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Related papers: Quasi-steady state reduction for the Michaelis-Men…

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This paper proposes a novel reaction-diffusion system approximation tailored for singular diffusion problems, typified by the fast diffusion equation. While such approximation methods have been successfully applied to degenerate parabolic…

Analysis of PDEs · Mathematics 2026-04-01 Hideki Murakawa , Florian Salin

A kinetic description of lattice-gas automaton models for reaction-diffusion systems is presented. It provides corrections to the mean-field rate equations in the diffusion-limited regime. When applied to the two-species Maginu model, the…

Chemical Physics · Physics 2009-10-30 H. J. Bussemaker , R. Brito

We study quasilinear reaction diffusion systems relative to the Shigesada-Kawasaki-Teramoto model. Nonlinearity standing for the external force is provided with mass dissipation. Estimate in several norms of the solution is provided under…

Analysis of PDEs · Mathematics 2021-03-05 Evangelos Latos , Takashi Suzuki

In this work we investigate the convergence to equilibrium for mass action reaction-diffusion systems which model irreversible enzyme reactions. Using the standard entropy method in this situation is not feasible as the irreversibility of…

Analysis of PDEs · Mathematics 2022-03-14 Marcel Braukhoff , Amit Einav , Bao Quoc Tang

Q-conditional symmetries (nonclassical symmetries) for a general class of two-component reaction-diffusion systems with constant diffusivities are studied. Using the recently introduced notion of Q-conditional symmetries of the first type…

Mathematical Physics · Physics 2019-09-17 Roman Cherniha , Vasyl' Davydovych

Diffusion within porous media, such as biological tissues, exhibits departures from conventional Fick's laws, which could result in space-fractional diffusion. The paper considers a reaction-diffusion system with two spatial compartments --…

General Mathematics · Mathematics 2025-11-12 Dimiter Prodanov

In the current paper the so-called REaction-DIffusion Manifold (REDIM) method of model reduction is discussed within the framework of standard singular perturbation theory. According to the REDIM a reduced model for the system describing a…

Numerical Analysis · Mathematics 2017-01-31 V. Bykov , Y. Cherkinsky , V. Gol'dshtein , N. Krapivnik , U. Maas

We study a Michaelis-Menten reaction for a single two-state enzyme molecule, whose transition rates between the two conformations are modulated by an harmonically oscillating external force. In particular, we obtain a range of optimal…

Biomolecules · Quantitative Biology 2007-05-23 Michael A. Lomholt , Michael Urbakh , Ralf Metzler , Joseph Klafter

We establish sufficient conditions for exponential convergence to a unique quasi-stationary distribution in the total variation norm. These conditions also ensure the existence and exponential ergodicity of the Q-process, the process…

Probability · Mathematics 2023-08-01 Aurélien Velleret

The celebrated Michaelis-Menten (MM) expression provides a fundamental relation between the rate of enzyme catalysis and substrate concentration. The validity of this classical expression is, however, restricted to macroscopic amounts of…

Biological Physics · Physics 2019-05-09 Arti Dua

The trend to equilibrium for reaction-diffusion systems modelling chemical reaction networks is investigated, in the case when reaction processes happen on subsets of the domain. We prove the convergence to equilibrium by directly showing…

Analysis of PDEs · Mathematics 2024-12-17 Laurent Desvillettes , Kim Dang Phung , Bao Quoc Tang

We study the effect of restart, and retry, on the mean completion time of a generic process. The need to do so arises in various branches of the sciences and we show that it can naturally be addressed by taking advantage of the classical…

Statistical Mechanics · Physics 2020-10-30 Tal Rotbart , Shlomi Reuveni , Michael Urbakh

We study a class of Stochastic Differential Equations (SDEs) with jumps modeling multistage Michaelis--Menten enzyme kinetics, in which a substrate is sequentially transformed into a product via a cascade of intermediate complexes. These…

Probability · Mathematics 2026-04-14 Arnab Ganguly , Wasiur R. KhudaBukhsh

The quasi-steady-state approximation (QSSA) is a standard technique for reducing the complexity of chemical reaction networks (CRNs). The validity of any QSSA-based model is restricted to specific parameter regimes. Selecting the…

Dynamical Systems · Mathematics 2026-01-21 Timothy Earl Figueroa Lapuz , Martin Wechselberger

The quasi-steady-state assumption (QSSA) is an approximation that is widely used in chemistry and chemical engineering to simplify reaction mechanisms. The key step in the method requires a solution by radicals of a system of multivariate…

Dynamical Systems · Mathematics 2025-05-16 Ophelia Adams

We consider the finite volume approximation of a reaction-diffusion system with fast reversible reaction. We deduce from a priori estimates that the approximate solution converges to the weak solution of the reaction-diffusion problem and…

Analysis of PDEs · Mathematics 2008-08-05 R. Eymard , D. Hilhorst , M. Olech

A different view of Henri-Michaelis-Menten (HMM) enzyme kinetics is presented. In the first part of the paper, a simplified but useful description that stresses the cyclic nature of the catalytic process is introduced. The time-dependence…

Chemical Physics · Physics 2009-05-07 Mario N. Berberan-Santos

Computational feasibility of turbulent reacting flows hinges on the reduction of large chemical kinetics systems to smaller more manageable reaction sets. Recently, several sophisticated reduction techniques have been developed but they…

Chemical Physics · Physics 2012-02-17 Sharath Girimaji , Ashraf Ibrahim

The convergence to equilibrium of mass action reaction-diffusion systems arising from networks of chemical reactions is studied. The considered reaction networks are assumed to satisfy the detailed balance condition and have no boundary…

Analysis of PDEs · Mathematics 2017-02-13 Klemens Fellner , Bao Quoc Tang

We show that, for any spatially discretized system of reaction-diffusion, the approximate solution given by the explicit Euler time-discretization scheme converges to the exact time-continuous solution, provided that diffusion coefficient…

Optimization and Control · Mathematics 2019-12-12 Adrien Le Coënt , Laurent Fribourg