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Recent investigations have provided important insights into the complex structure and dynamics of collectively moving flocks of living organisms. Two intriguing observations are, scale-free correlations in the velocity fluctuations, in the…

Biological Physics · Physics 2022-03-22 Kunal Bhattacharya , Abhijit Chakraborty

Growing monolayers of rod-shaped bacteria exhibit local alignment similar to extensile active nematics. When confined in a channel or growing inward from a ring, the local nematic order of these monolayers changes to a global ordering with…

Soft Condensed Matter · Physics 2024-11-04 Blake Langeslay , Gabriel Juarez

Single-cell experiments revealed substantial variability in generation times, growth rates but also in birth and division sizes between genetically identical cells. Understanding how these fluctuations determine the fitness of the…

Populations and Evolution · Quantitative Biology 2025-03-24 Arthur Genthon

Cell extravasation is a crucial step of the metastatic cascade. In this process, the circulating tumor cells inside the blood vessels adhere to the cell monolayer of the blood vessel wall and passes through it, which allows them to invade…

Tissues and Organs · Quantitative Biology 2019-12-02 A. Nieto , J. Escribano , F. Spill , J. M. Garcia-Aznar , M. J. Gomez-Benito

We formulate a hydrodynamic theory of confluent epithelia: i.e. monolayers of epithelial cells adhering to each other without gaps. Taking advantage of recent progresses toward establishing a general hydrodynamic theory of p-atic liquid…

Soft Condensed Matter · Physics 2024-01-11 Josep-Maria Armengol-Collado , Livio Nicola Carenza , Luca Giomi

Collective cell migration is crucial in many biological processes such as wound healing, tissue morphogenesis, and tumor progression. The leading front of a collective migrating epithelial cell layer often destabilizes into multicellular…

Biological Physics · Physics 2020-05-07 Yanjun Yang , Herbert Levine

The motion of cells in tissues is an ubiquitous phenomenon. In particular, in monolayered cell colonies in vitro, pronounced collective behavior with swirl-like motion has been observed deep within a cell colony, while at the same time, the…

Biological Physics · Physics 2024-06-03 Debarati Sarkar , Gerhard Gompper , Jens Elgeti

Microbial growth and division are fundamental processes relevant to many areas of life science. Of particular interest are homeostasis mechanisms, which buffer growth and division from accumulating fluctuations over multiple cycles. These…

Cell Behavior · Quantitative Biology 2022-10-12 Lee Susman , Maryam Kohram , Harsh Vashistha , Jeffrey T. Nechleba , Hanna Salman , Naama Brenner

Erythropoiesis is a mechanism for the production of red blood cells by cellular differentiation. It is based on amplification steps due to an interplay between renewal and differentiation in the successive cell compartments from stem cells…

Probability · Mathematics 2019-12-12 Celine Bonnet , Sylvie Méléard

The effect of a randomly fluctuating gap, created by a random staggered potential, is studied in a monolayer and a bilayer of graphene. The density of states, the one-particle scattering rate and transport properties (diffusion coefficient…

Mesoscale and Nanoscale Physics · Physics 2009-03-24 K. Ziegler

We investigate sample-to-sample fluctuations of the shear modulus in ensembles of particle packings near the jamming transition. Unlike the average modulus, which exhibits distinct scaling behaviours depending on the interparticle…

Soft Condensed Matter · Physics 2026-03-06 Kumpei Shiraishi , Hideyuki Mizuno

We study experimentally the motion of an intruder dragged into an amorphous monolayer of horizontally vibrated grains at high packing fractions. This motion exhibits two transitions. The first transition separates a continuous motion regime…

Soft Condensed Matter · Physics 2010-03-02 Raphael Candelier , Olivier Dauchot

It is increasingly being realized that liquid-crystalline features can play an important role in the properties and dynamics of cell monolayers. Here, we present a cell-based model of cell layers, based on the phase-field formulation, that…

Soft Condensed Matter · Physics 2022-04-28 Aleksandra Ardaševa , Romain Mueller , Amin Doostmohammadi

Transitions between solid-like and fluid-like states in living tissues have been found in steps of embryonic development and in stages of disease progression. Our current understanding of these transitions has been guided by experimental…

Soft Condensed Matter · Physics 2024-11-20 Steven J. Chisolm , Emily Guo , Vignesh Subramaniam , Kyle D. Schulze , Thomas E. Angelini

Recent studies on epistatic networks of model organisms have unveiled a certain type of modular property called monochromaticity in which the networks are clusterable into functional modules that interact with each other through the same…

Molecular Networks · Quantitative Biology 2013-05-30 Arda Halu , Ginestra Bianconi

We studied regenerating bilayered tissue toroids dissected from Hydra vulgaris polyps and relate our macroscopic observations to the dynamics of force-generating mesoscopic cytoskeletal structures. Tissue fragments undergo a specific…

We perform cell segmentation on images from experimental studies of confluent, mobile cells in epithelial monolayers and show that these systems possess a broad, positively-skewed shape parameter distribution $P(\mathcal{A})$, where…

Recent experiments suggest that the interplay between cells and the mechanics of their substrate gives rise to a diversity of morphological and migrational behaviors. Here, we develop a Cellular Potts Model of polarizing cells on a…

Orientational and positional ordering properties of liquid crystal monolayers are examined by means of Fundamental-Measure Density Functional Theory. Particles forming the monolayer are modeled as hard parallelepipeds of square section of…

Soft Condensed Matter · Physics 2015-06-19 Yuri Martinez-Raton , Szabolcs Varga y Enrique Velasco

The dynamical properties of a dense horizontally vibrated bidisperse granular monolayer are experimentally investigated. The quench protocol produces states with a frozen structure of the assembly, but the remaining degrees of freedom…

Soft Condensed Matter · Physics 2008-08-26 F. Lechenault , O. Dauchot , G. Biroli , J. -P. Bouchaud
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