analysis of PDEs · Mathematics 2022-08-31 Alain Blaustein , Francis Filbet

Understanding the asymptotic behavior of reaction-diffusion (RD) systems is crucial for modeling processes ranging from species coexistence in ecology to biochemical interactions within cells. In this work, we analyze RD systems in which…

Dynamical Systems · Mathematics 2025-02-18 Carlos Barajas , Jean-Jacques Slotine , Domitilla Del Vecchio

In this work, we revisit the scaling analysis and commonly accepted conditions for the validity of the standard, reverse and total quasi-steady-state approximations through the lens of dimensional Tikhonov-Fenichel parameters and their…

Dynamical Systems · Mathematics 2023-03-21 Justin Eilertsen , Santiago Schnell

The complexity of mathematical models in biology has rendered model reduction an essential tool in the quantitative biologist's toolkit. For stochastic reaction networks described using the Chemical Master Equation, commonly used methods…

Quantitative Methods · Quantitative Biology 2023-03-29 K. Öcal , G. Sanguinetti , R. Grima

In the past the study of reaction-diffusion systems has greatly contributed to our understanding of the behavior of many-body systems far from equilibrium. In this paper we aim at characterizing the properties of diffusion limited reactions…

Statistical Mechanics · Physics 2015-05-14 Sven Dorosz , Michel Pleimling

The present paper is devoted to the investigation of the long term behavior of a class of singular multi-dimensional diffusion processes that get absorbed in finite time with probability one. Our focus is on the analysis of quasi-stationary…

Probability · Mathematics 2021-02-12 Alexandru Hening , Weiwei Qi , Zhongwei Shen , Yingfei Yi

In this work we study the diffusion mechanisms in lithium disilicate melt using molecular dynamics simulation, which has an edge over other simulation methods because it can track down actual atomic rearrangements in materials once a…

Materials Science · Physics 2014-05-30 Luis G. V. Gonçalves , José P. Rino

The stationary state of stochastic processes such as reaction-diffusion systems can be related to the ground state of a suitably defined quantum Hamiltonian. Using this analogy, we investigate the applicability of a real space…

Statistical Mechanics · Physics 2007-05-23 J. Hooyberghs , C. Vanderzande

Reaction-diffusion systems can describe a wide class of rhythmic spatiotemporal patterns observed in chemical and biological systems, such as circulating pulses on a ring, oscillating spots, target waves, and rotating spirals. These…

Pattern Formation and Solitons · Physics 2014-06-03 Hiroya Nakao , Tatsuo Yanagita , Yoji Kawamura

Systems composed of large numbers of interacting agents often admit an effective coarse-grained description in terms of a multidimensional stochastic dynamical system, driven by small-amplitude intrinsic noise. In applications to…

Probability · Mathematics 2017-03-30 Todd L. Parsons , Tim Rogers

It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' on a wide class of biologically relevant,…

Probability · Mathematics 2014-01-20 David F. Anderson , German Enciso , Matthew Johnston